SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

Autor: Joyce, M. Gordon, Chen, Wei-Hung, Sankhala, Rajeshwer S., Hajduczki, Agnes, Thomas, Paul V., Choe, Misook, Martinez, Elizabeth J., Chang, William C., Peterson, Caroline E., Morrison, Elaine B., Smith, Clayton, Chen, Rita E., Ahmed, Aslaa, Wieczorek, Lindsay, Anderson, Alexander, Case, James Brett, Li, Yifan, Oertel, Therese, Rosado, Lorean, Ganesh, Akshaya, Whalen, Connor, Carmen, Joshua M., Mendez-Rivera, Letzibeth, Karch, Christopher P., Gohain, Neelakshi, Villar, Zuzana, McCurdy, David, Beck, Zoltan, Kim, Jiae, Shrivastava, Shikha, Jobe, Ousman, Dussupt, Vincent, Molnar, Sebastian, Tran, Ursula, Kannadka, Chandrika B., Soman, Sandrine, Kuklis, Caitlin, Zemil, Michelle, Khanh, Htet, Wu, Weimin, Cole, Matthew A., Duso, Debra K., Kummer, Larry W., Lang, Tricia J., Muncil, Shania E., Currier, Jeffrey R., Krebs, Shelly J., Polonis, Victoria R., Rajan, Saravanan, McTamney, Patrick M., Esser, Mark T., Reiley, William W., Rolland, Morgane, de Val, Natalia, Diamond, Michael S., Gromowski, Gregory D., Matyas, Gary R., Rao, Mangala, Michael, Nelson L., Modjarrad, Kayvon

Publikováno v: In Cell Reports 21 December 2021 37(12)

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SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity.

Autor: Joyce MG; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; Lead contact., Chen WH; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Sankhala RS; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Hajduczki A; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Thomas PV; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Choe M; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Chang W; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Peterson CE; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Martinez E; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA., Morrison EB; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Smith C; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA., Ahmed A; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Wieczorek L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Anderson A; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Chen RE; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA., Case JB; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA., Li Y; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Oertel T; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Rosado L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Ganesh A; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Whalen C; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Carmen JM; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Mendez-Rivera L; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Karch C; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Gohain N; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Villar Z; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., McCurdy D; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Beck Z; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kim J; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Shrivastava S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Jobe O; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Dussupt V; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Molnar S; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Tran U; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Kannadka CB; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Zemil M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Khanh H; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA., Wu W; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA., Cole MA; Trudeau Institute, Inc., Saranac Lake, NY, USA., Duso DK; Trudeau Institute, Inc., Saranac Lake, NY, USA., Kummer LW; Trudeau Institute, Inc., Saranac Lake, NY, USA., Lang TJ; Trudeau Institute, Inc., Saranac Lake, NY, USA., Muncil SE; Trudeau Institute, Inc., Saranac Lake, NY, USA., Currier JR; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Krebs SJ; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Polonis VR; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Rajan S; Antibody Discovery and Protein Engineering (ADPE), BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, USA., McTamney PM; Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Esser MT; Microbial Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Reiley WW; Trudeau Institute, Inc., Saranac Lake, NY, USA., Rolland M; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., de Val N; Center for Molecular Microscopy, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.; Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, USA., Diamond MS; Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA., Gromowski GD; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Matyas GR; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Rao M; U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Michael NL; Center for Infectious Diseases Research, Walter Reed Army Institute of Research, Silver Spring, MD, USA., Modjarrad K; Emerging Infectious Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2021 May 10. Date of Electronic Publication: 2021 May 10.