Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Okan Tezcan"'
Autor:
Okan Tezcan, Asmaa Said Elshafei, Karina Benderski, Elena Rama, Maike Wagner, Diana Moeckel, Robert Pola, Michal Pechar, Tomas Etrych, Saskia von Stillfried, Fabian Kiessling, Ralf Weiskirchen, Steffen Meurer, Twan Lammers
Publikováno v:
J Control Release
Journal of Controlled Release
Journal of Controlled Release
Multidrug resistance (MDR) reduces the efficacy of chemotherapy. Besides inducing the expression of drug efflux pumps, chemotherapy treatment alters the composition of the tumor microenvironment (TME), thereby potentially limiting tumor-directed drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241f6ce4fad1ea8db0f15bf0ccaa1d50
https://europepmc.org/articles/PMC7614501/
https://europepmc.org/articles/PMC7614501/
Autor:
Pradipta Ranjan Rauta, Yuri Mackeyev, Keith Sanders, Joseph B.K. Kim, Valeria V. Gonzalez, Yasmin Zahra, Muhammad A. Shohayeb, Belal Abousaida, Geraldine V. Vijay, Okan Tezcan, Paul Derry, Anton V. Liopo, Eugene R. Zubarev, Rickey Carter, Pankaj Singh, Sunil Krishnan
Publikováno v:
Science advances. 8(45)
Coating nanoparticles with stealth epilayers increases circulation time by evading opsonization, macrophage phagocytosis, and reticuloendothelial sequestration. However, this also reduces internalization by cancer cells upon reaching the tumor. We de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee89ab0619fef88fec701fbf0650d6b
https://pubmed.ncbi.nlm.nih.gov/36367938
https://pubmed.ncbi.nlm.nih.gov/36367938
Publikováno v:
Cellular Signalling, 74:109731. Elsevier
Chemoresistance is a multifactorial and complex phenomenon, leading to re-adjustment of several intracellular signaling pathways and expression patterns which compromises the efficacy of cancer drug chemo-therapy. Via comparative analysis of sensitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77eae1b71838cb8c2d1b1a00f2d6f6f
https://pubmed.ncbi.nlm.nih.gov/32758668
https://pubmed.ncbi.nlm.nih.gov/32758668
Autor:
Ufuk Gündüz, Okan Tezcan
Publikováno v:
Biomedicine & Pharmacotherapy. 68:357-364
Chemotherapy is one of the well-known treatments in cancer therapy. The effectiveness of chemotherapy is limited by several factors one of which is the emergence of multidrug resistance (MDR). One of the major mechanisms of MDR is the activity of sev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d37d4fc06e433a63cdca2e53827b57
https://doi.org/10.1016/j.biopha.2014.01.006
https://doi.org/10.1016/j.biopha.2014.01.006
Publikováno v:
Expert Opinion on Drug Delivery
Expert opinion on drug delivery, 13(9), 1199-1202. Taylor & Francis
Expert opinion on drug delivery, 13(9), 1199-1202. Taylor & Francis
Multidrug resistance (MDR) is one of the major factors restricting the efficacy of chemotherapy. Several pathophysiological mechanisms contribute to MDR, including the overexpression of drug efflux pumps. Strategies to overcome MDR have mostly focuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd9ef71a76e6ab2ca378403f0d44208f
https://doi.org/10.1080/17425247.2016.1214570
https://doi.org/10.1080/17425247.2016.1214570