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Publikováno v:
Bacterial Artificial Chromosomes
Strategies for altering sequences in large DNA inserts in BACs are fundamentally different from those traditionally used for small plasmids. Two factors are primarily responsible for this: the existence of a high multiplicity of sites in BACs recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df165361e41ffd5034dacdac60008f71
https://doi.org/10.5772/32443
https://doi.org/10.5772/32443
Autor:
Katya K. De La Torre, Derek C. Norford, Mugtaba A Eltayeb, Hope M. Wolf, Pradeep K. Chatterjee, Charles Hatcher, Leighcraft A. Shakes, Kevin O. Nyabera, Oladoyin Iranloye
Publikováno v:
Molecular Biology and Genetic Engineering. 2:2
Large pieces of DNA from the chromosomes of numerous organisms, including the human, are faithfully propagated in bacteria as large extra-chromosomal plasmids known as Bacterial Artificial Chromosomes (BACs). Because they