Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Olímpia Maria Martins Santos"'
Autor:
Rudy Bonfilio, Marília Cristina Oliveira Souza, Jockastta Silva Leal, Olímpia Maria Martins Santos Viana, Antônio Carlos Doriguetto, Magali Benjamin de Araújo
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 4 (2018)
ABSTRACT Different solid forms of an active pharmaceutical ingredient can have distinct chemical and physical characteristics. In this work, we studied the solubility and dissolution properties of the described tibolone polymorphic forms (I and II).
Externí odkaz:
https://doaj.org/article/5de1f64e1eb942129fd859a7c49379ed
Autor:
Rudy Bonfilio, Olímpia Maria Martins Santos, Zuleica Raquel de Novaes, Audrei Nunes Fernandes Matinatti, Magali Benjamim de Araújo
Publikováno v:
Revista de Ciências Farmacêuticas Básica e Aplicada, Vol 34, Iss 4, Pp 527-535 (2013)
O setor magistral promove o acesso da população a medicamentos essenciais e fornece produtos individualizados. Entretanto, a qualidade dos medicamentos manipulados no Brasil é frequentemente questionada, apesar de existirem poucos dados cient
Externí odkaz:
https://doaj.org/article/109e77549e5e4ddbae9951f098eca160
Autor:
Patrícia Alves Franco Gehring, Olímpia Maria Martins Santos, Gislaine Ribeiro Pereira, Magali Benjamim de Araújo, Rudy Bonfilio
Publikováno v:
Química Nova, Vol 34, Iss 3, Pp 455-461 (2011)
This work describes the establishment of dissolution test conditions for 75 mg cinnarizine capsules using a multivariate approach. A 2³ full factorial design was carried out to achieve the best conditions and HCl 0.1 mol L-1 as dissolution medium, b
Externí odkaz:
https://doaj.org/article/295fc55dc1334d1c94a364c6e98b9344
Autor:
Renata Cunha de Resende, Olímpia Maria Martins Santos Viana, Jennifer Tavares Jacon Freitas, Rudy Bonfilio, André Luís Morais Ruela, Magali Benjamim de Araújo
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 52, Iss 4, Pp 613-621
ABSTRACT Spironolactone (SPR) is a steroidal drug administered as a potassium-sparing diuretic for high blood pressure treatment. The drug shows incomplete gastrointestinal absorption due to its poor aqueous solubility. The physicochemical properties
Externí odkaz:
https://doaj.org/article/bcaa941258374b0bbca8c0c06664c08f
Autor:
Olímpia Maria Martins Santos, Maria Esther Dias Reis, Jennifer Tavares Jacon, Mônica Esselin de Sousa Lino, Juliana Savioli Simões, Antonio Carlos Doriguetto
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences; Vol. 50 No. 1 (2014); 1-24
Brazilian Journal of Pharmaceutical Sciences; Vol. 50 Núm. 1 (2014); 1-24
Brazilian Journal of Pharmaceutical Sciences; v. 50 n. 1 (2014); 1-24
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Volume: 50, Issue: 1, Pages: 1-24, Published: MAR 2014
Brazilian Journal of Pharmaceutical Sciences; Vol. 50 Núm. 1 (2014); 1-24
Brazilian Journal of Pharmaceutical Sciences; v. 50 n. 1 (2014); 1-24
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Volume: 50, Issue: 1, Pages: 1-24, Published: MAR 2014
O polimorfismo em sólidos é um fenômeno frequente em fármacos e pode levar a problemas na qualidade dos medicamentos por alterar suas propriedades físico-químicas, em especial a solubilidade e, consequentemente, a biodisponibilidade. Nesse trab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce88e9467324743dd2a07d4991f2d07f
https://www.revistas.usp.br/bjps/article/view/80847
https://www.revistas.usp.br/bjps/article/view/80847
Autor:
Olimpia Maria Martins Santos, Jennifer Tavares Jacon Freitas, Edith Cristina Laignier Cazedey, Magali Benjamim de Araújo, Antonio Carlos Doriguetto
Publikováno v:
Molecules, Vol 21, Iss 3, p 328 (2016)
Orbifloxacin (ORBI) is a widely used antimicrobial drug of the fluoroquinolone class. In the official pharmaceutical compendia the existence of polymorphism in this active pharmaceutical ingredient (API) is reported. No crystal structure has been rep
Externí odkaz:
https://doaj.org/article/475eb3e0888e43b6bb41656de0e69724