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Potential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells.
Autor:
Manoharan, Ganesh Babu1 (AUTHOR), Okutachi, Sunday1 (AUTHOR), Abankwa, Daniel1 (AUTHOR) daniel.abankwa@uni.lu
Publikováno v:
PLoS ONE. 5/26/2022, Vol. 17 Issue 5, p1-18. 18p.
Autor:
Okutachi, Sunday Ojochegbe
Mutations in the KRAS gene are associated with approximately 15% of all human cancers. This makes it one of the most frequently mutated oncogenes known. Whilst recent breakthroughs in Ras drug discovery have led to the FDA approval of the first direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2658::d75c4bcd1f0f3c99619a0627c0240c5d
http://orbilu.uni.lu/handle/10993/47512
http://orbilu.uni.lu/handle/10993/47512
Akademický článek
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Autor:
Siddiqui, Farid A, Alam, Catharina, Ora, Mikko, Sabt, Ahmed, Manoharan, Ganesh Babu, Bindu, Lakshman, Okutachi, Sunday, Catillon, Marie, Taylor, Troy, Abdelhafez, Omaima M, Lönnberg, Harri, Stephen, Andrew G, Papageorgiou, Anastassios C, Virta, Pasi, Abankwa, Daniel
The trafficking chaperone PDE6D (also referred to as PDEδ) has been nominated as a surrogate target for K-Ras4B (hereafter K-Ras). Arl2-assisted unloading of K-Ras from PDE6D in the perinuclear area is significant for correct K-Ras localization and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::06ab01e5b4dd1be565d79e401930b95c
Autor:
Ejima, Okutachi Sunday
Publikováno v:
ICHPER -- SD Journal; Spring2005, Vol. 41 Issue 2, p60-63, 4p