Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Ojas A. Namjoshi"'
Autor:
Martyna Szpakowska, Ann M. Decker, Max Meyrath, Christie B. Palmer, Bruce E. Blough, Ojas A. Namjoshi, Andy Chevigné
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/9baff80a82e64e09b19895b42efeeb61
Autor:
Young Yun Jung, Chakrabhavi Dhananjaya Mohan, Huiyan Eng, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Kanchugarakoppal S. Rangappa, Gautam Sethi, Alan Prem Kumar, Kwang Seok Ahn
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 891 (2022)
Epithelial-mesenchymal transition (EMT) is a crucial process in which the polarized epithelial cells acquire the properties of mesenchymal cells and gain invasive properties. We have previously demonstrated that manganese superoxide dismutase (MnSOD)
Externí odkaz:
https://doaj.org/article/55495811afd3435d9ed2e957d38bef05
Autor:
Alexandria M. Hudson, Gavin M. Lockard, Ojas A. Namjoshi, Joseph W. Wilson, Katie S. Kindt, Bruce E. Blough, Allison B. Coffin
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Hearing loss is the third most common chronic health condition in the United States and largely results from damage to sensory hair cells. Major causes of hair cell damage include aging, noise exposure, and medications such as aminoglycoside antibiot
Externí odkaz:
https://doaj.org/article/2e3a74ceab8a41f3a2394c736a244980
Autor:
Young Yun Jung, Jae-Young Um, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Alan Prem Kumar, Kwang Seok Ahn
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4731 (2020)
Matrine, a quinolizidine alkaloid, is commonly employed for treating various viral and inflammatory disorders. Here, we have evaluated matrine for its activity on C-X-C chemokine receptor type 4 (CXCR4) and matrix metalloproteinases (MMP-9/2) express
Externí odkaz:
https://doaj.org/article/51b435aaf5b64edfb2a99b048ca771fc
Autor:
Sun Tae Hwang, Jae-Young Um, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Kwang Seok Ahn
Publikováno v:
Molecules, Vol 25, Iss 6, p 1320 (2020)
Evodiamine (EVO) is an indoloquinazoline alkaloid that exerts its various anti-oncogenic actions by blocking phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt), mitogen-activated protein kinase (MAPK), c-Met, and nuclear factor kappa B (NF-κB
Externí odkaz:
https://doaj.org/article/38fbd2a4cb3e497dad02358f36d9abb2
Autor:
Young Yun Jung, Jong Hyun Lee, Dongwoo Nam, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Jae-Young Um, Gautam Sethi, Kwang Seok Ahn
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Because of the essential role of signal transducer and activator of transcription 3 (STAT3) in proliferation, anti-apoptosis, and chemoresistance of multiple myeloma (MM), we investigated whether icariin, a prenylated flavonol glycoside, inhibits bot
Externí odkaz:
https://doaj.org/article/eefc23d69b774c2b92dade983221b874
Autor:
Na Young Kim, Young Yun Jung, Min Hee Yang, Arunachalam Chinnathambi, Chandramohan Govindasamy, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Kwang Seok Ahn
Publikováno v:
Biochimie. 200
Renal cell carcinoma (RCC), also called kidney cancer, is one of the most common malignancies worldwide, including the United States and China. Because of the characteristics of RCC that are both insidious and largely insensitive to chemo-radiation,
Autor:
Andy Chevigné, Ojas A. Namjoshi, Max Marc Roger Meyrath, Martyna Szpakowska, Christie B. Palmer, Bruce E. Blough, Ann M. Decker
Publikováno v:
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021)
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-3 (2021)
Autor:
Young Yun Jung, Jae-Young Um, Arunachalam Chinnathambi, Chandramohan Govindasamy, Acharan S. Narula, Ojas A. Namjoshi, Bruce E. Blough, Gautam Sethi, Kwang Seok Ahn
Publikováno v:
European Journal of Pharmacology. 928:175113
Withaferin A (WFA), a withanolide, is isolated from plants of Withania somnifera (L.) Dual (Solanaceae), known as Indian ginseng, Indian winter cherry or Ashwagandha. It has been reported to exert multifaceted anti-neoplastic effects. Here, we analyz
Autor:
Ojas A. Namjoshi, Kwang Seok Ahn, Young Yun Jung, Acharan S. Narula, Seung Ho Baek, Bruce E. Blough
Publikováno v:
Life sciences. 284
Aims Tumor cells metastasis as well as proliferation are important factors that can substantially determines the prognosis of cancer. In particular, epithelial–mesenchymal transition (EMT) is key phenomena which can cause tumor cell transition into