Simple Synthesis of a Heterocyclophane Exhibiting Anti‐c‐Met Activity by Acting as a Hatch Blocking Access to the Active Site**.

Autor: Takimoto, Tatsuya, Sasaki, Hideaki, Tsue, Hirohito, Takahashi, Hiroki, MacKerell, Alexander D., Nakamura, Ayumi, Nakano, Katsuya, Okazaki, Eori, Betsuyaku, Tatsuki, Tachibana, Ryosuke, Hioki, Kazuhito, Yoluk, Ozge, Jo, Sunhwan

Publikováno v: Chemistry - A European Journal; 1/21/2021, Vol. 27 Issue 5, p1648-1654, 7p

Simple Synthesis of a Heterocyclophane Exhibiting Anti-c-Met Activity by Acting as a Hatch Blocking Access to the Active Site*.

Autor: Takimoto T; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Sasaki H; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Tsue H; Graduate School of Human and Environmental Studies, Kyoto University, Yoshida Nihonmatsu-cho, Sakyo-ku, Kyoto, 606-8501, Japan., Takahashi H; Graduate School of Human and Environmental Studies, Kyoto University, Yoshida Nihonmatsu-cho, Sakyo-ku, Kyoto, 606-8501, Japan., MacKerell AD Jr; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland Baltimore, 20 Penn Street, Baltimore, Maryland, 21201, USA., Nakamura A; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Nakano K; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Okazaki E; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Betsuyaku T; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Tachibana R; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Hioki K; Faculty of Pharmaceutical Sciences, Kobe Gakuin University, Minatojima, chuo-ku, Kobe, 650-8586, Japan., Yoluk O; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland Baltimore, 20 Penn Street, Baltimore, Maryland, 21201, USA., Jo S; SilcsBio LLC, 20 Penn Street, Baltimore, Maryland, 21201, USA.

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Jan 21; Vol. 27 (5), pp. 1648-1654. Date of Electronic Publication: 2020 Dec 15.