Výsledky vyhledávání - "Oikonomakos N"

Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors

Autor: Oikonomakos, N, Johnson, L, Acharya, K, Stuart, D, Barford, D, Hajdu, J, Varvill, K, Melpidou, A, Papageorgiou, T, Graves, D

The detailed environment of the essential cofactor pyridoxal 5'-phosphate in glycogen phosphorylase b, resulting from crystallographic refinement at 1.9-A resolution, is described. The pyridoxal ring is buried in a nonpolar site containing three arom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b926349b49ab17a07ddd4a2a1716bd4b
https://ora.ox.ac.uk/objects/uuid:b5d239e7-b008-418e-bf24-936eeaca5167

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The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition

Autor: Lowe, E. D., Martin Noble, Skamnaki, V. T., Oikonomakos, N. G., Owen, D. J., Johnson, L. N.

Publikováno v: EMBO Journal 16:22(Nov1997):6646-6658
Scopus-Elsevier

This is also available in PubMed Central at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1170269 Journal URL: http://www.nature.com/emboj/archive/index.html

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::625e7e4005c4ba0213bb90908d188d98
http://helios-eie.ekt.gr/EIE/handle/10442/2676

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X-Ray Crystallographic Analysis of 2,6-Anhydro-N-Methyl-D-Glycero-D-Ido-Heptonamide - the 1st Example of a Simple Glucose Analog with a Skew Boat Structure

Autor: WATSON, K, MITCHELL, E, JOHNSON, L, SON, J, BICHARD, C, FLEET, G, FORD, P, WATKIN, D, OIKONOMAKOS, N

Publikováno v: Journal of the Chemical Society-Chemical Communications 7(Apr1993):654-656

Single crystal X-ray crystallographic analysis of 2,6-anhydro-N-methyl-D- glycero-D-ido-heptonamide and a crystallographic binding study with glycogen phosphorylase show an unexpected skew boat conformation for the glucose analogue.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3d3a362d525e2818a2ec859c989eadf5
http://helios-eie.ekt.gr/EIE/handle/10442/2847

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Kinetic and modelling studies on the lipase catalysed enantio selective esterification of (+/-)-perillyl alcohol

Autor: Skouridou, V., Chrysina, E. D., Stamatis, H., Oikonomakos, N. G., Kolisis, F. N.

Several lipases were kinetically studied with the aim to exploit their enantioselectivity in the esterification of (S)-(-) and (R)-(+)-perillyl alcohol with decanoic acid. Most of the lipases studied exhibited stereopreference towards the R-enantiome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::2a969f8f3ead9bbd799da40f57123560
http://olympias.lib.uoi.gr/jspui/handle/123456789/7660

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SPECIFIC-INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIRODIKETOPIPERAZINE AT THE ANOMERIC POSITION OF GLUCOPYRANOSE

Autor: Krulle, T, Watson, K, Gregoriou, M, Johnson, L, Crook, S, Watkin, D, Griffiths, R, Nash, R, Tsitsanou, K, Zographos, S, Oikonomakos, N, Fleet, G

Publikováno v: Tetrahedron Letters 36:45(Nov1995):8291-8294

A key intermediate bicyclic lactone 6 allows control of the anomeric configuration of a spirodiketopiperazine of glucopyranose 5 which is a specific inhibitor of glycogen phosphorylase, showing no inhibition of α- and β-glucosidases, α- and β-gal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6d29a70f4aee7a105449c7b4bd058267
http://ora.ox.ac.uk/objects/uuid:d54e26cf-199a-4d50-8d61-6830a54b5688

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