Development of a Course-Based Undergraduate Research Experience to Introduce Drug-Receptor Concepts

Autor: Hollie I. Swanson, Ok-Kyong Park Sarge, Thushani Rodrigo-Peiris, Lin Xiang, Vincent M. Cassone

Publikováno v: Journal of Medical Education and Curricular Development, Vol 2016, Iss 3, Pp 57-66 (2016)

Externí odkaz: https://doaj.org/article/75ffa7a77e674c7eab1b2af4679dee2f

Development of a Course-Based Undergraduate Research Experience to Introduce Drug-Receptor Concepts

Autor: Vincent M. Cassone, Ok-Kyong Park Sarge, Hollie I. Swanson, Thushani Rodrigo-Peiris, Lin Xiang

Publikováno v: Journal of Medical Education and Curricular Development
Journal of Medical Education and Curricular Development, Vol 3 (2016)
Journal of Medical Education and Curricular Development, Vol 2016, Iss 3, Pp 57-66 (2016)

Course-based research experiences (CUREs) are currently of high interest due to their potential for engaging undergraduate students in authentic research and maintaining their interest in science, technology, engineering, and mathematics (STEM) major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374c6a93300e04c3846b61988f4c9db6
https://pubmed.ncbi.nlm.nih.gov/29349318

Transactivation of the Parathyroid Hormone Promoter by Specificity Proteins and the Nuclear Factor Y Complex

Autor: Ok-Kyong Park-Sarge, Alexander P. Alimov, Hartmut H. Malluche, Kevin D. Sarge, Nicholas J. Koszewski

Publikováno v: Endocrinology. 146:3409-3416

We previously identified a highly conserved specificity protein 1 (Sp1) DNA element in mammalian PTH promoters that acted as an enhancer of gene transcription and bound Sp1 and Sp3 proteins present in parathyroid gland nuclear extracts. More recently

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa0022d95e0a15eea1cb59cd016b694
https://doi.org/10.1210/en.2005-0272

Contrasting Mammalian Parathyroid Hormone (PTH) Promoters: Nuclear Factor-Y Binds to a Deoxyribonucleic Acid Element Unique to the Human PTH Promoter and Acts as a Transcriptional Enhancer

Autor: M. Chris Langub, Ok-Kyong Park-Sarge, Hartmut H. Malluche, Alexander P. Alimov, Nicholas J. Koszewski

Publikováno v: Endocrinology. 145:2713-2720

The identification of a highly conserved specificity protein 1 (Sp1) DNA element in mammalian PTH promoters was recently reported. However, the presence of a novel DNA-binding complex was subsequently observed exclusively with the human PTH (hPTH) Sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816a910b8b7e835712962ac3a080b1dc
https://doi.org/10.1210/en.2003-1763

Differential Roles for Signal Transducers and Activators of Transcription 5a and 5b in PRL Stimulation of ERα and ERβ Transcription

Autor: Carlos M. Telleria, Ok Kyong Park-Sarge, Michael Byers, Geula Gibori, Jonna Frasor, Li Yuan Yu-Lee, Kyungsoo Park, Jean Djiane, Toshio Kitamura

Publikováno v: Molecular Endocrinology. 15:2172-2181

PRL has been shown to stimulate mRNA expression of both ERalpha and ERbeta in the rat corpus luteum and decidua of pregnancy. To investigate whether PRL may stimulate ER expression at the level of transcription and which transcription factors may med

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64208c35106f05ad4895d6e3bed92f2
https://doi.org/10.1210/mend.15.12.0745