Zobrazeno 1 - 10
of 1 212
pro vyhledávání: '"Oefner P"'
Autor:
Md Nur A Alam Siddique, Fabian Kellermeier, Martha Ölke, Mingming Zhao, Konrad Büssow, Peter J. Oefner, Anja Lührmann, Katja Dettmer, Roland Lang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Aconitate decarboxylase-1 (ACOD1) is expressed by activated macrophages and generates itaconate that exerts anti-microbial and immunoregulatory effects. ACOD1-itaconate is essential for macrophage-mediated control of the intracellular pathogen Coxiel
Externí odkaz:
https://doaj.org/article/23f2879e75db4e8f8ffeb227a10843fd
Autor:
Schrod, Stefan, Schäfer, Andreas, Solbrig, Stefan, Lohmayer, Robert, Gronwald, Wolfram, Oefner, Peter J., Beißbarth, Tim, Spang, Rainer, Zacharias, Helena U., Altenbuchinger, Michael
Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often challenged by the fact that the training data comprises only the outcome for the administered treatment, and not f
Externí odkaz:
http://arxiv.org/abs/2201.03448
Autor:
Kathrin Hammon, Kathrin Renner, Michael Althammer, Florian Voll, Nathalie Babl, Sonja-Maria Decking, Peter J. Siska, Carina Matos, Zugey Elizabeth Cárdenas Conejo, Karina Mendes, Friederike Einwag, Heiko Siegmund, Sabine Iberl, Raffaela S. Berger, Katja Dettmer, Rebecca Schoenmehl, Christoph Brochhausen, Wolfgang Herr, Peter J. Oefner, Michael Rehli, Simone Thomas, Marina Kreutz
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
D-2-hydroxyglutarate (D-2-HG) accumulates in primary acute myeloid leukemia (AML) patients with mutated isocitrate dehydrogenase (IDH) and other malignancies. D-2-HG suppresses antitumor T cell immunity but little is known about potential effects on
Externí odkaz:
https://doaj.org/article/10b1b9a9fb744f37b8e904c18044a165
Akademický článek
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Autor:
Spang Rainer, Parson Walther, Niederstätter Harald, Lottaz Claudio, Thieme Marian, Oefner Peter J
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 440 (2009)
Abstract Background The Affymetrix MitoChip v2.0 is an oligonucleotide tiling array for the resequencing of the human mitochondrial (mt) genome. For each of 16,569 nucleotide positions of the mt genome it holds two sets of four 25-mer probes each tha
Externí odkaz:
https://doaj.org/article/2a998dd779594ca2a53facd8c94d7e14
Autor:
Fadi Fadil, Claudia Samol, Raffaela S. Berger, Fabian Kellermeier, Wolfram Gronwald, Peter J. Oefner, Katja Dettmer
Publikováno v:
Metabolites, Vol 14, Iss 6, p 293 (2024)
It was pointed out to us that we had not followed exactly the IROA TruQuant IQQ Workflow Kit protocol in the experimental part of our work [...]
Externí odkaz:
https://doaj.org/article/6b1266c2316e4bb7a4aea0c8ef5a036b
Autor:
Markus P. Schneider, Matthias Schmid, Jennifer Nadal, Vera Krane, Turgay Saritas, Martin Busch, Ulla T. Schultheiss, Heike Meiselbach, Nele Friedrich, Matthias Nauck, Jürgen Floege, Florian Kronenberg, Christoph Wanner, Kai-Uwe Eckardt, Mario Schiffer, Hans-Ulrich Prokosch, Barbara Bärthlein, Andreas Beck, André Reis, Arif B. Ekici, Susanne Becker, Dinah Becker-Grosspitsch, Ulrike Alberth-Schmidt, Birgit Hausknecht, Anke Weigel, Gerd Walz, Anna Köttgen, Ulla T. Schultheiß, Fruzsina Kotsis, Simone Meder, Erna Mitsch, Ursula Reinhard, Elke Schaeffner, Seema Baid-Agrawal, Kerstin Theisen, Hermann Haller, Jan Menne, Martin Zeier, Claudia Sommerer, Johanna Theilinger, Gunter Wolf, Rainer Paul, Thomas Sitter, Antje Börner-Klein, Britta Bauer, Julia Raschenberger, Barbara Kollerits, Lukas Forer, Sebastian Schönherr, Hansi Weissensteiner, Peter Oefner, Wolfram Gronwald
Publikováno v:
Kidney Medicine, Vol 5, Iss 11, Pp 100725- (2023)
Rationale & Objective: Copeptin and Midrange pro-atrial natriuretic peptide (MR-pro-ANP) are associated with outcomes independently of N-terminal pro-brain natriuretic peptide (NT-pro-BNP) in patients with heart failure (HF). The value of these marke
Externí odkaz:
https://doaj.org/article/0c1a61a4ed0a4a61a9aa38484efa3308
Autor:
Christian Schmidl, Wolfgang Herr, Nathalie Babl, Sonja-Maria Decking, Florian Voll, Michael Althammer, Ada Sala-Hojman, Roberta Ferretti, Clarissa Korf, Lisa Schmidleithner, Benedikt Nerb, Carina Matos, Gudrun E Koehl, Peter Siska, Christina Bruss, Fabian Kellermeier, Katja Dettmer, Peter J Oefner, Marvin Wichland, Ines Ugele, Christopher Bohr, Shivapriya Ramaswamy, Timo Heinrich, Christian Herhaus, Marina Kreutz, Kathrin Renner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background & Aims Intratumoral lactate accumulation and acidosis impair T-cell function and antitumor immunity. Interestingly, expression of the lactate transporter monocarboxylate transporter (MCT) 4, but not MCT1, turned out to be prognostic for th
Externí odkaz:
https://doaj.org/article/c03d167b710e4bcd97adb742f3e84064
Autor:
Lisa Kohl, Md Nur A Alam Siddique, Barbara Bodendorfer, Raffaela Berger, Annica Preikschat, Christoph Daniel, Martha Ölke, Elisabeth Liebler‐Tenorio, Jan Schulze‐Luehrmann, Michael Mauermeir, Kai‐Ting Yang, Inaya Hayek, Manuela Szperlinski, Jennifer Andrack, Ulrike Schleicher, Aline Bozec, Gerhard Krönke, Peter J Murray, Stefan Wirtz, Masahiro Yamamoto, Valentin Schatz, Jonathan Jantsch, Peter Oefner, Daniel Degrandi, Klaus Pfeffer, Katja Mertens‐Scholz, Simon Rauber, Christian Bogdan, Katja Dettmer, Anja Lührmann, Roland Lang
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp 1-20 (2022)
Abstract Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever with severe complications and limited treatment options. Here, we identify the enzyme cis‐aconitate decarboxylase 1 (ACOD1 or IRG1) and its product
Externí odkaz:
https://doaj.org/article/1b69987f304e4114b08d5e4633d04bb6
Akademický článek
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