Allele-Specific Knockdown of Mutant Huntingtin Protein via Editing at Coding Region Single Nucleotide Polymorphism Heterozygosities.

Autor: Oikemus SR; Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Pfister EL; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Sapp E; Department of Neurology, Harvard Medical School and MassGeneral Institute for Neurodegenerative Disease, Charlestown, Massachusetts, USA., Chase KO; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Kennington LA; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Hudgens E; Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Miller R; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Zhu LJ; Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Chaudhary A; Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Mick EO; Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Sena-Esteves M; Horae Gene Therapy Center, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Wolfe SA; Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., DiFiglia M; Department of Neurology, Harvard Medical School and MassGeneral Institute for Neurodegenerative Disease, Charlestown, Massachusetts, USA., Aronin N; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.; RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Brodsky MH; Department of Molecular Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

Publikováno v: Human gene therapy [Hum Gene Ther] 2022 Jan; Vol. 33 (1-2), pp. 25-36.

Epigenetic telomere protection by Drosophila DNA damage response pathways.

Autor: Oikemus SR; Program in Gene Function and Expression and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA., Queiroz-Machado J, Lai K, McGinnis N, Sunkel C, Brodsky MH

Publikováno v: PLoS genetics [PLoS Genet] 2006 May; Vol. 2 (5), pp. e71. Date of Electronic Publication: 2006 May 19.