Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ofer Zimmerman"'
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 2 (2023)
Alphaviruses are enveloped, insect-transmitted, positive-sense RNA viruses that infect humans and other animals and cause a range of clinical manifestations, including arthritis, musculoskeletal disease, meningitis, encephalitis, and death. Over the
Externí odkaz:
https://doaj.org/article/565dce3b63d94eada84d807682e54e17
Autor:
Frank J. Lin, Alexa Michelle Altman Doss, Hannah G. Davis-Adams, Lucas J. Adams, Christopher H. Hanson, Laura A. VanBlargan, Chieh-Yu Liang, Rita E. Chen, Jennifer Marie Monroy, H. James Wedner, Anthony Kulczycki, Tarisa L. Mantia, Caitlin C. O’Shaughnessy, Saravanan Raju, Fang R. Zhao, Elise Rizzi, Christopher J. Rigell, Tiffany Biason Dy, Andrew L. Kau, Zhen Ren, Jackson S. Turner, Jane A. O’Halloran, Rachel M. Presti, Daved H. Fremont, Peggy L. Kendall, Ali H. Ellebedy, Philip A. Mudd, Michael S. Diamond, Ofer Zimmerman, Brian J. Laidlaw
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAlthough SARS-CoV-2 vaccines have proven effective in eliciting a protective immune response in healthy individuals, their ability to induce a durable immune response in immunocompromised individuals remains poorly understood. Primary antib
Externí odkaz:
https://doaj.org/article/09d941fbe1f542eca1d74a7632944273
Autor:
Ofer Zimmerman, Peter Olbrich, Alexandra F. Freeman, Lindsey B. Rosen, Gulbu Uzel, Christa S. Zerbe, Sergio D. Rosenzweig, Hye Sun Kuehn, Kevin L. Holmes, David Stephany, Li Ding, Elizabeth P. Sampaio, Amy P. Hsu, Steven M. Holland
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Signal transducer and activator of transcription (STAT1)1 gain of function (GOF) pathogenic variants have been associated with increased levels of phosphorylated STAT1 and STAT1-dependent cellular responses. Delayed dephosphorylation was proposed as
Externí odkaz:
https://doaj.org/article/7451b57e604e4c9b9b380c85439ac3fb
Autor:
Ofer Zimmerman, Lindsey B. Rosen, Muthulekha Swamydas, Elise M. N. Ferre, Mukil Natarajan, Frank van de Veerdonk, Steven M. Holland, Michail S. Lionakis
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare primary immunodeficiency disorder typically caused by biallelic autoimmune regulator (AIRE) mutations that manifests with chronic mucocutaneous candidiasis (CMC) and au
Externí odkaz:
https://doaj.org/article/b2b1458cb3b740d3acfdc1a6ca57be98
Autor:
Pilar Blanco Lobo, Paloma Guisado-Hernández, Isabel Villaoslada, Beatriz de Felipe, Carmen Carreras, Hector Rodriguez, Begoña Carazo-Gallego, Ana Méndez-Echevarria, José Manuel Lucena, Pilar Ortiz Aljaro, María José Castro, José Francisco Noguera-Uclés, Joshua D. Milner, Katelyn McCann, Ofer Zimmerman, Alexandra F. Freeman, Michail S. Lionakis, Steven M. Holland, Olaf Neth, Peter Olbrich
Publikováno v:
JOURNAL OF CLINICAL IMMUNOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
[Purpose] STAT1 gain-of-function (GOF) and dominant-negative (DN) STAT3 syndromes share clinical manifestations including infectious and inflammatory manifestations. Targeted treatment with Janus-kinase (JAK) inhibitors shows promising results in tre
Autor:
Alexa Doss, Chieh-Yu Liang, Jennifer Monroy, James Wedner, Christopher Rigell, Hannah Davis-Adams, Lucas Adams, Peggy Kendall, Michael Diamond, Ofer Zimmerman
Publikováno v:
Clinical Immunology. 250:109463
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice. 9:628-639
Advances in diagnosis of inborn errors of immunity (IEI) and an understanding of the molecular and immunologic mechanisms of these disorders have led to both the development of new therapies and improved approaches to hematopoietic cell transplantati
Autor:
Olaf Neth, Pilar Blanco Lobo, Paloma Guisado Hernández, Isabel Villaoslada Casaled, Beatriz de Felipe Carrillo, Carmen Carreras, Hector Rodriguez, Begoña Carazo-Gallego, Ana Méndez- Echevarria, José Manuel Lucena, Pilar Ortiz Aljaro, María José Castro, José Francisco Noguera-Uclés, Joshua D. Milner, Katelyn McCann, Ofer Zimmerman, Alejandra F. Freeman, Michail S. Lionakis, Steven M. Holland, Peter Olbrich
Purpose: STAT1 gain-of-function (GOF) and dominant negative (DN) STAT3 syndromes share clinical manifestations including infectious and inflammatory manifestations. Targeted treatment with Janus-kinase (JAK) inhibitors show promising results in treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffc500dc19208d6f4cbb0c74d2b4215a
https://doi.org/10.21203/rs.3.rs-1346663/v1
https://doi.org/10.21203/rs.3.rs-1346663/v1
Autor:
Ofer Zimmerman, Alexa Michelle Altman Doss, Paulina Kaplonek, Laura A. VanBlargan, Chieh-Yu Liang, Rita E. Chen, Jennifer Marie Monroy, H. James Wedner, Anthony Kulczycki, Tarisa L. Mantia, Caitlin C. O’Shaughnessy, Hannah G. Davis-Adams, Harry L. Bertera, Lucas J. Adams, Saravanan Raju, Fang R. Zhao, Christopher J. Rigell, Tiffany Biason Dy, Andrew L. Kau, Zhen Ren, Jackson Turner, Jane A. O’Halloran, Rachel M. Presti, Daved H Fremont, Peggy L. Kendall, Ali H. Ellebedy, Galit Alter, Michael S. Diamond
Patients with primary antibody deficiency syndromes (PAD) have poor humoral immune responses requiring immunoglobulin replacement therapy. We followed PAD patients after SARS-CoV-2 vaccination by evaluating their immunoglobulin replacement products a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f04e072f0f688ddbb6e6232969218ad
https://doi.org/10.1101/2022.01.26.22269848
https://doi.org/10.1101/2022.01.26.22269848
Autor:
Ofer Zimmerman, Alexa Michelle Altman Doss, Paulina Kaplonek, Chieh-Yu Liang, Laura A. VanBlargan, Rita E. Chen, Jennifer Marie Monroy, H. James Wedner, Anthony Kulczycki, Tarisa L. Mantia, Caitlin C. O’Shaughnessy, Hannah G. Davis-Adams, Harry L. Bertera, Lucas J. Adams, Saravanan Raju, Fang R. Zhao, Christopher J. Rigell, Tiffany Biason Dy, Andrew L. Kau, Zhen Ren, Jackson S. Turner, Jane A. O’Halloran, Rachel M. Presti, Daved H. Fremont, Peggy L. Kendall, Ali H. Ellebedy, Galit Alter, Michael S. Diamond
Publikováno v:
Cell reports. Medicine. 3(6)
Individuals with primary antibody deficiency (PAD) syndromes have poor humoral immune responses requiring immunoglobulin replacement therapy. We followed individuals with PAD after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinat