Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Okhyun Lee"'
Autor:
Aya Takesono, Paula Schirrmacher, Aaron Scott, Jon M. Green, Okhyun Lee, Matthew J. Winter, Tetsuhiro Kudoh, Charles R. Tyler
Publikováno v:
Development. 149
Estrogens are well-known to regulate development of sexual dimorphism of the brain; however, their role in embryonic brain development prior to sex-differentiation is unclear. Using estrogen biosensor zebrafish models, we found that estrogen activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd780f066d9940c76690cf17630f40d3
https://doi.org/10.1242/dev.199860
https://doi.org/10.1242/dev.199860
Autor:
Jon M. Green, Scott A, Schirrmacher P, Matthew J. Winter, Tetsuhiro Kudoh, Aya Takesono, Charles R. Tyler, Okhyun Lee
SummaryEstrogen is well-known to regulate development of sexual dimorphisms of the brain, however its role in the brain during early embryonic development prior to sex-differentiation is unclear.Using estrogen biosensor zebrafish models, we found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ccd63631ec831a38cff6f4e3c41ac2
https://doi.org/10.1101/2021.06.03.446864
https://doi.org/10.1101/2021.06.03.446864
Autor:
Tetsuhiro Kudoh, Jeremy Metz, Aya Takesono, Maciej Trznadel, Jon M. Green, Stewart F. Owen, A. Ross Brown, Okhyun Lee, Charles R. Tyler
Publikováno v:
Environmental Science & Technology. 50:6536-6545
Rapid embryogenesis, together with genetic similarities with mammals, and the desire to reduce mammalian testing, are major incentives for using the zebrafish model in chemical screening and testing. Transgenic zebrafish, engineered for identifying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f34b7bb0cc7a8eb9663146cd7496ac07
https://doi.org/10.1021/acs.est.6b01243
https://doi.org/10.1021/acs.est.6b01243
Publikováno v:
Environmental Science and Technology
Environmental Science and Technology, American Chemical Society, 2017, 51 (21), pp.12796-12805. ⟨10.1021/acs.est.7b03283⟩
Environmental Science and Technology, 2017, 51 (21), pp.12796-12805. ⟨10.1021/acs.est.7b03283⟩
Environmental Science and Technology, American Chemical Society, 2017, 51 (21), pp.12796-12805. ⟨10.1021/acs.est.7b03283⟩
Environmental Science and Technology, 2017, 51 (21), pp.12796-12805. ⟨10.1021/acs.est.7b03283⟩
International audience; Bisphenol A (BPA), a chemical incorporated into plastics and resins, has estrogenic activity and is associated with adverse health effects in humans and wildlife. Similarly structured BPA analogues are widely used but far less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c0a2f3a40637eb141ccaa13593325f
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01737330
https://hal-univ-rennes1.archives-ouvertes.fr/hal-01737330
Publikováno v:
Critical reviews in toxicology. 45(2)
The use of transgenics in fish is a relatively recent development for advancing understanding of genetic mechanisms and developmental processes, improving aquaculture, and for pharmaceutical discovery. Transgenic fish have also been applied in ecotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ce99b77cbf7842e1455ba2cbbe907a
https://pubmed.ncbi.nlm.nih.gov/25394772
https://pubmed.ncbi.nlm.nih.gov/25394772
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 12, Iss 1, p 32 (2012)
BMC Biotechnology, Vol 12, Iss 1, p 32 (2012)
Background Oestrogenic contaminants are widespread in the aquatic environment and have been shown to induce adverse effects in both wildlife (most notably in fish) and humans, raising international concern. Available detecting and testing systems are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbb15308a632beebff35aad0b9132f4
https://doi.org/10.1186/1472-6750-12-32
https://doi.org/10.1186/1472-6750-12-32
Publikováno v:
Environmental Health Perspectives
Background: Environmental estrogens alter hormone signaling in the body that can induce reproductive abnormalities in both humans and wildlife. Available testing systems for estrogens are focused on specific systems such as reproduction. Crucially, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab65ba8e27f94799b13d3d9d42e72dc3
https://pubmed.ncbi.nlm.nih.gov/22759863
https://pubmed.ncbi.nlm.nih.gov/22759863
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 163:S48-S49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef1a693b1ff41c08ee3403b050e904d9
https://doi.org/10.1016/j.cbpa.2012.05.142
https://doi.org/10.1016/j.cbpa.2012.05.142
Autor:
Green, Jon M.1, Metz, Jeremy1, Okhyun Lee1, Trznadel, Maciej1, Aya Takesono1, Brown, A. Ross1, Owen, Stewart F.2, Tetsuhiro Kudoh1, Tyler, Charles R.1 C.R.Tyler@exeter.ac.uk
Publikováno v:
Environmental Science & Technology. 6/21/2016, Vol. 50 Issue 12, p6536-6545. 10p.
Autor:
Taisen Iguchi, Aya Takesono, Gregory C. Paull, Amy L. Filby, Okhyun Lee, Tetsuhiro Kudoh, Patrick B. Hamilton, Charles R. Tyler, Anke Lange, M. Soffkar
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 163:S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c108d745f69b5947188a71c989b466
https://doi.org/10.1016/j.cbpa.2012.05.013
https://doi.org/10.1016/j.cbpa.2012.05.013