Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Okesli A"'
Autor:
Archana Vijayakumar, Ayse Okesli‐Armlovich, Ting Wang, Isabel Olson, Minji Seung, Saritha Kusam, David Hollenback, Sangeetha Mahadevan, Bruno Marchand, Maria Toteva, David G. Breckenridge, James L. Trevaskis, Jamie Bates
Publikováno v:
Hepatology Communications, Vol 6, Iss 9, Pp 2298-2309 (2022)
Abstract Dysregulated hepatocyte lipid metabolism is a hallmark of hepatic lipotoxicity and contributes to the pathogenesis of nonalcoholic steatohepatitis (NASH). Acetyl CoA carboxylase (ACC) inhibitors decrease hepatocyte lipotoxicity by inhibiting
Externí odkaz:
https://doaj.org/article/fcccdbbbcc8c483fa465bc4bd08eb25c
Autor:
Liu, Qi, Gupta, Amita, Okesli-Armlovich, Ayse, Qiao, Wenjie, Fischer, Curt R., Smith, Mark, Carette, Jan E., Bassik, Michael C., Khosla, Chaitan
Publikováno v:
In Cell Chemical Biology 18 June 2020 27(6):668-677
Autor:
Anastasia Hyrina, Dara Burdette, Zhijuan Song, Ricardo Ramirez, Ayse Okesli-Armlovich, Archana Vijayakumar, Jamie Bates, James L. Trevaskis, Simon P. Fletcher, William A. Lee, Meghan M. Holdorf
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
Chronic hepatitis B virus (HBV) infection is characterized by the presence of high circulating levels of non-infectious lipoprotein-like HBV surface antigen (HBsAg) particles thought to contribute to chronic immune dysfunction in patients. Lipid and
Externí odkaz:
https://doaj.org/article/5cb5456c3f804f678aceb51146756bf4
Is Intra-Articular Magnesium Effective for Postoperative Analgesia in Arthroscopic Shoulder Surgery?
Publikováno v:
Pain Research and Management, Vol 20, Iss 1, Pp 35-38 (2015)
BACKGROUND: Various medications are used intra-articularly for postoperative pain reduction after arthroscopic shoulder surgery. Magnesium, a N-methyl-D-aspartate receptor antagonist, may be effective for reduction of both postoperative pain scores a
Externí odkaz:
https://doaj.org/article/9c6fde703eb24ac7a265f1e495b8afc8
Akademický článek
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Akademický článek
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Publikováno v:
J Biol Chem
Macrolide antibiotics, such as erythromycin and josamycin, are natural polyketide products harboring 14- to 16-membered macrocyclic lactone rings to which various sugars are attached. These antibiotics are used extensively in the clinic because of th
Autor:
Marta Jimenez, Ayse Okesli-Armlovich, Chaitan Khosla, Douglas S. Auld, Michael C. Bassik, Amita Gupta, Qi Liu
Publikováno v:
Bioorg Med Chem Lett
Clinically relevant inhibitors of dihydroorotate dehydrogenase (DHODH), a rate-limiting enzyme in mammalian de novo pyrimidine synthesis, have strong antiviral and anticancer activity in vitro. However, they are ineffective in vivo due to efficient u
Autor:
Chung, Jinhwa A., Wollack, James W., Hovlid, Marisa L., Okesli, Ayse, Chen, Yan, Mueller, Joachim D., Distefano, Mark D., Taton, T. Andrew
Publikováno v:
In Analytical Biochemistry 2009 386(1):1-8
Autor:
Okesli-Armlovich, Ayse, Gupta, Amita, Jimenez, Marta, Auld, Douglas, Liu, Qi, Bassik, Michael C., Khosla, Chaitan
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 15 September 2019 29(18):2559-2564