Fertility protective effects of Brillantaisia patula leaf extract against cyclophosphamide-induced ovarian damage in Wistar rats

Autor: Olalekan Bukunmi Ogunro, Bankole Emmanuel Ofeniforo

Publikováno v: BMC Biotechnology, Vol 24, Iss 1, Pp 1-14 (2024)

Abstract Background The primary indication of infertility is the incapacity to conceive, and in females, the majority of instances of female infertility stem from ovulation disorders. This study evaluated the female fertility-enhancing effects and sa

Externí odkaz: https://doaj.org/article/9fac4f299b95423d92882539a863f4d6

Assessing the Oxidative Stress Reducing Potential of Spilanthes filicaulis (Schumach & Thonn) Ethyl-Acetate Sub-fractions on Plasmodium berghei Infected Female Mice.

Autor: Ofeniforo BE; Department of Chemical Sciences, Faculty of Natural and Applied Science, Oduduwa University Ipetumodu, Ipetumodu, 220211, Nigeria. Ofeniforobankole@gmail.com.; Department of Biochemistry, Faculty of Life Science, University of Ilorin, Ilorin, 240222, Nigeria. Ofeniforobankole@gmail.com., Nwikwe DC; Department of Biochemistry, Faculty of Life Science, University of Ilorin, Ilorin, 240222, Nigeria.; Department of Chemical Sciences, Faculty of Science, Kings University, Odeomu, 220104, Nigeria., Agada SE; Department of Biotechnology, University of Chester, Chester, England, UK., Balogun EA; Department of Biochemistry, Faculty of Life Science, University of Ilorin, Ilorin, 240222, Nigeria.

Publikováno v: Acta parasitologica [Acta Parasitol] 2024 Oct 02. Date of Electronic Publication: 2024 Oct 02.

Quercetin-3-O-β-D-glucopyranoside-rich fraction demonstrated efficacy against infectious, secretory, and osmotic models of diarrhoeal rats

Autor: Olalekan Bukunmi Ogunro, Emmanuel Bankole Ofeniforo, Aderonke Elizabeth Fakayode

Publikováno v: Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-23 (2023)

Abstract Background The prevalence of diarrhoea remains high despite efforts by governments and NGOs to reverse trend. This study investigated the antidiarrhoeal activity and mechanism of Spondias mombin leaf fraction rich in quercetin-3-O-β-D-gluco

Externí odkaz: https://doaj.org/article/f95d9b82d59c40159cf52cf44e7cef80

Insights into features and lead optimization of novel type 1½ inhibitors of p38α mitogen-activated protein kinase using QSAR, quantum mechanics, bioisostere replacement and ADMET studies

Autor: Joel, Ireoluwa Yinka, Adigun, Temidayo Olamide, Bankole, Olukayode Olusola, Iduze, Mohammed Aminu, AbelJack-Soala, Tamonokorite, ANI, Onyedika Gabriel, Olapade, Elijah Oluwafunto, Dada, Friday Micheal, Adetiwa, Olusola Mercy, Ofeniforo, Bankole Emmanuel, Akanni, Funmilola Olamide

Publikováno v: In Results in Chemistry January 2020 2

Insights into features and lead optimization of novel type 1½ inhibitors of p38α mitogen-activated protein kinase using QSAR, quantum mechanics, bioisostere replacement and ADMET studies

Autor: Ireoluwa Yinka Joel, Temidayo Olamide Adigun, Olukayode Olusola Bankole, Mohammed Aminu Iduze, Tamonokorite AbelJack-Soala, Onyedika Gabriel ANI, Elijah Oluwafunto Olapade, Friday Micheal Dada, Olusola Mercy Adetiwa, Bankole Emmanuel Ofeniforo, Funmilola Olamide Akanni

Publikováno v: Results in Chemistry, Vol 2, Iss , Pp 100044- (2020)

p38α mitogen-activated protein kinase (p38αMAPK) has been implicated in many diseases yet no inhibitor has been approved for therapeutic use. Various inhibitors have been developed with different binding modes, but none has been approved for use du

Externí odkaz: https://doaj.org/article/4cd5681e052c4f81a8126e5576a61377