Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Oh-Kyu Yoon"'
Autor:
Nicholas Waldron, P Rod Dunbar, Sanjeev Deva, Oh Kyu Yoon, John Ling, Kai-Wen Lin, Dung Thai, Latesh Lad, Ahmed A Othman, Jared M Odegard, Adele Y Wang, Jonathan Nazareno, Edmond Ang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Checkpoint inhibitors targeting the programmed cell death 1 (PD-1)/programmed cell death 1 ligand 1 (PD-L1) pathway are effective therapies in a range of immunogenic cancer types. Blocking this pathway with an oral therapy could benefit pa
Externí odkaz:
https://doaj.org/article/2b728df121a442dc8e3c4516f01ebf5f
Autor:
Dafna Gladman, Vinod Chandran, Oh Kyu Yoon, Jinfeng Liu, Vladislav A Malkov, Kaori L Ito, Yihua Liu, Lene Vestergaard, Mona Trivedi, Angie Hertz
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Objectives The goal of this study was to identify protein and transcriptional biomarkers and pathways associated with baseline disease state, the effect of filgotinib (FIL) treatment on these biomarkers, and to investigate the mechanism of action of
Externí odkaz:
https://doaj.org/article/9c27836f275b4d8487c241567f1373a4
Autor:
Kai Song, Emon Elboudwarej, Xi Zhao, Luting Zhuo, David Pan, Jinfeng Liu, Carrie Brachmann, Scott D Patterson, Oh Kyu Yoon, Marianna Zavodovskaya
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293400 (2023)
Clinical tumor tissues that are preserved as formalin-fixed paraffin-embedded (FFPE) samples result in extensive cross-linking, fragmentation, and chemical modification of RNA, posing significant challenges for RNA-seq-based gene expression profiling
Externí odkaz:
https://doaj.org/article/d6d86ebcc8254852b6756ddcd0ae693f
Autor:
Tracy M. Yamawaki, Daniel R. Lu, Daniel C. Ellwanger, Dev Bhatt, Paolo Manzanillo, Vanessa Arias, Hong Zhou, Oh Kyu Yoon, Oliver Homann, Songli Wang, Chi-Ming Li
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-18 (2021)
Abstract Background Elucidation of immune populations with single-cell RNA-seq has greatly benefited the field of immunology by deepening the characterization of immune heterogeneity and leading to the discovery of new subtypes. However, single-cell
Externí odkaz:
https://doaj.org/article/e6c3edf6b23b4041b41e0ead257ffb4d
Autor:
Hope Rugo, Aditya Bardia, Frederik Marmé, Javier Cortés, Peter Schmid, Delphine Loirat, Olivier Trédan, Eva Ciruelos, Florence Dalenc, Patricia Gómez Pardo, Komal Jhaveri, Monica Motwani, Oh Kyu Yoon, Hao Wang, Wendy Verret, Sara Tolaney
Publikováno v:
Cancer Research. 83:GS1-11
Background: HR+/HER2– mBC, the most common subset of breast cancer, is treated with sequential endocrine therapy + targeted agents followed by sequential single-agent chemotherapy (CT), with increasingly shorter benefit duration with each subsequen
Autor:
Chandran, Vinod, Malkov, Vladislav A., Ito, Kaori L., Yihua Liu, Vestergaard, Lene, Oh Kyu Yoon, Jinfeng Liu, Trivedi, Mona, Hertz, Angie, Gladman, Dafna
Publikováno v:
RMD Open; Dec2023, Vol. 9 Issue 4, p1-12, 12p
Autor:
Xavier Roblin, Adrian Serone, Oh Kyu Yoon, Luting Zhuo, Ethan Grant, Geert R. D'Haens, Rene Galien, Jacky Woo, Jinfeng Liu
Publikováno v:
Inflammatory bowel diseases, 28(8), 1207-1218. John Wiley and Sons Inc.
Background Pro-inflammatory cytokines are dysregulated in Crohn’s disease (CD) and could serve as surrogate markers to improve diagnostic and therapeutic approaches, potentially addressing an unmet need. We profiled circulating biomarkers and whole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9667d994057ee65650c4371d28dc584d
https://pure.amc.nl/en/publications/effects-of-jak1preferential-inhibitor-filgotinib-on-circulating-biomarkers-and-whole-blood-genespathways-of-patients-with-moderately-to-severely-active-crohns-disease(d85f086f-a574-4321-906c-58827389c799).html
https://pure.amc.nl/en/publications/effects-of-jak1preferential-inhibitor-filgotinib-on-circulating-biomarkers-and-whole-blood-genespathways-of-patients-with-moderately-to-severely-active-crohns-disease(d85f086f-a574-4321-906c-58827389c799).html
Autor:
Walter Reinisch, Adrian Serone, Xavier Hébuterne, Tanja Kühbacher, Maria Kłopocka, Xavier Roblin, Jens Brodbeck, Kim Etchevers, René Galien, Ethan Grant, Chantal Tasset, Oh Kyu Yoon, Shiva Zaboli, Séverine Vermeire
Publikováno v:
Tissue Barriers. 11
The validity and relevance of histologic disease activity in Crohn's disease (CD) is unclear, owing to disconnects with endoscopic pathology. Here, we explore relationships between endoscopic, histologic, and molecular activity. This post hoc analysi
Autor:
Kai Song, Oh Kyu Yoon, Luting Zhuo, Emon Elboudwarej, Biao Li, Jillian Boice, Yang Pan, See Phan, Monica Motwani
Publikováno v:
Cancer Research. 83:4392-4392
Background: Antibody-drug conjugates (ADCs) are novel agents linking potent payloads to antibodies targeting antigen-expressing tumors. Sacituzumab govitecan (SG), a Trop-2-directed ADC, is approved for patients with metastatic triple-negative breast
Autor:
Jason Goh, Xavier Roblin, Oh Kyu Yoon, Rene Galien, Geert R. D'Haens, Jacky Woo, Ethan Grant, Adrian Serone, James Lui, Luting Zhuo
Publikováno v:
Posters.