Zobrazeno 1 - 10
of 555
pro vyhledávání: '"Olaf Dössel"'
Autor:
Karli Gillette, Matthias A. F. Gsell, Claudia Nagel, Jule Bender, Benjamin Winkler, Steven E. Williams, Markus Bär, Tobias Schäffter, Olaf Dössel, Gernot Plank, Axel Loewe
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-19 (2023)
Abstract Mechanistic cardiac electrophysiology models allow for personalized simulations of the electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface. As such, synthetic signals possess known ground truth labels
Externí odkaz:
https://doaj.org/article/133e58ea690742a3824f8cfeb59d6608
Autor:
Nils Strodthoff, Temesgen Mehari, Claudia Nagel, Philip J. Aston, Ashish Sundar, Claus Graff, Jørgen K. Kanters, Wilhelm Haverkamp, Olaf Dössel, Axel Loewe, Markus Bär, Tobias Schaeffter
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-11 (2023)
Abstract Machine learning (ML) methods for the analysis of electrocardiography (ECG) data are gaining importance, substantially supported by the release of large public datasets. However, these current datasets miss important derived descriptors such
Externí odkaz:
https://doaj.org/article/8b93f501656f4e74b44fe9157c3554ac
Autor:
Benjamin Winkler, Claudia Nagel, Nando Farchmin, Sebastian Heidenreich, Axel Loewe, Olaf Dössel, Markus Bär
Publikováno v:
Metrology, Vol 3, Iss 1, Pp 1-28 (2022)
The numerical modeling of cardiac electrophysiology has reached a mature and advanced state that allows for quantitative modeling of many clinically relevant processes. As a result, complex computational tasks such as the creation of a variety of ele
Externí odkaz:
https://doaj.org/article/cbd345405a9a47878a91bfa240e81569
Publikováno v:
BioMedical Engineering OnLine, Vol 20, Iss 1, Pp 1-28 (2021)
Abstract Background Hypertrophic cardiomyopathy (HCM) is typically caused by mutations in sarcomeric genes leading to cardiomyocyte disarray, replacement fibrosis, impaired contractility, and elevated filling pressures. These varying tissue propertie
Externí odkaz:
https://doaj.org/article/ec4b253f44434f0a91ca08648e9be80c
Publikováno v:
Hearts, Vol 2, Iss 3, Pp 350-368 (2021)
Computer modeling of the electrophysiology of the heart has undergone significant progress. A healthy heart can be modeled starting from the ion channels via the spread of a depolarization wave on a realistic geometry of the human heart up to the pot
Externí odkaz:
https://doaj.org/article/aeca9846961c428c8ef5c621ff272ccb
Autor:
Jimena G. Siles-Paredes, Christopher J. Crowley, Flavio H. Fenton, Neal Bhatia, Shahriar Iravanian, Italo Sandoval, Stefan Pollnow, Olaf Dössel, João Salinet, Ilija Uzelac
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Conduction velocity (CV) slowing is associated with atrial fibrillation (AF) and reentrant ventricular tachycardia (VT). Clinical electroanatomical mapping systems used to localize AF or VT sources as ablation targets remain limited by the number of
Externí odkaz:
https://doaj.org/article/871fe0bfa7c541f994a49df42b21a4eb
Autor:
Giorgio Luongo, MSc, Luca Azzolin, MSc, Steffen Schuler, MSc, Massimo W. Rivolta, PhD, Tiago P. Almeida, PhD, Juan P. Martínez, PhD, Diogo C. Soriano, PhD, Armin Luik, MD, Björn Müller-Edenborn, MD, Amir Jadidi, MD, Olaf Dössel, PhD, Roberto Sassi, PhD, Pablo Laguna, PhD, Axel Loewe, PhD
Publikováno v:
Cardiovascular Digital Health Journal, Vol 2, Iss 2, Pp 126-136 (2021)
Background: Atrial fibrillation (AF) is the most common supraventricular arrhythmia, characterized by disorganized atrial electrical activity, maintained by localized arrhythmogenic atrial drivers. Pulmonary vein isolation (PVI) allows to exclude PV-
Externí odkaz:
https://doaj.org/article/946de344e92d48cfb0257024a32dae0f
Autor:
Yannick Lutz, Rosa Daschner, Lorena Krames, Axel Loewe, Giorgio Cattaneo, Stephan Meckel, Olaf Dössel
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 2, Pp 1147-1167 (2020)
Therapeutic hypothermia (TH) is an approved neuroproctetive treatment to reduce neurological morbidity and mortality after hypoxic-ischemic damage related to cardiac arrest and neonatal asphyxia. Also in the treatment of acute ischemic stroke (AIS),
Externí odkaz:
https://doaj.org/article/5da8ada7e9b3443f9b895f9802f65500
Autor:
Giorgio Luongo, Felix Rees, Deborah Nairn, Massimo W. Rivolta, Olaf Dössel, Roberto Sassi, Christoph Ahlgrim, Louisa Mayer, Franz-Josef Neumann, Thomas Arentz, Amir Jadidi, Axel Loewe, Björn Müller-Edenborn
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
AimsAtrial fibrillation (AF) and heart failure often co-exist. Early identification of AF patients at risk for AF-induced heart failure (AF-HF) is desirable to reduce both morbidity and mortality as well as health care costs. We aimed to leverage the
Externí odkaz:
https://doaj.org/article/4f59f2f7c1b74675b829a864dcae0902
Autor:
Jochen Brenneisen, Anna Daub, Tobias Gerach, Ekaterina Kovacheva, Larissa Huetter, Bettina Frohnapfel, Olaf Dössel, Axel Loewe
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: The human heart is a masterpiece of the highest complexity coordinating multi-physics aspects on a multi-scale range. Thus, modeling the cardiac function in silico to reproduce physiological characteristics and diseases remains challengin
Externí odkaz:
https://doaj.org/article/a1a001ca5e944b2f91c8b5ae01683ed0