Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Oguzhan Atay"'
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57970 (2013)
Our understanding of dynamic cellular processes has been greatly enhanced by rapid advances in quantitative fluorescence microscopy. Imaging single cells has emphasized the prevalence of phenomena that can be difficult to infer from population measur
Externí odkaz:
https://doaj.org/article/c29ddaef7110408bb918ce1691522212
Autor:
David S. Tsao, Oguzhan Atay, Tim M. Townes, Spencer G. Kuper, Frederick D. Goldman, Brian P. Landry, Kevin M. Pawlik, Devon Chandler-Brown, Akila Subramaniam, Vivien A. Sheehan, Patrick P. Ye, Erik Westin, Jennifer Hoskovec, Brian Alford
BackgroundSickle cell disease (SCD) and beta thalassemia (β-thalassemia) are among the most common and severe genetically inherited disorders in the world. Although the maternal carrier status of these beta hemoglobinopathies is screened as a part o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d63b6f5d0404a4f1e30cbfb06e7240b0
https://doi.org/10.1101/2021.09.02.21262837
https://doi.org/10.1101/2021.09.02.21262837
Publikováno v:
Cancer Research. 82:526-526
As novel cancer treatments become available, the need to quickly and accurately evaluate whether these treatments are effective remains unaddressed. Obtaining earlier feedback on the efficacy of a cancer therapy could prevent a poor treatment outcome
There is currently an urgent unmet need to increase coronavirus disease 2019 (COVID-19) testing capability to effectively respond to the COVID-19 pandemic. However, the current shortage in RNA extraction reagents as well as limitations in qPCR protoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a323b7e5ec1d5261b1bad9095909322
Autor:
Oguzhan Atay, Jan M. Skotheim
Publikováno v:
The Journal of Cell Biology
Recent studies show that MAPK pathways perform exquisite spatial and temporal signal processing. This review discusses the mechanisms that process dynamic inputs into graded output responses, the role of positive and negative feedbacks, and feedforwa
Autor:
Samuel Greenberg, Amy B. Nguyen, Vivien A. Sheehan, Celeste K. Kanne, Oguzhan Atay, Rahul Shukla, Nelda Itzep, David S. Tsao, Brian P. Landry, Prem N. Arora, Rani Sharma, Sukrit Silas
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
Next-generation DNA sequencing is currently limited by an inability to accurately count the number of input DNA molecules. Molecular counting is particularly needed when accurate quantification is required for diagnostic purposes, such as in single g
Autor:
Rahul Shukla, Oguzhan Atay, Amy B. Nguyen, Prem N. Arora, Sukrit Silas, Vivien A. Sheehan, Nelda Itzep, Brian P. Landry, Celeste K. Kanne, David S. Tsao, Rani Sharma
Next-generation DNA sequencing is currently limited by an inability to count the number of input DNA molecules. Molecular counting is particularly needed when accurate quantification is required for diagnostic purposes, such as in single-gene non-inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ca35ce0fa84f002c61b5849748555b4
https://doi.org/10.1101/597732
https://doi.org/10.1101/597732
Publikováno v:
Cell Systems. 3:121-132
SummaryCellular decisions are made by complex networks that are difficult to analyze. Although it is common to analyze smaller sub-networks known as network motifs, it is unclear whether this is valid, because these motifs are embedded in complex lar
Autor:
Jan M. Skotheim, Oguzhan Atay
Publikováno v:
Molecular Biology of the Cell
Cells make decisions to differentiate, divide, or apoptose based on multiple signals of internal and external origin. These decisions are discrete outputs from dynamic networks comprised of signaling pathways. Yet the validity of this decomposition o
Publikováno v:
Blood. 132:2369-2369
Introduction: Over 300,000 infants are born with sickle cell disease (SCD) every year worldwide, including at least 1,000 in the US. Prenatal diagnosis by amniocentesis or chorionic villus sampling is available; but high cost, invasiveness, and risk