Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Oisín Cappa"'
Autor:
Adam Russell-Hallinan, Oisín Cappa, Lauren Kerrigan, Claire Tonry, Kevin Edgar, Nadezhda Glezeva, Mark Ledwidge, Kenneth McDonald, Patrick Collier, David A. Simpson, Chris J. Watson
Publikováno v:
Cells, Vol 13, Iss 9, p 752 (2024)
Dilated cardiomyopathy (DCM) is the most common cause of heart failure, with a complex aetiology involving multiple cell types. We aimed to detect cell-specific transcriptomic alterations in DCM through analysis that leveraged recent advancements in
Externí odkaz:
https://doaj.org/article/a7cf370415494e2eb326d5f7bf4fe291
Autor:
Oisín Cappa
Publikováno v:
ACHD/Valve disease/Pericardial disease/Cardiomyopathy.
Introduction Dilated cardiomyopathy (DCM) is the most common cause of heart failure (HF), with a complex aetiology including lifestyle and genetic factors involving pathological changes in multiple cardiac cell types. The ability of single-cell RNA s
Autor:
Amy Dumigan, Oisin Cappa, Brenda Morris, Joana Sá Pessoa, Ricardo Calderon‐Gonzalez, Grant Mills, Rebecca Lancaster, David Simpson, Adrien Kissenpfennig, Jose A Bengoechea
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-26 (2022)
Abstract The strategies deployed by antibiotic‐resistant bacteria to counteract host defences are poorly understood. Here, we elucidate a novel host–pathogen interaction resulting in skewing lung macrophage polarisation by the human pathogen Kleb
Externí odkaz:
https://doaj.org/article/2680c8973c77459980aed84318c4934c
Autor:
Eszter Emri, Oisin Cappa, Caoimhe Kelly, Elod Kortvely, John Paul SanGiovanni, Brian S. McKay, Arthur A. Bergen, David A. Simpson, Imre Lengyel
Publikováno v:
Cells, Vol 12, Iss 5, p 773 (2023)
Zinc supplementation has been shown to be beneficial to slow the progression of age-related macular degeneration (AMD). However, the molecular mechanism underpinning this benefit is not well understood. This study used single-cell RNA sequencing to i
Externí odkaz:
https://doaj.org/article/3ed1ecb4cff647cbad6eee0dd785ff03