Wnt/β-catenin signaling pathway inhibitors, glycyrrhizic acid, solanine, polyphyllin I, crocin, hypericin, tubeimoside-1, diosmin, and rutin in medicinal plants have better binding affinities and anticancer properties: Molecular docking and ADMET study.

Autor: Egbuna C; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR) University of Port-Harcourt Port Harcourt Nigeria.; Department of Biochemistry, Faculty of Science University of Port Harcourt Port Harcourt Nigeria.; Department of Biochemistry, Faculty of Natural Sciences Chukwuemeka Odumegwu Ojukwu University Uli Nigeria., Patrick-Iwuanyanwu KC; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR) University of Port-Harcourt Port Harcourt Nigeria.; Department of Biochemistry, Faculty of Science University of Port Harcourt Port Harcourt Nigeria., Onyeike EN; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR) University of Port-Harcourt Port Harcourt Nigeria.; Department of Biochemistry, Faculty of Science University of Port Harcourt Port Harcourt Nigeria., Uche CZ; Department of Medical Biochemistry and Molecular Biology, Faculty of Basic Medical Sciences University of Nigeria Nsukka Nigeria., Ogoke UP; Biostatistics and Computation Unit, Department of Mathematics and Statistics University of Port Harcourt Port Harcourt Nigeria., Riaz M; Department of Allied Health Sciences University of Sargodha Sargodha Pakistan., Ibezim EN; Department of Biochemistry, Faculty of Natural Sciences Chukwuemeka Odumegwu Ojukwu University Uli Nigeria., Khan J; Department of Medical Laboratory Sciences, College of Applied Medical Sciences Majmaah University Al Majmaah Saudi Arabia.; Health and Basic Sciences Research Center Majmaah University Al Majmaah Saudi Arabia., Adedokun KA; Department of Immunology Roswell Park Comprehensive Cancer Center Buffalo New York USA., Imodoye SO; Department of Oncological Sciences, Huntsman Cancer Institute University of Utah Salt Lake City Utah USA., Bello IO; Department of Biological Sciences Southern Illinois University Edwardsville Edwardsville Illinois USA., Awuchi CG; School of Natural and Applied Sciences Kampala International University Kampala Uganda.

Publikováno v: Food science & nutrition [Food Sci Nutr] 2023 May 04; Vol. 11 (7), pp. 4155-4169. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).