Exploring the Therapeutic Potential of Ampelopsis grossedentata Leaf Extract as an Anti-Inflammatory and Antioxidant Agent in Human Immune Cells

Autor: Arthur Chervet, Rawan Nehme, Caroline Decombat, Lucie Longechamp, Ola Habanjar, Amandine Rousset, Didier Fraisse, Christelle Blavignac, Edith Filaire, Jean-Yves Berthon, Laetitia Delort, Florence Caldefie-Chezet

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 1, p 416 (2023)

Inflammation is a vital protective response to threats, but it can turn harmful if chronic and uncontrolled. Key elements involve pro-inflammatory cells and signaling pathways, including the secretion of pro-inflammatory cytokines, NF-κB, reactive o

Externí odkaz: https://doaj.org/article/69bc561fb58a4d3da4e459bc9230799f

The Impact of Obesity, Adipose Tissue, and Tumor Microenvironment on Macrophage Polarization and Metastasis

Autor: Ola Habanjar, Mona Diab-Assaf, Florence Caldefie-Chezet, Laetitia Delort

Publikováno v: Biology, Vol 11, Iss 2, p 339 (2022)

Tumor metastasis is a major cause of death in cancer patients. It involves not only the intrinsic alterations within tumor cells, but also crosstalk between these cells and components of the tumor microenvironment (TME). Tumorigenesis is a complex an

Externí odkaz: https://doaj.org/article/3c546ef50ba04d5c991bf31161348e2f

A bicellular fluorescent ductal carcinoma in situ (DCIS)-like tumoroid to study the progression of carcinoma: practical approaches and optimization

Autor: Ola Habanjar, Anne-Catherine Maurin, Cyrielle Vituret, Caroline Vachias, Lucie Longechamp, Cécile Garnier, Caroline Decombat, Céline Bourgne, Mona Diab-Assaf, Florence Caldefie-Chezet, Laetitia Delort

Publikováno v: Biomaterials Science
Biomaterials Science, 2023, 11 (9), pp.3308-3320. ⟨10.1039/d2bm01470j⟩

International audience; Recently, many types of 3D culture systems have been developed to preserve the physicochemical environment and biological characteristics of the original tumors better than the conventional 2D monolayer culture system. There a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17a877979c7165e7bb200a1031df082
https://uca.hal.science/hal-04103734

3D Cell Culture Systems: Tumor Application, Advantages, and Disadvantages

Autor: Florence Caldefie-Chezet, Ola Habanjar, Laetitia Delort, Mona Diab-Assaf

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22 (22), pp.12200. ⟨10.3390/ijms222212200⟩
International Journal of Molecular Sciences, Vol 22, Iss 12200, p 12200 (2021)

International audience; The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long been used in cancer research. However, this system cannot be fully translated into clinical trials to ideally represent physiologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb3fa6af318226a3ea586d7926754e1
https://hal.science/hal-03534726

Identification de facteurs préventifs de la transition du CCIS (carcinome canalaire in situ) vers un CCI (carcinome canalaire invasif) chez les femmes en surpoids ou obèses

Autor: Ola, HABANJAR, VERMERIE, M., Decombat, Caroline, Auxenfans, Celine, Diab-Assaf, Mona, Caldefie-Chezet, Florence, Delort, Laetitia

Publikováno v: Journée jeunes chercheurs du réseau NACRE
Journée jeunes chercheurs du réseau NACRE, Sep 2021, Paris, France

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::87bce359ea26e489f8123968f5f1169d
https://hal.archives-ouvertes.fr/hal-03434874