Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ofir Regev"'
Publikováno v:
Bioconjugate Chemistry. 30:2909-2916
Conjugation of the prokaryotic ubiquitin-like protein (Pup) to cellular proteins tags these proteins for degradation by a proteasome in actinobacteria. To study the Pup-proteasome system in in vitro biochemical assays, Pup-tagged (i.e., pupylated) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df97814744bddfd1c52f2bdaf0037398
https://doi.org/10.1021/acs.bioconjchem.9b00611
https://doi.org/10.1021/acs.bioconjchem.9b00611
Publikováno v:
Journal of Molecular Biology. 428:4143-4153
Pupylation, the bacterial equivalent of ubiquitylation, involves the conjugation of a prokaryotic ubiquitin-like protein (Pup) to protein targets. In contrast to the ubiquitin system, where many ubiquitin ligases exist, a single bacterial ligase, Paf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8652db4d73d5f1b9596a36709c15ed75
https://doi.org/10.1016/j.jmb.2016.07.021
https://doi.org/10.1016/j.jmb.2016.07.021
Publikováno v:
Journal of molecular biology. 430(5)
The Pup-proteasome system (PPS) is a prokaryotic tagging and degradation system analogous in function to the ubiquitin-proteasome system (UPS). Like ubiquitin, Pup is conjugated to proteins, tagging them for proteasomal degradation. However, in the P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e34695f7b90c3731e5acb8234bdc9e
https://pubmed.ncbi.nlm.nih.gov/29397952
https://pubmed.ncbi.nlm.nih.gov/29397952
Autor:
Yifat Elharar, Maayan Korman, Eyal Gur, Ofir Regev, Shai Schlussel, Nir Hecht, Nimrod Silberberg
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1864(12)
Intracellular proteolysis is critical for the proper functioning of all cells, owing to its involvement in a wide range of processes. Because of the destructive nature of protein degradation, intracellular proteolysis is restricted by control mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cb79e97ddc41080ded858010a7ae0d
https://pubmed.ncbi.nlm.nih.gov/28887055
https://pubmed.ncbi.nlm.nih.gov/28887055
Publikováno v:
The FEBS journal. 282(21)
Bacteria belonging to the phyla Actinobacteria and Nitrospira possess proteasome cores homologous to the eukaryotic 20S proteasome particle. In these bacteria, the cytoplasmic signal for proteasomal degradation is a small protein termed Pup (prokaryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b10d3072d617a7dd317585d8d86608
https://pubmed.ncbi.nlm.nih.gov/26277445
https://pubmed.ncbi.nlm.nih.gov/26277445