Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents.

Autor: Sergei Perov, Ofir Lidor, Nir Salinas, Nimrod Golan, Einav Tayeb-Fligelman, Maya Deshmukh, Dieter Willbold, Meytal Landau

Publikováno v: PLoS Pathogens, Vol 15, Iss 8, p e1007978 (2019)

Curli amyloid fibrils secreted by Enterobacteriaceae mediate host cell adhesion and contribute to biofilm formation, thereby promoting bacterial resistance to environmental stressors. Here, we present crystal structures of amyloid-forming segments fr

Externí odkaz: https://doaj.org/article/83c99c52c5774ca1866971d3d107d047

Introduction of a putative biocontrol agent into a range of phytoplasma- and liberibacter-susceptible crop plants

Autor: Vered Naor, Dor Hamershlak, Eduard Belausov, Nofar Shoshana, Ofir Bahar, Einat Zchori-Fein, Netta Mozes-Daube, Lilach Iasur-Kruh, Ofir Lidor, Tirtza Zahavi, O. Dror

Publikováno v: Pest Management Science. 74:811-819

BACKGROUND Phytoplasma, the causative agent of Bois Noir disease of grapevines, are vectored by the planthopper Hyalesthes obsoletus (Hemiptera: Cixiidae). A Dyella-like bacterium (DLB) isolated from H. obsoletus inhibits the growth of Spiroplasma me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::35ec7d4ebcbb07f29d32c0fc771c72ff
https://doi.org/10.1002/ps.4775

Frateuria defendens sp. nov., bacterium isolated from the yellows grapevine’s disease vector Hyalesthes obsoletus

Autor: Vered Naor, Diego Santos-Garcia, Einat Zchori-Fein, Lilach Iasur-Kruh, Netta Mozes-Daube, Ofir Lidor, Ofir Bahar, Eyal Cohen

Publikováno v: International Journal of Systematic and Evolutionary Microbiology
International Journal of Systematic and Evolutionary Microbiology, Microbiology Society, 2019, 69 (5), pp.1281-1287. ⟨10.1099/ijsem.0.003305⟩

A Dyella -like bacterium was previously isolated from the planthopper Hyalesthes obsoletus (Hemiptera). Based on its 16S rRNA gene sequence, strain DHoT was assigned to the family Rhodanobacteraceae with Dyella and Frateuria as its closest relatives.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbc599e687aee2c97c541a7f0d89709
https://hal.archives-ouvertes.fr/hal-03270223/document

Novel in silico to in vitro schema: new antibiotic exploration approach

Autor: Anat Greental, ofir lidor

Publikováno v: Molecules & Medicinal Chemistry.

Docking prediction analysis is a computerized model which can aid in developing new potential bacterial targets for antibiotics. Trying to find a molecule with a high potential binding with its macromolecule (protein) is challenging. The bacterial cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac53c84e2783a3a3945f319ad45e4ccb
https://doi.org/10.14800/mmc.1350