Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Oksana, Dmytriyeva"'
Autor:
Mia Apuschkin, Hayley B. Burm, Jan H. Schmidt, Louise J. Skov, Rita C. Andersen, Carl-Fredrik Bowin, Jonatan F. Støier, Kathrine L. Jensen, Leonie P. Posselt, Oksana Dmytriyeva, Andreas T. Sørensen, Kristoffer L. Egerod, Birgitte Holst, Mattias Rickhag, Thue W. Schwartz, Ulrik Gether
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114509- (2024)
Summary: Midbrain dopaminergic neurons (DANs) are subject to extensive metabotropic regulation, but the repertoire of G protein-coupled receptors (GPCRs) present in these neurons has not been mapped. Here, we isolate DANs from Dat-eGFP mice to genera
Externí odkaz:
https://doaj.org/article/133a9c01bbf2442d97dd45f84df3014d
Autor:
Kathrine Lundø, Oksana Dmytriyeva, Louise Spøhr, Eliana Goncalves-Alves, Jiayi Yao, Laia P. Blasco, Mette Trauelsen, Muthulakshmi Ponniah, Marc Severin, Albin Sandelin, Marie Kveiborg, Thue W. Schwartz, Stine F. Pedersen
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background The lactate receptor GPR81 contributes to cancer development through unclear mechanisms. Here, we investigate the roles of GPR81 in three-dimensional (3D) and in vivo growth of breast cancer cells and study the molecular mechanism
Externí odkaz:
https://doaj.org/article/4dce1bc40e524fe2bbe93834d25ecd0f
Autor:
Jacob Emil Petersen, Maria Hauge Pedersen, Oksana Dmytriyeva, Emilie Nellemose, Tulika Arora, Maja Storm Engelstoft, Wesley B. Asher, Jonathan A. Javitch, Thue W. Schwartz, Mette Trauelsen
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101757- (2023)
Objective: Free fatty acid receptor 1 (FFAR1) is highly expressed in enteroendocrine cells of the small intestine and pancreatic beta cells, where FFAR1 agonists function as GLP-1 and insulin secretagogues, respectively. Most efficacious are so-calle
Externí odkaz:
https://doaj.org/article/a28f704e33e846e698b98299456a1403
Autor:
Eva Baerends, Katia Soud, Jonas Folke, Anna-Kathrine Pedersen, Simon Henmar, Lisa Konrad, Matthew D. Lycas, Yuki Mori, Bente Pakkenberg, David P. D. Woldbye, Oksana Dmytriyeva, Stanislava Pankratova
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-21 (2022)
Abstract Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disease characterized by the accumulation of aggregated amyloid beta (Aβ) and hyperphosphorylated tau along with a slow decline in cognitive functions. Unlike ad
Externí odkaz:
https://doaj.org/article/8b3657b99e53449abba7ffb4c1079b6d
Autor:
Randi Bonke Mikkelsen, Tulika Arora, Kajetan Trošt, Oksana Dmytriyeva, Sune Kjærsgaard Jensen, Abraham Stijn Meijnikman, Louise Elisabeth Olofsson, Dimitra Lappa, Ömrüm Aydin, Jens Nielsen, Victor Gerdes, Thomas Moritz, Arnold van de Laar, Maurits de Brauw, Max Nieuwdorp, Siv Annegrethe Hjorth, Thue Walter Schwartz, Fredrik Bäckhed
Publikováno v:
iScience, Vol 25, Iss 12, Pp 105683- (2022)
Summary: Obesity and diabetes are associated with inflammation and altered plasma levels of several metabolites, which may be involved in disease progression. Some metabolites can activate G protein-coupled receptors (GPCRs) expressed on immune cells
Externí odkaz:
https://doaj.org/article/d9959421ddb94ab2875da795adbdc0af
Autor:
Jens Lund, Alberte Wollesen Breum, Cláudia Gil, Sarah Falk, Frederike Sass, Marie Sophie Isidor, Oksana Dmytriyeva, Pablo Ranea-Robles, Cecilie Vad Mathiesen, Astrid Linde Basse, Olivia Sveidahl Johansen, Nicole Fadahunsi, Camilla Lund, Trine Sand Nicolaisen, Anders Bue Klein, Tao Ma, Brice Emanuelli, Maximilian Kleinert, Charlotte Mehlin Sørensen, Zachary Gerhart-Hines, Christoffer Clemmensen
Publikováno v:
Nature Metabolism. 5:677-698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cb72d589cbf882c5c4ec5258969546c
https://doi.org/10.1038/s42255-023-00780-4
https://doi.org/10.1038/s42255-023-00780-4
Autor:
Ahmed M. Abdelmoez, Oksana Dmytriyeva, Yasemin-Xiomara Zurke, Mette Trauelsen, Alesandra A. Marica, Mladen Savikj, Jonathon A. B. Smith, Claudia Monaco, Thue W. Schwartz, Anna Krook, Nicolas J. Pillon
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 324:E289-E298
Macrophages but not skeletal muscle cells respond to extracellular succinate via SUCNR1/GPR91.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1041f588232278e92a8e087b55bd29c
https://doi.org/10.1152/ajpendo.00009.2023
https://doi.org/10.1152/ajpendo.00009.2023
Autor:
Karen Nørgaard Nielsen, Julia Peics, Tao Ma, Iuliia Karavaeva, Morten Dall, Sabina Chubanava, Astrid L. Basse, Oksana Dmytriyeva, Jonas T. Treebak, Zachary Gerhart-Hines
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 178-188 (2018)
Objective: The ability of adipose tissue to expand and contract in response to fluctuations in nutrient availability is essential for the maintenance of whole-body metabolic homeostasis. Given the nutrient scarcity that mammals faced for millions of
Externí odkaz:
https://doaj.org/article/fedae59f6f7b4c6a8086f0c57ba2e0f1
Autor:
Mari L. Lund, Kristoffer L. Egerod, Maja S. Engelstoft, Oksana Dmytriyeva, Elvar Theodorsson, Bhavik A. Patel, Thue W. Schwartz
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 70-83 (2018)
Objectives: 5-HT storing enterochromaffin (EC) cells are believed to respond to nutrient and gut microbial components, and 5-HT receptor-expressing afferent vagal neurons have been described to be the major sensors of nutrients in the GI-tract. Howev
Externí odkaz:
https://doaj.org/article/973b0545f5a14535b363aa036d4ce68f
Autor:
Dominika Czaplinska, Renata Ialchina, Henriette Berg Andersen, Jiayi Yao, Arnaud Stigliani, Johs Dannesboe, Mette Flinck, Xiaoming Chen, Jakub Mitrega, Sebastian Peter Gnosa, Oksana Dmytriyeva, Frauke Alves, Joanna Napp, Albin Sandelin, Stine Falsig Pedersen
Publikováno v:
International Journal of Cancer
Czaplinska, D, Ialchina, R, Andersen, H B, Yao, J, Stigliani, A, Dannesboe, J, Flinck, M, Chen, X, Mitrega, J, Gnosa, S P, Dmytriyeva, O, Alves, F, Napp, J, Sandelin, A & Pedersen, S F 2023, ' Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness ', International Journal of Cancer, vol. 152, no. 6, pp. 1210-1225 . https://doi.org/10.1002/ijc.34367
Czaplinska, D, Ialchina, R, Andersen, H B, Yao, J, Stigliani, A, Dannesboe, J, Flinck, M, Chen, X, Mitrega, J, Gnosa, S P, Dmytriyeva, O, Alves, F, Napp, J, Sandelin, A & Pedersen, S F 2023, ' Crosstalk between tumor acidosis, p53 and extracellular matrix regulates pancreatic cancer aggressiveness ', International Journal of Cancer, vol. 152, no. 6, pp. 1210-1225 . https://doi.org/10.1002/ijc.34367
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive malignancy with minimal treatment options and a global rise in prevalence. PDAC is characterized by frequent driver mutations including KRAS and TP53 (p53), and a dense, acidic tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c1f1b4aea4a4a89a3745f8fff18c02
https://hdl.handle.net/21.11116/0000-000C-45F6-121.11116/0000-000C-45F8-F
https://hdl.handle.net/21.11116/0000-000C-45F6-121.11116/0000-000C-45F8-F
