Dynamic Sumoylation of a Conserved Transcription Corepressor Prevents Persistent Inclusion Formation during Hyperosmotic Stress.

Autor: Oeser ML; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, United States of America.; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America., Amen T; Alexander Grass Center for Bioengineering, Hebrew University of Jerusalem, Jerusalem, Israel.; Department of Cell and Developmental Biology, Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem, Israel., Nadel CM; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America., Bradley AI; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, United States of America., Reed BJ; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America., Jones RD; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America., Gopalan J; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America., Kaganovich D; Department of Cell and Developmental Biology, Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem, Israel., Gardner RG; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, United States of America.; Department of Pharmacology, University of Washington, Seattle, Washington, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2016 Jan 22; Vol. 12 (1), pp. e1005809. Date of Electronic Publication: 2016 Jan 22 (Print Publication: 2016).

Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates.

Autor: Rosenbaum JC; Department of Pharmacology, University of Washington, Seattle, WA 98195, USA., Fredrickson EK, Oeser ML, Garrett-Engele CM, Locke MN, Richardson LA, Nelson ZW, Hetrick ED, Milac TI, Gottschling DE, Gardner RG

Publikováno v: Molecular cell [Mol Cell] 2011 Jan 07; Vol. 41 (1), pp. 93-106.

The ZSWIM8 ubiquitin ligase regulates neurodevelopment by guarding the protein quality of intrinsically disordered Dab1.

Autor: Wang, Guan, Lei, Jing, Wang, Yifeng, Yu, Jiahui, He, Yinghui, Zhao, Weiqi, Hu, Zhechun, Xu, Zhenzhong, Jin, Yishi, Gu, Yan, Guo, Xing, Yang, Bing, Gao, Zhihua, Wang, Zhiping

Publikováno v: Cerebral Cortex; Apr2023, Vol. 33 Issue 7, p3866-3881, 16p

Sequence features governing aggregation or degradation of prion-like proteins.

Autor: Cascarina, Sean M.¹, Paul, Kacy R.¹, Machihara, Satoshi¹, Ross, Eric D.¹ eric.ross@colostate.edu

Publikováno v: PLoS Genetics. 7/13/2018, Vol. 14 Issue 7, p1-27. 27p.

Stress induced nuclear granules form in response to accumulation of misfolded proteins in Caenorhabditis elegans.

Autor: Sampuda, Katherine M.¹, Riley, Mason¹, Boyd, Lynn¹ lynn.boyd@mtsu.edu

Publikováno v: BMC Cell Biology. 4/19/2017, Vol. 18, p1-18. 18p.