Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Ok Hee Kim"'
Autor:
Byung-Jo Choi, Dosang Lee, Jung Hyun Park, Tae Ho Hong, Ok-Hee Kim, Sang Chul Lee, Kee-Hwan Kim, Ho Joong Choi, Say-June Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9232 (2024)
Elevated metastasis-associated in colon cancer 1 (MACC1) expression in colorectal cancer patients, and high transmembrane 4 L6 family member 5 (TM4SF5) protein expressed on various solid tumors’ surface, are linked to aggressive cancer behavior and
Externí odkaz:
https://doaj.org/article/430b7d0913ee4617abd7ec3cc9c4a552
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8762 (2024)
In this study, we explored the potential of genetically engineered exosomes as vehicles for precise drug delivery in gastric cancer therapy. A novel antitumor strategy using biocompatible exosomes (Ex) was devised by genetically engineering adipose-d
Externí odkaz:
https://doaj.org/article/786446d5a1a64befb82e88edf31a201c
Autor:
Jin Wook Lee, Hyun-Oh Gu, Yunshin Jung, YunJae Jung, Seung-Yong Seo, Jeong-Hee Hong, In-Sun Hong, Dae Ho Lee, Ok-Hee Kim, Byung-Chul Oh
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 910-925 (2023)
Abstract Insulin resistance is a major contributor to the pathogenesis of several human diseases, including type 2 diabetes, hypertension, and hyperlipidemia. Notably, insulin resistance and hypertension share common abnormalities, including increase
Externí odkaz:
https://doaj.org/article/2fac70ae79ad4c3b85aa0544c74ee1f5
Cutting-Edge HEK293T Protein-Integrated Lipid Nanostructures: Boosting Biocompatibility and Efficacy
Autor:
Jung-Hyun Park, Cheng-Zhe Bai, Jeong-Hun Kwak, Ho-Joong Choi, Dosang Lee, Ha-Eun Hong, Ok-Hee Kim, Say-June Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3294 (2024)
Recently, artificial exosomes have been developed to overcome the challenges of natural exosomes, such as production scalability and stability. In the production of artificial exosomes, the incorporation of membrane proteins into lipid nanostructures
Externí odkaz:
https://doaj.org/article/ce0f4f7f003e43f6a7d63b163d934b17
Autor:
Hye-Eun Choi, Dong Young Kim, Mi Jin Choi, Jea Il Kim, Ok-Hee Kim, Jinwook Lee, Eunhui Seo, Hyae Gyeong Cheon
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Tranilast, an anti-allergic drug used in the treatment of bronchial asthma, was identified as an inhibitor of the transcription factor Forkhead box O-1 (FoxO-1) by high throughput chemical library screening in the present study. Based on Fox
Externí odkaz:
https://doaj.org/article/561a5155047647578fc64499f7184665
Autor:
Min Joo Kim, Hwan Hee Kim, Young Shin Song, Ok-Hee Kim, Kyungho Choi, Sujin Kim, Byung-Chul Oh, Young Joo Park
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 2, Pp 447-454 (2021)
Background Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland. Methods DE
Externí odkaz:
https://doaj.org/article/3b007b603bb84b5d91b939a0e5d3af48
Autor:
Tae Ho Hong, M. T. Jeena, Ok-Hee Kim, Kee-Hwan Kim, Ho Joong Choi, Kyung Hee Lee, Ha-Eun Hong, Ja-Hyoung Ryu, Say-June Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Currently, there is no appropriate treatment option for patients with sorafenib-resistant hepatocellular carcinoma (HCC). Meanwhile, pronounced anticancer activities of newly-developed mitochondria-accumulating self-assembly peptides (Mito-F
Externí odkaz:
https://doaj.org/article/e81d4952bba346ec8d93be85be85566a
Autor:
Kwang Yeol Paik, Kee-Hwan Kim, Jung Hyun Park, Jae Im Lee, Ok-Hee Kim, Ha-Eun Hong, Haeyeon Seo, Ho Joong Choi, Joseph Ahn, Tae Yun Lee, Say-June Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 3, Pp 438-449 (2020)
Regenerative medicine: Training stem cells to fix liver fibrosis A mixture of molecules produced by genetically modified stem cells could help repair the damage associated with liver fibrosis. Fat-derived adipose stem cells (ASCs) secrete proteins an
Externí odkaz:
https://doaj.org/article/224634bd44d04f0b9d51c325a96398c0
Autor:
Jae-Ho Lee, Younghoon Go, Do-Young Kim, Sun Hee Lee, Ok-Hee Kim, Yong Hyun Jeon, Taeg Kyu Kwon, Jae-Hoon Bae, Dae-Kyu Song, Im Joo Rhyu, In-Kyu Lee, Minho Shong, Byung-Chul Oh, Christopher Petucci, Jeen-Woo Park, Timothy F. Osborne, Seung-Soon Im
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 238-252 (2020)
Obesity: Possible protective enzyme identified An enzyme that limits the build-up of reactive oxygen species (ROS) in fat cells protects mice against metabolic stress during a high-fat diet. Calorie overload leads to high levels of damaging ROS in th
Externí odkaz:
https://doaj.org/article/106facf445dc4fc98d23964a4547c840
Autor:
Ho Joong Choi, Suk Joon Cho, Ok-Hee Kim, Jin Sook Song, Ha-Eun Hong, Sang Chul Lee, Kee-Hwan Kim, Sang Kuon Lee, Young Kyoung You, Tae Ho Hong, Eun Young Kim, Jung Hyun Park, Gun Hyung Na, Dong Do You, Jae Hyun Han, Jae Woo Park, Bong Jun Kwak, Tae Yun Lee, Joseph Ahn, Hwan Hee Lee, Seung Kyu Kang, Kyu-Seok Hwang, Jae-Kyung Jung, Kwan-Young Jung, Say-June Kim
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Although methyl-tertiary butyl ether (MTBE) is the only clinical topical agent for gallstone dissolution, its use is limited by its side effects mostly arising from a relatively low boiling point (55 °C). In this study, we develo
Externí odkaz:
https://doaj.org/article/cae19a5cb78244229e3cfe761383420c