Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Oelfah Patel"'
Autor:
Kwazi Gabuza, Thendo I Mabuda, Oelfah Patel, Noxolo Khuboni, Ruzayda van Aarde, Sylvia Riedel, Nonhlakanipho F Sangweni, Shantal Windvogel, Rabia Johnson, Christo J F Muller
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0297572 (2024)
BackgroundCurrently, it is acknowledged that vitamin E, insulin sensitizers and anti-diabetic drugs are used to manage non-alcoholic fatty liver disease (NAFLD), however, these therapeutic interventions harbour adverse side effects. Pioglitazone, an
Externí odkaz:
https://doaj.org/article/923f5bcac85143f5a913ae59314306e3
Autor:
Oelfah Patel, Christo J. F. Muller, Elizabeth Joubert, Bernd Rosenkranz, Johan Louw, Charles Awortwe
Publikováno v:
Frontiers in Clinical Diabetes and Healthcare, Vol 3 (2022)
Rooibos (Aspalathus linearis), an indigenous South African plant and its major flavonoid, aspalathin, exhibited positive effects on glycemia and dyslipidemia in animal studies. Limited evidence exists on the effects of rooibos extract taken in combin
Externí odkaz:
https://doaj.org/article/0c7231b6a27442e5809bc2b538b12803
Autor:
Amsha Viraragavan, Tarryn Willmer, Oelfah Patel, Albertus Basson, Rabia Johnson, Carmen Pheiffer
Publikováno v:
Adipocyte, Vol 10, Iss 1, Pp 108-118 (2021)
Increased visceral adipose tissue (VAT) is associated with metabolic dysfunction, while subcutaneous adipose tissue (SAT) is considered protective. The mechanisms underlying these differences are not fully elucidated. This study aimed to investigate
Externí odkaz:
https://doaj.org/article/e1b01e42f27d4c9c8b82b1e34cc220a5
Autor:
Oelfah Patel, Christo J F Muller, Elizabeth Joubert, Bernd Rosenkranz, Johan Louw, Charles Awortwe
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251069 (2021)
Oral therapeutics used to treat type 2 diabetes and cardiovascular disease often fail to prevent the progression of disease and their comorbidities. Rooibos (Aspalathus linearis), an endemic South African plant used as an herbal tea, has demonstrated
Externí odkaz:
https://doaj.org/article/5db923952a7d4afbb43dccac2027af97
Autor:
Oelfah Patel, Christo J.F. Muller, Elizabeth Joubert, Bernd Rosenkranz, Malcolm J.C. Taylor, Johan Louw, Charles Awortwe
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
An aspalathin-rich green rooibos extract (Afriplex GRT™) has demonstrated anti-diabetic and hypolipidemic properties, while also moderately inhibiting CYP3A4 activity, suggesting a potential for herb–drug interaction. The present study, therefore
Externí odkaz:
https://doaj.org/article/e5fe5de090904c1faf135eda0e6cc094
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140148 (2015)
One week of treatment with EGF and gastrin (EGF/G) was shown to restore normoglycemia and to induce islet regeneration in mice treated with the diabetogenic agent alloxan. The mechanisms underlying this regeneration are not fully understood. We perfo
Externí odkaz:
https://doaj.org/article/d8cb637ad4bb47d9a37399e647ab686e
Autor:
Oelfah Patel, Christo Muller, Elizabeth Joubert, Johan Louw, Bernd Rosenkranz, Charles Awortwe
Publikováno v:
Molecules, Vol 21, Iss 11, p 1515 (2016)
Rooibos extract, due to its glucose and lipid lowering effects, has potential as a nutraceutical for improvement of metabolic dysfunction. Potential herb-drug interactions as a result of the use of natural products are of increasing concern. Cytochro
Externí odkaz:
https://doaj.org/article/cd2779393196420a83feeb1bebf7133b
Autor:
Carvern Jacobs, Carmen Pheiffer, Johan Louw, Oelfah Patel, Samira Ghoor, Christo J. F. Muller
Publikováno v:
Journal of physiology and biochemistry. 72(1)
Obesity, a complex metabolic disorder, is characterized by mitochondrial dysfunction and oxidative stress. Increased expression of uncoupling protein 2 (UCP2) during obesity is an adaptive response to suppress the production of reactive oxygen specie