Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ok Cheol Jeon"'
Autor:
Jeong Uk Choi, Sojung Lee, Dong Soo Lee, Jooho Park, Youngro Byun, Ok-Cheol Jeon, Farzana Alam, Jin Woo Park, Foyez Mahmud, Ruby Maharjan
Publikováno v:
Journal of Controlled Release. 284:160-170
There is a growing interest in preclinical research to consider low-dose metronomic chemotherapy as antiangiogenic cancer treatment. Oral metronomic therapy, in particular, has shown much promise with its ease of daily administration and higher thera
Autor:
Ji Won Kim, Seung Woo Chung, Ok Cheol Jeon, Hanul Lee, Young Seok Cho, Seong Who Kim, Seho Kweon, Beom Suk Lee, In San Kim, Sang Yoon Kim, Youngro Byun, Jeong Uk Choi, Gui Chul Kim, Foyez Mahmud
Publikováno v:
International Journal of Cancer. 141:1912-1920
Chemotherapy have commonly been used in maximum tolerated dose to completely eradicate the cancer. However, such treatments often failed due to the complex and dynamic nature of cancer. Therefore, it has been suggested that cancer should be treated a
Autor:
Kyungjin Kim, Youngro Byun, Taslim A. Al-Hilal, Jisuk Yun, Kwangmeyung Kim, Hwajung Nam, Ok Cheol Jeon, Jinha Hwang, Jooho Park
Publikováno v:
Journal of Medicinal Chemistry. 59:10520-10529
Heparin and low molecular weight heparins (LMWHs) have been the drug of choice for the treatment or the prevention of thromboembolic disease. Different methods are employed to prepare the LMWHs that are clinically approved for the market currently. I
Publikováno v:
International Journal of Nanomedicine
INTERNATIONAL JOURNAL OF NANOMEDICINE(11)
INTERNATIONAL JOURNAL OF NANOMEDICINE(11)
Rudra Pangeni,1,* Sang Won Choi,1,* Ok-Cheol Jeon,2 Youngro Byun,3 Jin Woo Park1 1Department of Pharmacy, College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Muan-gun, 2Pharosgen R&D Center, Asan Institute for Life
Autor:
Seung Woo Chung, Seong Who Kim, Ok Cheol Jeon, Youngro Byun, Sang Yoon Kim, Julia Byun, In San Kim, Jeong Uk Choi, Beom Seok Lee
Publikováno v:
Biomaterials. 94:1-8
Existence of the genomically and epigenomically diverse subclones in a tumor severely limits the therapeutic efficacy of targeted agents. To overcome such a limitation, we prepared a novel targeted prodrug, EMC-DEVD-S-DOX, which comprises two importa
Autor:
Raouf Kechrid, Magdalena Swierczewska, Seulki Lee, Ogyi Park, Kang Choon Lee, Youngro Byun, Hana Eom, Kwangmeyung Kim, Sung Mook Lim, Panagiotis Mastorakos, Ok Cheol Jeon, Choong Eun Lee, Tae Hyung Kim, Bin Gao, Jong-Sung Park, Yumin Oh, Sei Kwang Hahn, James P. Hamilton, Clark Zhang, Justin Hanes, Dong-Gyu Jo, Martin G. Pomper
Publikováno v:
Hepatology. 64:209-223
Liver fibrosis is a common outcome of chronic liver disease that leads to liver cirrhosis and hepatocellular carcinoma. No US Food and Drug Administration-approved targeted antifibrotic therapy exists. Activated hepatic stellate cells (aHSCs) are the
Publikováno v:
Journal of Nanoscience and Nanotechnology. 16:2061-2064
To prepare orally available oxaliplatin (OXA), nanocomplexes were formed by ionic conjugation of OXA with the deoxycholic acid derivative, Nalpha-deoxycholy-L-lysyl-methylester (DCK), as an oral absorption enhancer. We characterized the DCK-conjugate
Autor:
Seung Woo Chung, Hak-Soo Kim, Seung Rim Hwang, Hu-Song Zhang, Ok-Cheol Jeon, Youngro Byun, Min-Soo Kang, Boo-Hyun Kang, Taslim A. Al-Hilal, Sang Yoon Kim, Geum-Hee Kwon, Farzana Alam, Joo-Young Lee, Seo-Ho Shin
Publikováno v:
Drug Development and Industrial Pharmacy. 42:1247-1257
Context: As a class of angiogenesis inhibitors, heparin conjugates have shown significant effectiveness in several studies. Objectives: The purpose of our current study is to evaluate the effectiveness and safety of infusing the conjugate of low mole
Publikováno v:
Journal of Applied Toxicology. 36:76-93
The preclinical safety of a newly developed oral anticoagulant, the low molecular weight heparin-deoxycholate conjugate (OH09208), was evaluated by a comprehensive evaluating program in compliance with standard guidelines. The single dose oral toxici
Autor:
Krishna, Ohm Divyam1, Ok Cheol Jeon2,3, Kim, Kwangmeyung4, Byun, Youngro1, Hyun Tae Moon2 htmoon@mediplex.co.kr
Publikováno v:
Journal of Biomaterials Science -- Polymer Edition. Apr2010, Vol. 21 Issue 6/7, p789-802. 14p. 2 Diagrams, 2 Charts, 5 Graphs.