Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Odile Poulain-Godefroy"'
Autor:
Fatou K. Ndiaye, Ana Ortalli, Mickaël Canouil, Marlène Huyvaert, Clara Salazar-Cardozo, Cécile Lecoeur, Marie Verbanck, Valérie Pawlowski, Raphaël Boutry, Emmanuelle Durand, Iandry Rabearivelo, Olivier Sand, Lorella Marselli, Julie Kerr-Conte, Vikash Chandra, Raphaël Scharfmann, Odile Poulain-Godefroy, Piero Marchetti, François Pattou, Amar Abderrahmani, Philippe Froguel, Amélie Bonnefond
Publikováno v:
Molecular Metabolism, Vol 6, Iss 6, Pp 459-470 (2017)
Objectives: Genome-wide association studies (GWAS) have identified >100 loci independently contributing to type 2 diabetes (T2D) risk. However, translational implications for precision medicine and for the development of novel treatments have been di
Externí odkaz:
https://doaj.org/article/34aced17f41e4cc38485bd3672620da0
Autor:
Marie Verbanck, Mickaël Canouil, Audrey Leloire, Véronique Dhennin, Xavier Coumoul, Loïc Yengo, Philippe Froguel, Odile Poulain-Godefroy
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179583 (2017)
Bisphenol A (BPA) exposure has been suspected to be associated with deleterious effects on health including obesity and metabolically-linked diseases. Although bisphenols F (BPF) and S (BPS) are BPA structural analogs commonly used in many marketed p
Externí odkaz:
https://doaj.org/article/ca23a9a6963542488ea477efc41ca2d7
Autor:
Marie Favennec, Benjamin Hennart, Marie Verbanck, Marie Pigeyre, Robert Caiazzo, Violeta Raverdy, Hélène Verkindt, Audrey Leloire, Gilles J Guillemin, Loïc Yengo, Delphine Allorge, Philippe Froguel, François Pattou, Odile Poulain-Godefroy
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158051 (2016)
BACKGROUND:An increase of plasma kynurenine concentrations, potentially bioactive metabolites of tryptophan, was found in subjects with obesity, resulting from low-grade inflammation of the white adipose tissue. Bariatric surgery decreases low-grade
Externí odkaz:
https://doaj.org/article/f87534658c0d4383b6f39027b39681df
Autor:
Gilles Riveau, Odile Poulain-Godefroy, Loïc Dupré, Franck Remoué, Nathalie Mielcarek, Camille Locht, André Capron
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 93, Pp 87-94 (1998)
For the development of vaccine strategies to generate efficient protection against chronic infections such as parasitic diseases, and more precisely schistosomiasis, controlling pathology could be more relevant than controlling the infection itself.
Externí odkaz:
https://doaj.org/article/9f03ef59e26a4abb96f11ad5f374021c
Autor:
Stéphanie Lucas, Solenne Taront, Christophe Magnan, Laurence Fauconnier, Myriam Delacre, Laurence Macia, Anne Delanoye, Claudie Verwaerde, Corentin Spriet, Pasquine Saule, Gautier Goormachtigh, Laurent Héliot, Alain Ktorza, Jamileh Movassat, Renata Polakowska, Claude Auriault, Odile Poulain-Godefroy, James Di Santo, Philippe Froguel, Isabelle Wolowczuk
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40351 (2012)
Although interleukin (IL)-7 is mostly known as a key regulator of lymphocyte homeostasis, we recently demonstrated that it also contributes to body weight regulation through a hypothalamic control. Previous studies have shown that IL-7 is produced by
Externí odkaz:
https://doaj.org/article/34849937db524eed90a4971123e86e33
Autor:
Marion Soichot, Benjamin Hennart, Alaa Al Saabi, Audrey Leloire, Philippe Froguel, Claire Levy-Marchal, Odile Poulain-Godefroy, Delphine Allorge
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25470 (2011)
Indoleamine 2,3-dioxygenase (IDO) catalyzes the first and rate-limiting step of the kynurenine pathway that is an important component of immunomodulatory and neuromodulatory processes. The IDO1 gene is highly inducible by IFN-γ and TNF-α through in
Externí odkaz:
https://doaj.org/article/52ec8e11824640c0a03b8ec73a9f41f4
Autor:
Odile Poulain-Godefroy, Olivier Le Bacquer, Pauline Plancq, Cécile Lecœur, François Pattou, Gema Frühbeck, Philippe Froguel
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
It was recently demonstrated that TLR4 activation via dietary lipids triggers inflammatory pathway and alters insulin responsiveness in the fat tissue during obesity. Here, we question whether other TLR family members could participate in the TLR-med
Externí odkaz:
https://doaj.org/article/2eeaa9dd7005429687a7ea4c914a683e
Autor:
Odile Poulain-Godefroy, Mélina Le Roux, Gwenola Kervoaze, Anais Ollivier, Muriel Pichavant, Philippe Gosset
Publikováno v:
Airway cell biology and immunopathology.
Autor:
Ana Ortalli, Marlène Huyvaert, Amélie Bonnefond, Lorella Marselli, Piero Marchetti, Marie Verbanck, Fatou K. Ndiaye, Julie Kerr-Conte, Raphaël Scharfmann, Emmanuelle Durand, Philippe Froguel, Amar Abderrahmani, Mickaël Canouil, Olivier Sand, Vikash Chandra, François Pattou, Raphaël Boutry, Valérie Pawlowski, Odile Poulain-Godefroy, C. Lecoeur, Iandry Rabearivelo, Clara Salazar-Cardozo
Publikováno v:
Molecular Metabolism, Vol 6, Iss 6, Pp 459-470 (2017)
Molecular Metabolism
Molecular Metabolism
Objectives Genome-wide association studies (GWAS) have identified >100 loci independently contributing to type 2 diabetes (T2D) risk. However, translational implications for precision medicine and for the development of novel treatments have been dis
Autor:
François Pattou, Philippe Froguel, Odile Poulain-Godefroy, Giulia Chinetti, Marie Favennec, Bart Staels, Robert Caiazzo, Audrey Leloire, Benjamin Hennart, Delphine Allorge, Alban Bessede, Abdelilah Arredouani, Loic Yengo, Gilles J. Guillemin, Michel Marre, Marie Pigeyre, Beverley Balkau, Marie Verbanck
Publikováno v:
Obesity. 23:2066-2074
Objective This study characterized the kynurenine pathway (KP) in human obesity by evaluating circulating levels of kynurenines and the expression of KP enzymes in adipose tissue. Methods Tryptophan and KP metabolite levels were measured in serum of