Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Olaf Kutsch"'
Autor:
Leila B. Giron, Qin Liu, Opeyemi S. Adeniji, Xiangfan Yin, Toshitha Kannan, Jianyi Ding, David Y. Lu, Susan Langan, Jinbing Zhang, Joao L. L. C. Azevedo, Shuk Hang Li, Sergei Shalygin, Parastoo Azadi, David B. Hanna, Igho Ofotokun, Jason Lazar, Margaret A. Fischl, Sabina Haberlen, Bernard Macatangay, Adaora A. Adimora, Beth D. Jamieson, Charles Rinaldo, Daniel Merenstein, Nadia R. Roan, Olaf Kutsch, Stephen Gange, Steven M. Wolinsky, Mallory D. Witt, Wendy S. Post, Andrew Kossenkov, Alan L. Landay, Ian Frank, Phyllis C. Tien, Robert Gross, Todd T. Brown, Mohamed Abdel-Mohsen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract People living with HIV (PLWH) experience increased vulnerability to premature aging and inflammation-associated comorbidities, even when HIV replication is suppressed by antiretroviral therapy (ART). However, the factors associated with this
Externí odkaz:
https://doaj.org/article/834ccc7d78f64593bd700f4fd920f417
Autor:
Sanghita Sarkar, Dave D. Hill, Alexander F. Rosenberg, Ellen F. Eaton, Olaf Kutsch, James J. Kobie
Publikováno v:
Cells, Vol 13, Iss 12, p 1011 (2024)
The opioid epidemic continues to be a major public health issue that includes millions of people who inject drugs (PWID). PWID have increased incidence of serious infections, including HIV as well as metabolic and inflammatory sequelae. We sought to
Externí odkaz:
https://doaj.org/article/5041e70a560640e49b4487438476f987
Autor:
Fangming Zhu, Ryan J. McMonigle, Andrew R. Schroeder, Xianyou Xia, David Figge, Braxton D. Greer, Edahí González-Avalos, Diego O. Sialer, Yin-Hu Wang, Kelly M. Chandler, Adam J. Getzler, Emily R. Brown, Changchun Xiao, Olaf Kutsch, Yohsuke Harada, Matthew E. Pipkin, Hui Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Follicular helper T (Tfh) cells are essential for germinal center (GC) B cell responses. However, it is not clear which PD-1+CXCR5+Bcl6+CD4+ T cells will differentiate into PD-1hiCXCR5hiBcl6hi GC-Tfh cells and how GC-Tfh cell differentiation
Externí odkaz:
https://doaj.org/article/35c086446d634d7882db802bef9f3af3
Autor:
Anjana Delpe-Acharige, Man Zhang, Kayla Eschliman, Alex Dalecki, Obdulia Covarrubias-Zambrano, Azriel Minjarez-Almeida, Tejaswi Shrestha, Tanji Lewis, Fatimah Al-Ibrahim, Sophia Leonard, Riana Roberts, Anteneh Tebeje, Aruni P. Malalasekera, Hongwang Wang, Madumali Kalubowilage, Frank Wolschendorf, Olaf Kutsch, Stefan H. Bossmann
Publikováno v:
ACS Omega, Vol 6, Iss 9, Pp 6088-6099 (2021)
Externí odkaz:
https://doaj.org/article/a49e40a501dc45e99f257d2a54e6684f
Autor:
Eric Carlin, Braxton Greer, Kelsey Lowman, Alexandra Duverger, Frederic Wagner, David Moylan, Alexander Dalecki, Shekwonya Samuel, Mildred Perez, Steffanie Sabbaj, Olaf Kutsch
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1008748 (2021)
The biomolecular mechanisms controlling latent HIV-1 infection, despite their importance for the development of a cure for HIV-1 infection, are only partially understood. For example, ex vivo studies have recently shown that T cell activation only tr
Externí odkaz:
https://doaj.org/article/ad4ecc2c0cd44cc490fae2f38c691585
Autor:
Qing Wei, Audra A. Hargett, Barbora Knoppova, Alexandra Duverger, Reda Rawi, Chen-Hsiang Shen, S. Katie Farney, Stacy Hall, Rhubell Brown, Brandon F. Keele, Sonya L. Heath, Michael S. Saag, Olaf Kutsch, Gwo-Yu Chuang, Peter D. Kwong, Zina Moldoveanu, Milan Raska, Matthew B. Renfrow, Jan Novak
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101711- (2020)
Summary: HIV-1 envelope (Env) N-glycosylation impact virus-cell entry and immune evasion. How each glycan interacts to shape the Env-protein-sugar complex and affects Env function is not well understood. Here, analysis of two Env variants from the sa
Externí odkaz:
https://doaj.org/article/97d68eded382416db35fa1ea7937889b
Autor:
Mark E. Pepin, Lindsey E. Padgett, Ruth E. McDowell, Ashley R. Burg, Manoja K. Brahma, Cassie Holleman, Teayoun Kim, David Crossman, Olaf Kutsch, Hubert M. Tse, Adam R. Wende, Kirk M. Habegger
Publikováno v:
Molecular Metabolism, Vol 12, Iss , Pp 48-61 (2018)
Objective: Breakthroughs in HIV treatment, especially combination antiretroviral therapy (ART), have massively reduced AIDS-associated mortality. However, ART administration amplifies the risk of non-AIDS defining illnesses including obesity, diabete
Externí odkaz:
https://doaj.org/article/fedf00fc7bf543b3ab7496c3a6c6834c
Autor:
Katherine G. Michel, Jee-Young Moon, Olaf Kutsch, Michael Augenbraun, David B. Hanna, Alan L. Landay, Nadia R. Roan, Adaora A. Adimora, Robert C. Kaplan, Seema Desai, Brandilyn A. Peters, Anjali Sharma, Stephen J. Gange, Margaret A. Fischl, Caitlin A. Moran
Publikováno v:
J Infect Dis
Summary In women with HIV, higher activation and exhaustion of CD4+ T cells were associated with risk of non-HIV-related mortality during a median of 13.3 years of follow-up, independent of baseline demographic, behavioral, HIV-related, and cardiomet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e85bc88aa568483d479970f6fe5a01f
https://doi.org/10.1093/infdis/jiab433
https://doi.org/10.1093/infdis/jiab433
Autor:
Alex G. Dalecki, Obdulia Covarrubias-Zambrano, Riana Roberts, Frank Wolschendorf, Tanji Lewis, Tejaswi Shrestha, Fatimah Al-Ibrahim, Stefan H. Bossmann, Hongwang Wang, Sophia Leonard, Aruni P. Malalasekera, Olaf Kutsch, Madumali Kalubowilage, Kayla Eschliman, Azriel Minjarez-Almeida, Man Zhang, Anteneh Tebeje, Anjana Delpe-Acharige
Publikováno v:
ACS Omega, Vol 6, Iss 9, Pp 6088-6099 (2021)
ACS Omega
ACS Omega
A novel series of copper-activatable drugs intended for use against methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) were synthesized, characterized, and tested against the MSSA strain Newman and the MRSA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::472cc28c77ebb0479781ac5b437c5349
https://doaj.org/article/a49e40a501dc45e99f257d2a54e6684f
https://doaj.org/article/a49e40a501dc45e99f257d2a54e6684f
Autor:
Eric Carlin, Braxton Greer, Kelsey Lowman, Alexander G. Dalecki, Alexandra Duverger, Frederic Wagner, Olaf Kutsch
Publikováno v:
J Virol
Despite the clinical importance of latent human immunodeficiency virus type 1 (HIV-1) infection, our understanding of the biomolecular processes involved in HIV-1 latency control is still limited. This study was designed to address whether interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ded42260ef7fa51d8efd0c7cbf9f657f
https://pubmed.ncbi.nlm.nih.gov/35266804
https://pubmed.ncbi.nlm.nih.gov/35266804