Study protocol of the DUtch PARkinson Cohort (DUPARC): a prospective, observational study of de novo Parkinson’s disease patients for the identification and validation of biomarkers for Parkinson’s disease subtypes, progression and pathophysiology

Autor: Boertien, Jeffrey M., van der Zee, Sygrid, Chrysou, Asterios, Gerritsen, Marleen J. J., Jansonius, Nomdo M., Spikman, Jacoba M., van Laar, Teus, Verwey, N. A., van Harten, B., Portman, A. T., Langedijk, M. J. H., Oomes, P. G., Jansen, B. J. A. M., van Wieren, T., van den Bogaard, S. J. A., van Steenbergen, W., Duyff, R., van Amerongen, J. P., Fransen, P. S. S., Polman, S. K. L., Zwartbol, R. T., van Kesteren, M. E., Braakhekke, J. P., Trip, J., Koops, L., de Langen, C. J., de Jong, G., Hartono, J. E. S., Ybema, H., Bartels, A. L., Reesink, F. E., Postma, A. G., Vonk, G. J. H., Oen, J. M. T. H., Brinkman, M. J., Mondria, T., Holscher, R. S., van der Meulen, A. A. E., Rutgers, A. W. F., Boekestein, W. A., Teune, L. K., Orsel, P. J. L., Hoogendijk, J. E., van Laar, T.

Publikováno v: BMC neurology, 20(1):245. BioMed Central
BMC Neurology, Vol 20, Iss 1, Pp 1-11 (2020)
BMC Neurology
BMC NEUROLOGY, 20(1):245. BioMed Central Ltd.

Background Parkinson’s Disease (PD) is a heterogeneous, progressive neurodegenerative disorder which is characterized by a variety of motor and non-motor symptoms. To date, no disease modifying treatment for PD exists. Here, the study protocol of t

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