Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ogun Sercan"'
Publikováno v:
World Cancer Research Journal, Vol 8 (2021)
Objective: Chronic Myeloid Leukemia (CML) is a myeloproliferative disorder characterized by the chromosomal translocation t(9;22) encoding for the Bcr/Abl fusion gene. Secreted Frizzled Related Protein (sFRP) gene products are antagonists of Wnt sign
Externí odkaz:
https://doaj.org/article/95f334ae0d8d43e583046339f24ef1b2
Publikováno v:
Tumor Biology, Vol 39 (2017)
Chronic myeloid leukemia is a clonal myeloproliferative disorder that arises from the neoplastic transformation of the hematopoietic stem cell, in which the Wnt/β-catenin signaling pathway has been demonstrated to play an important role in disease p
Externí odkaz:
https://doaj.org/article/c8ad666f309044e6a523c47aa161ad8f
Publikováno v:
Gene. 854
Dishevelled (Dvl) is a scaffold protein that transmits Wnt signals to downstream effectormolecules via both canonical and non-canonical Wnt signaling pathways. Deregulatedactivation of Dvl proteins has been reported in various solid tumors. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa321f05faf6d7d01f5a92d39634eb4b
https://pubmed.ncbi.nlm.nih.gov/36509295
https://pubmed.ncbi.nlm.nih.gov/36509295
Autor:
Melek Pehlivan, Hakki Ogun Sercan
Publikováno v:
Cukurova Medical Journal. 46:318-324
Amaç: Bu çalışmada blastik fazda farklı hücre serilerinde tutulum gösteren iki farklı Ph (+) kronik miyeloid lösemi (KML) hücre hattında, Wnt sinyal yolağı ana oyuncuları olan Wnt ve Frizzled genlerinin ifade farklılıklarının incele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28810396bc52bc790402352063ed0461
https://doi.org/10.17826/cumj.795833
https://doi.org/10.17826/cumj.795833
Autor:
Hatice Ilayhan Karahan Coven, Mustafa Soyöz, Zeynep Yüce, Burcu Çerçi, Hakki Ogun Sercan, Melek Pehlivan
Publikováno v:
Молекулярная биология. 54:626-633
Chronic myeloid leukemia is a clonal hematopoietic stem cell disease characterized by myeloid expansion. The hallmark of the disease is the Philadelphia chromosome, which results in the formation of the BCR-ABL oncogene, a tyrosine kinase that is inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60b01318d582266c79b8c9b19c02a48
https://doi.org/10.31857/s002689842004014x
https://doi.org/10.31857/s002689842004014x
Background: Wnt signaling cascades play important roles in cell fate decisions and their deregulation has been documented in many diseases, including malignant tumors and leukemia. One mechanism of aberrant Wnt signaling is the silencing of Wnt inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efff8ec114a9ab6284eb9dea149d67e2
https://avesis.deu.edu.tr/publication/details/8a61ae8f-3f60-4177-94b3-1d8ec5ec5198/oai
https://avesis.deu.edu.tr/publication/details/8a61ae8f-3f60-4177-94b3-1d8ec5ec5198/oai
Publikováno v:
Turkish Journal of Hematology, Vol 29, Iss 4, Pp 348-353 (2012)
OBJECTIVE: At present in Turkey, centers that are able to give reliable RQ-PCR BCR-ABL results are limited in number. We aimed to describe a cost-effective, in-house method for BCR-ABL quantification and to illustrate an example for RQ-PCR validation
Externí odkaz:
https://doaj.org/article/21c998a811f349f49f1f84b6ac3cade5
Autor:
Melek Pehlivan, Halil Ateş, Hakki Ogun Sercan, Hatice Ilayhan Karahan Coven, Tülay Kiliçaslan Ayna, Mustafa Soyöz, Burcu Çerçi, Zeynep Yüce
Publikováno v:
Volume: 27, Issue: 3 315-321
SDÜ Tıp Fakültesi Dergisi
SDÜ Tıp Fakültesi Dergisi
Amaç: Kronik Miyeloid Lösemi (KML), hematopoetik kök hücreden (HKH) köken alan miyeloproliferatif bir hastalıktır. MikroRNA'lar, transkripsiyon sonrası gen ekspresyonunu düzenlenleyen küçük kodlamayan RNA’lardır. miRNA’lar KML’nin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8ee43586bb26d524fb6bc214e453d6
https://avesis.deu.edu.tr/publication/details/22f23a65-dcfc-4d18-874d-326beaee365b/oai
https://avesis.deu.edu.tr/publication/details/22f23a65-dcfc-4d18-874d-326beaee365b/oai
Publikováno v:
Volume: 34, Issue: 3 271-278
Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi
Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi
Objective: Chronic Myeloid Leukemia (CML) is a clonal myeloproliferative disease of hematopoietic stem cell (HKH) origin. Along with the Bcr-Abl chimeric gene in KML, other additional mutations and epigenetic modifications are necessary for the disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75469bd62becba7e3cf5a0bc232dc359
https://doi.org/10.5505/deutfd.2020.16362
https://doi.org/10.5505/deutfd.2020.16362
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