Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Oivin Guicherit"'
Autor:
Molly E Boutin, Caroline E Strong, Brittney Van Hese, Xin Hu, Zina Itkin, Yu-Chi Chen, Andrew LaCroix, Ryan Gordon, Oivin Guicherit, Cassiano Carromeu, Srikanya Kundu, Emily Lee, Marc Ferrer
Publikováno v:
SLAS Discovery, Vol 27, Iss 4, Pp 209-218 (2022)
Discovery of therapeutics for neurological diseases is hampered by the lack of predictive in vitro and in vivo models. Traditionally, in vitro assays rely on engineered cell lines grown two-dimensionally (2D) outside a physiological tissue context, w
Externí odkaz:
https://doaj.org/article/8f107b8615374c78b6df830edb6875ba
Autor:
Grace Woodruff, Naomi Phillips, Cassiano Carromeu, Oivin Guicherit, Alistair White, McCay Johnson, Fabian Zanella, Blake Anson, Timothy Lovenberg, Pascal Bonaventure, Anthony W Harrington
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240991 (2020)
Human induced Pluripotent Stem Cells (iPSCs) are a powerful tool to dissect the biology of complex human cell types such as those of the central nervous system (CNS). However, robust, high-throughput platforms for reliably measuring activity in human
Externí odkaz:
https://doaj.org/article/35b57f2d9c9348399512c9991766b55f
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDF - 98K, Effect of PF-2771 on breast cell line proliferation and CIN index analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652ca35bc0435979c3605c86a726b192
https://doi.org/10.1158/1535-7163.22500646.v1
https://doi.org/10.1158/1535-7163.22500646.v1
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDF - 68K, Broad kinase selectivity analysis of PF-2771.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253f654c4558c3806dcf93e433a2f978
https://doi.org/10.1158/1535-7163.22500649.v1
https://doi.org/10.1158/1535-7163.22500649.v1
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDF - 76K, Cell cycle analysis of PF-2771 treatment of MDA-MB-468 tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24af5d4f11f4027dddf41dc971a082af
https://doi.org/10.1158/1535-7163.22500643.v1
https://doi.org/10.1158/1535-7163.22500643.v1
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDF - 238K, Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b06b84227d49fddd46d5a283a4e637
https://doi.org/10.1158/1535-7163.22500652.v1
https://doi.org/10.1158/1535-7163.22500652.v1
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDF - 165K, Comparison of the effect of PF-2771 and a Eg5/KSP inhibitor on the microtubule network.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82c9426cbe1bc40117f67e7c8f21695
https://doi.org/10.1158/1535-7163.22500661
https://doi.org/10.1158/1535-7163.22500661
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDF - 219K, PK/PD/Efficacy model analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50fc44fd82ef42f0a4c62a34107a8e7
https://doi.org/10.1158/1535-7163.22500655.v1
https://doi.org/10.1158/1535-7163.22500655.v1
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
Breast cancer patients with tumors lacking the three diagnostic markers (ER, PR, and HER2) are classified as triple-negative (primarily basal-like) and have poor prognosis because there is no disease-specific therapy available. To address this unmet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173fcfb99ef1e130e33d6aab03ffa08d
https://doi.org/10.1158/1535-7163.c.6536530.v1
https://doi.org/10.1158/1535-7163.c.6536530.v1
Autor:
Brion W. Murray, Jennifer Yang, Anand Sistla, Zhongdong Huang, Chaoting Liu, Mei Cui, Buwen Huang, Oivin Guicherit, Jeffery Fan, Kirk Kozminski, Peter Wells, John Chionis, Christopher Carroll, Meirong Xu, Jill Hallin, Isha Rymer, Alessandra Blasina, Michael Zager, Zhou Zhu, Ricardo Martinez, Pei-Pei Kung
PDf - 114K, Analysis of mouse body weight in the tumor growth models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9f2008290a749088e102f9d72f52db
https://doi.org/10.1158/1535-7163.22500658
https://doi.org/10.1158/1535-7163.22500658