Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Ola A. Sharaf"'
1
Effect of (+) and (-) hydroxycitric acid sterio-isomers present in natural products in counteracting insulin resistance
Autor: Mohammed F. El-Yamany, Rania F. Ahmed, Hadir Farouk, Ola A. Sharaf, Ezz El-Din S. Eldenshary, Sawsan S. Mahmoud, Muhammed A. Saad
Publikováno v: Egyptian Journal of Chemistry.
Metabolic syndrome is a cluster of cardiovascular and metabolic risk factors that include impaired glucose metabolism and obesity. The use of nutraceuticals is an ideal choice for controlling this disorder. The aim of the present study is to investig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b8d9aad1f857d96b9278ddeb4a2e3fec
https://doi.org/10.21608/ejchem.2020.25054.2493
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2
Long term treatment of fluexotine and buspirone on gastric mucosal integrity in rats
Autor: Ola Abdelaziz Sharaf, Nawal S. Gomaa, Azza A. Ali, Enaiat Omara, Gehad A. Abdel-Jaleel
Publikováno v: African Journal of Pharmacy and Pharmacology. 10:737-747
The highly selective serotonin reuptake inhibitors are successful in the treatment of depression mood and anxiety disorders. The objective of this study is to investigate the effect of fluexotine and buspirone when given orally in three dose levels (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01d584a42e4b46aa738cb6a91a81ec9e
https://doi.org/10.5897/ajpp2016.4575
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3
Omega-3 fatty acids ameliorate doxorubicin-induced cardiorenal toxicity: In-vivo regulation of oxidative stress, apoptosis and renal Nox4, and in-vitro preservation of the cytotoxic efficacy
Autor: Rehab A. Hegazy, Ola A. Sharaf, Sawsan S. Mahmoud, Marawan Abdelbaset, Dalia O. Saleh, Azza Hassan
Publikováno v: PLoS ONE
PLoS ONE, Vol 15, Iss 11, p e0242175 (2020)
This study examines the protective effects of omega‐3 fatty acids (OMG), a frequently used nutritional therapy in cancer patients, against doxorubicin (DOX)‐induced acute cardiorenal toxicity in rats, and evaluates the cytotoxic activity of DOX w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1935eb888537c1946afc534a7afdd579
https://doi.org/10.1371/journal.pone.0242175
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4
Fingolimod interrupts the cross talk between estrogen metabolism and sphingolipid metabolism within prostate cancer cells
Autor: Ola A. Sharaf, Alaa Khedr, Salwa M. Nofal, Rasha M. Allam, Ashraf B. Abdel-Naim, Ahmed M. Al-Abd, Amani E. Khalifa, Hisham A. Mosli
Publikováno v: Toxicology letters. 291
Sphingolipids are critical regulators of tumor microenvironments and play an important role in estrogen-dependent cancers. Estrogen and estrogen metabolites were found to be involved in prostate cancer. Fingolimod (FTY720) is a sphingokinase-1 (SphK1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efbf9065a2a6dcd93217244c85ea0cb
https://pubmed.ncbi.nlm.nih.gov/29654831
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6
Abstract 2115: Therapeutic potential of fingolimod against prostate cancer cells is partly attributed to interrupting the cross talk between estrogen and sphingolipid metabolisms
Autor: Ola A. Sharaf, Ahmed M. Al-Abd, Alaa Khedr, Rasha M. Allam, Amani E. Khalifa, Salwa M. Nofal, Hisham A. Mosli, Ashraf B. Abdel-Naim
Publikováno v: Cancer Research. 77:2115-2115
Sphingolipids influence tumor microenvironment in different malignancies. Estrogen and estrogen metabolites are involved in prostate cancer. Fingolimod is Sphingokinase-1 (SphK1) inhibitor which possesses anticancer properties in various tumor types.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ad7348a0e4c4a9a38cf4df3632c5b34
https://doi.org/10.1158/1538-7445.am2017-2115
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7
Hepatoprotective effects of Astragalus kahiricus root extract against ethanol-induced liver apoptosis in rats
Autor: Asser I. Ghoneim, Mohamed M. Radwan, Ola A. Sharaf, Soad M. Toaima, Nadia A. El-Sebakhy, Rasha M. Allam, Amani E. Khalifa, Salwa M. Nofal, Dina A. Selim, Aya M. Asaad
Publikováno v: Chinese journal of natural medicines. 11(4)
The hepatoprotective activity of the ethanol extract of Astragalus kahiricus (Fabaceae) roots against ethanol-induced liver apoptosis was evaluated and it showed very promising hepatoprotective actions through different mechanisms. The extract counte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc37c8b6470321f5f8cb230cbdd61650
https://pubmed.ncbi.nlm.nih.gov/23845543
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