Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Ok Nam Bae"'
Autor:
Sungjoon Cho, Xiaotong Yang, Kyoung-Jae Won, Vanessa A. Leone, Eugene B. Chang, Grace Guzman, Yeonju Ko, Ok-Nam Bae, Hyunwoo Lee, Hyunyoung Jeong
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTThe gut microbiota affects hepatic drug metabolism. However, gut microbial factors modulating hepatic drug metabolism are largely unknown. In this study, using a mouse model of acetaminophen (APAP)-induced hepatotoxicity, we identified a gut
Externí odkaz:
https://doaj.org/article/44a847d2845a476a9d7eee8f022f66fe
Autor:
Eun-Hye Kim, Sungbin Choi, Donghyun Kim, Han Jin Park, Yiying Bian, Sang Ho Choi, Han Young Chung, Ok-Nam Bae
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Microplastics (MPs) and nanoplastics (NPs) formed from decomposed plastic are increasing environmental threats. Although MPs and NPs exposed through various routes enter the systemic circulation, the potential toxicity of those is
Externí odkaz:
https://doaj.org/article/e342486d8d474a82bc1622d30c85ee98
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-12 (2021)
Abstract Background Expanding biomedical application of anatase titanium dioxide (TiO2) nanoparticles (NPs) is raising the public concern on its potential health hazards. Here, we demonstrated that TiO2 NPs can increase phosphatidylserine (PS) exposu
Externí odkaz:
https://doaj.org/article/cf14fbc4c7f643e49a537d8391a3f60e
Autor:
Gwan-Yeong Lee, Alam Zeb, Eun-Hye Kim, Beomseon Suh, Young-Jun Shin, Donghyun Kim, Kyoung-Won Kim, Yeong-Hwan Choe, Ho-Ik Choi, Cheol-Ho Lee, Omer Salman Qureshi, In-Bo Han, Sun-Young Chang, Ok-Nam Bae, Jin-Ki Kim
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2362-2373 (2020)
The short release half-life of carbon monoxide (CO) is a major obstacle to the effective therapeutic use of carbon monoxide-releasing molecule-2 (CORM-2). The potential of CORM-2-entrapped ultradeformable liposomes (CORM-2-UDLs) to enhance the releas
Externí odkaz:
https://doaj.org/article/17892d56a06e492384130a87cc395e98
Autor:
Kyeong-A Kim, Donghyun Kim, Jeong-Hyeon Kim, Young-Jun Shin, Eun-Sun Kim, Muhammad Akram, Eun-Hye Kim, Arshad Majid, Seung-Hoon Baek, Ok-Nam Bae
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background The blood–brain barrier (BBB) maintains homeostasis of the brain environment by tightly regulating the entry of substances from systemic circulation. A breach in the BBB results in increased permeability to potentially toxic sub
Externí odkaz:
https://doaj.org/article/0447bbe0404c4146a9f179c77d21fb8b
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Silver nanoparticles (AgNP) are widely used in medical practices owing to their distinct antibacterial, antiviral and anticancer activities. However, with increasing use of AgNP, concerns over its potential toxicity are also escal
Externí odkaz:
https://doaj.org/article/866036066d5343fb8779529fe45c39a7
Autor:
Eun-Hye Kim, Eun-Sun Kim, Donggeun Shin, Donghyun Kim, Sungbin Choi, Young-Jun Shin, Kyeong-A Kim, Dabi Noh, Ahmet B. Caglayan, G.K. Rajanikant, Arshad Majid, Ok-Nam Bae
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7495 (2021)
Stroke is one of the leading causes of death and disability worldwide. However, treatment options for ischemic stroke remain limited. Matrix-metalloproteinases (MMPs) contribute to brain damage during ischemic strokes by disrupting the blood-brain ba
Externí odkaz:
https://doaj.org/article/0154d06f866f4fe2ac77f4be5f7ed9e8
Publikováno v:
Journal of Functional Foods, Vol 61, Iss , Pp - (2019)
Curcuma longa (C. longa) has been the subject of intensive research for pleiotropic therapeutic potential. However, except for curcumin, the biological activities of other active ingredients of C. longa are not well known. Here, we demonstrated that
Externí odkaz:
https://doaj.org/article/c9788700f8204a5688e1cd39d8badeee
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2019)
Every year stroke claims more than 6 million lives worldwide. The majority of them are ischemic stroke. Small molecule-based therapeutics for ischemic stroke has attracted a lot of attention, but none has been shown to be clinically useful so far. Hy
Externí odkaz:
https://doaj.org/article/9e1b4a76b46d4cb0bd70897fa3677cab
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2563 (2021)
Isothiazolinone (IT) biocides are potent antibacterial substances commonly used as preservatives or disinfectants, and 2-n-Octyl-4-isothiazolin-3-one (OIT; octhilinone) is a common IT biocide that is present in leather products, glue, paints, and cle
Externí odkaz:
https://doaj.org/article/b2581fd88dfc4dca9f761a4ff7fd10e1