Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology.

Autor: Mousa A; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Cuomo-Dannenburg G; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom., Thompson HA; Malaria and Neglected Tropical Diseases, PATH, Seattle, Washington, United States of America., Chico RM; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Beshir KB; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Sutherland CJ; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Schellenberg D; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Gosling R; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Malaria Elimination Initiative, Institute of Global Health, University of California, San Francisco, California, United States of America., Alifrangis M; Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark., Hocke EF; Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark., Hansson H; Center for Medical Parasitology, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.; Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark., Chopo-Pizarro A; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Mbacham WF; The Biotechnology Centre, University of Yaoundé, Yaoundé, Cameroon.; The Fobang Institutes for Innovation in Science and Technology, Yaoundé, Cameroon.; The Faculty of Northwest University, Faculty of Natural and Agricultural Sciences, Potchefstroom, South Africa., Ali IM; The Biotechnology Centre, University of Yaoundé, Yaoundé, Cameroon.; Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon., Chaponda M; Department of Clinical Sciences, Tropical Diseases Research Centre, Ndola, Zambia., Roper C; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Okell LC; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom.

Publikováno v: PLoS medicine [PLoS Med] 2024 May 09; Vol. 21 (5), pp. e1004376. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024).

Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context

Autor: Sheppard, R, Watson, OJ, Pieciak, R, Lungu, J, Kwenda, G, Moyo, C, Longa Chanda, S, Barnsley, G, Brazeau, NF, Gerard-Ursin, ICG, Olivera Mesa, D, Whittaker, C, Gregson, S, Okell, LC, Ghani, AC, MacLeod, WB, Del Fava, E, Melegaro, A, Hines, JZ, Mulenga, LB, Walker, P, Mwananyanda, L, Gill, CJ

Reported COVID-19 cases and associated mortality remain low in many sub-Saharan countries relative to global averages, but true impact is difficult to estimate given limitations around surveillance and mortality registration. In Lusaka, Zambia, buria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::a118a93f01a8fb9b9e3d15bcb88f027a
http://hdl.handle.net/10044/1/105005

Analysis of blood and nasal epithelial transcriptomes to identify mechanisms associated with control of SARS-CoV-2 viral load in the upper respiratory tract.

Autor: Moradi Marjaneh M; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK; Section of Virology, Department of Infectious Diseases, Imperial College London, London, UK. Electronic address: m.moradi@imperial.ac.uk., Challenger JD; Medical Research Council Centre for Global Infections Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK., Salas A; Unidade de Xenética, Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigación Sanitaria (IDIS), Hospital Clínico Universitario de Santiago (SERGAS), Galicia, Spain; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain., Gómez-Carballa A; Unidade de Xenética, Instituto de Ciencias Forenses, Facultade de Medicina, Universidade de Santiago de Compostela, and GenPoB Research Group, Instituto de Investigación Sanitaria (IDIS), Hospital Clínico Universitario de Santiago (SERGAS), Galicia, Spain; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain., Sivananthan A; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK., Rivero-Calle I; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain; Translational Pediatrics and Infectious Diseases, Department of Pediatrics, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Galicia, Spain., Barbeito-Castiñeiras G; Servicio de Microbiología y Parasitología, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Galicia, Spain., Foo CY; School of Medicine, Imperial College London, London, UK., Wu Y; Department of Surgery and Cancer, Imperial College London, St. Mary's Hospital, London, UK., Liew F; National Heart and Lung Institute, Imperial College London, London, UK., Jackson HR; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., Habgood-Coote D; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., D'Souza G; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., Nichols SJ; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., Wright VJ; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., Levin M; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., Kaforou M; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK., Thwaites RS; National Heart and Lung Institute, Imperial College London, London, UK., Okell LC; Medical Research Council Centre for Global Infections Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, UK., Martinón-Torres F; Genetics, Vaccines and Infections Research Group (GENVIP), Instituto de Investigación Sanitaria de Santiago, Universidade de Santiago de Compostela, Santiago de Compostela, Galicia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER-ES), Madrid, Spain; Translational Pediatrics and Infectious Diseases, Department of Pediatrics, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Galicia, Spain., Cunnington AJ; Section of Paediatric Infectious Disease, Department of Infectious Disease, Imperial College London, London, UK; Centre for Paediatrics and Child Health, Imperial College London, London, UK. Electronic address: a.cunnington@imperial.ac.uk.

Publikováno v: The Journal of infection [J Infect] 2023 Dec; Vol. 87 (6), pp. 538-550. Date of Electronic Publication: 2023 Oct 18.

Using mortuary and burial data to place COVID-19 in Lusaka, Zambia within a global context.

Autor: Sheppard RJ; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Watson OJ; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.; Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Pieciak R; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Lungu J; Avencion Limited, Lusaka, Zambia., Kwenda G; Department of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia., Moyo C; Avencion Limited, Lusaka, Zambia., Chanda SL; Zambia National Public Health Institute, Lusaka, Zambia., Barnsley G; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Brazeau NF; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Gerard-Ursin ICG; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Olivera Mesa D; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Whittaker C; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Gregson S; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK.; Manicaland Centre for Public Health Research, Biomedical Research and Training Institute, Harare, Zimbabwe., Okell LC; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., Ghani AC; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK., MacLeod WB; Department of Global Health, Boston University School of Public Health, Boston, MA, USA., Del Fava E; Carlo F. Dondena Centre for Research on Social Dynamics and Public Policy, Bocconi University, Milan, Italy.; Max Planck Institute for Demographic Research, Rostock, Germany., Melegaro A; Carlo F. Dondena Centre for Research on Social Dynamics and Public Policy, Bocconi University, Milan, Italy.; Department of Social and Political Science, Bocconi University, Milano, Italy., Hines JZ; Centers for Disease Control and Prevention, Lusaka, Zambia., Mulenga LB; Zambia Ministry of Health, Lusaka, Zambia., Walker PGT; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, UK. patrick.walker06@imperial.ac.uk., Mwananyanda L; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.; Avencion Limited, Lusaka, Zambia., Gill CJ; Department of Global Health, Boston University School of Public Health, Boston, MA, USA.

Publikováno v: Nature communications [Nat Commun] 2023 Jun 29; Vol. 14 (1), pp. 3840. Date of Electronic Publication: 2023 Jun 29.

Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa.

Autor: Okell LC; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, W2 1PG, UK. l.okell@imperial.ac.uk., Kwambai TK; Centre for Global Health Research (CGHR), Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.; Department of Clinical Sciences, Liverpool School of Tropical Medicine (LSTM), Liverpool, UK., Dhabangi A; College of Health Sciences, Makerere University, Kampala, Uganda., Khairallah C; Department of Clinical Sciences, Liverpool School of Tropical Medicine (LSTM), Liverpool, UK., Nkosi-Gondwe T; Kamuzu University of Health Sciences, Blantyre, Malawi.; Training and Research Unit of Excellence, Blantyre, Malawi., Winskill P; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, W2 1PG, UK., Opoka R; College of Health Sciences, Makerere University, Kampala, Uganda., Mousa A; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, W2 1PG, UK., Kühl MJ; Section for Ethics and Health Economics, Department of Global Public Health and Primary Care, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway., Lucas TCD; Big Data Institute, University of Oxford, Oxford, UK., Challenger JD; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College, London, W2 1PG, UK., Idro R; College of Health Sciences, Makerere University, Kampala, Uganda., Weiss DJ; Malaria Atlas Project, Telethon Kids Institute, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, Australia.; Curtin University, Bentley, Australia., Cairns M; International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK., Ter Kuile FO; Centre for Global Health Research (CGHR), Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.; Department of Clinical Sciences, Liverpool School of Tropical Medicine (LSTM), Liverpool, UK., Phiri K; Kamuzu University of Health Sciences, Blantyre, Malawi.; Training and Research Unit of Excellence, Blantyre, Malawi., Robberstad B; Section for Ethics and Health Economics, Department of Global Public Health and Primary Care, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway., Mori AT; Section for Ethics and Health Economics, Department of Global Public Health and Primary Care, University of Bergen, P.O. Box 7804, 5020, Bergen, Norway. pax_amani@yahoo.com.; Chr. Michelsen Institute, P.O. Box 6033, N-5892, Bergen, Norway. pax_amani@yahoo.com.; Muhimbili University of Health and Allied Sciences, P.O.Box 65001, Dar es Salaam, Tanzania. pax_amani@yahoo.com.

Publikováno v: Nature communications [Nat Commun] 2023 Jan 25; Vol. 14 (1), pp. 402. Date of Electronic Publication: 2023 Jan 25.