Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Oi Kwan Wong"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/19502ef27dab42e2836d7e76ea91ceb2
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/7c68ccf827644bc89cc27374d7cb9037
Publikováno v:
PLoS Biology, Vol 6, Iss 9, p e232 (2008)
At many promoters, transcription is regulated by simultaneous binding of a protein to multiple sites on DNA, but the structures and dynamics of such transcription factor-mediated DNA loops are poorly understood. We directly examined in vitro loop for
Externí odkaz:
https://doaj.org/article/f2e83208ed75475ba24569445b8e8955
Autor:
Shu-Hui Liu, Dave L. Shelton, Arvind Rajpal, Jaume Pons, Christopher J. O'Donnell, Bora Han, Laura Aschenbrenner, Eugenia Kraynov, Aidong Wu, Dahui Zhou, Wei-Hsien Ho, Oi Kwan Wong, Russell Dushin, Kathy Delaria, Magdalena Dorywalska, Thomas-Toan Tran, Pavel Strop
Trop-2, also known as TACSTD2, EGP-1, GA733-1, and M1S1, is frequently expressed on a variety of human carcinomas, and its expression is often associated with poor prognosis of the diseases. However, it is also present on the epithelium of several no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c22a1405dde1c362d0ec7678f31ed90
https://doi.org/10.1158/1535-7163.c.6538356
https://doi.org/10.1158/1535-7163.c.6538356
Autor:
Shu-Hui Liu, Dave L. Shelton, Arvind Rajpal, Jaume Pons, Christopher J. O'Donnell, Bora Han, Laura Aschenbrenner, Eugenia Kraynov, Aidong Wu, Dahui Zhou, Wei-Hsien Ho, Oi Kwan Wong, Russell Dushin, Kathy Delaria, Magdalena Dorywalska, Thomas-Toan Tran, Pavel Strop
Supplementary Figure S1.RN927C induced mitotic arrest of pancreatic PDX tumors in vivo; Supplementary Figure S2. Unconjugated anti-Trop-2 antibody reduced RN927C in vivo efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2d4431b675b338ae1a2730794a9399
https://doi.org/10.1158/1535-7163.22506306
https://doi.org/10.1158/1535-7163.22506306
Publikováno v:
Cancer Research. 83:1870-1870
CD47/SIRPα axis is an important checkpoint of innate immune system and is often exploited by tumor cells to evade host immune surveillance. In recent years, therapies such as anti-CD47 monoclonal antibodies (mAbs) and SIRPα fusion proteins that tar
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCD47 conveys a ”don’t eat me” signal through the interaction with its ligand signal regulatory protein-alpha (SIRPa) on myeloid cells and blocks macrophage mediated phagocytosis. Tumor cells, which express high level of CD47, exploit
Publikováno v:
Cancer Research. 82:5385-5385
The cluster of differentiation 38 (CD38) is a well validated target for treating multiple myeloma. Although the anti-CD38 monoclonal antibody treatment has resulted in outstanding responses in patients with multiple myeloma, a significant portion of
Publikováno v:
Cancer Research. 82:3430-3430
CD47/SIRPa axis is an important checkpoint of innate immune system, CD47 interacts with its ligand signal regulatory protein-alpha (SIRPa) on myeloid cells, conveys a “don’t eat me” signal and blocks macrophage mediated phagocytosis. Tumor cell
Publikováno v:
Blood. 138:2413-2413
Targeting cluster of differentiation 38 (CD38) with monoclonal antibodies has resulted in outstanding responses in patients with multiple myeloma (MM). However, a significant portion of patients failed to respond and nearly all patients eventually re