Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Odile Médiani"'
Publikováno v:
Fundamental and Clinical Pharmacology. 19:457-464
The strategy of diuretic drug administration remains to be defined in heart failure as experimental and clinical evidence have clearly established the benefit of neurohormonal blockade. The impact of addition of diuretic treatment to angiotensin-conv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb3686066200748f0c26eda9536c2b4
https://doi.org/10.1111/j.1472-8206.2005.00349.x
https://doi.org/10.1111/j.1472-8206.2005.00349.x
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 309:1160-1166
The purpose of the present study was to determine whether the administration of an antagonist of aldosterone could prevent the fibrosis induced by an acute injection of isoprenaline. Male Wistar rats were submitted to one subcutaneous injection of is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6d5eeceef3b51d25459e5ccf97f1f1
https://doi.org/10.1124/jpet.103.063388
https://doi.org/10.1124/jpet.103.063388
Blockade of β1- and desensitization of β2-adrenoceptors reduce isoprenaline-induced cardiac fibrosis
Autor:
Naïma Hanoun, Fazia Brouri, Françoise Saurini, Paul M. Vanhoutte, Odile Médiani, Philippe Lechat, Michel Hamon
Publikováno v:
European Journal of Pharmacology. 485:227-234
The aim of the present study was to analyse the role of beta(1)- and beta(2)-adrenoceptors in the catecholamine-induced myocardial remodeling, especially the interstitial fibrosis. Wistar rats were subjected to a 2-week chronic isoprenaline administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4368ebf4da010543d1232620cc255efb
https://doi.org/10.1016/j.ejphar.2003.11.063
https://doi.org/10.1016/j.ejphar.2003.11.063
Autor:
Laurent Findji, Philippe Lechat, Paul M. Vanhoutte, Odile Médiani, Nathalie Mougenot, Romain Bos
Publikováno v:
Journal of cardiovascular pharmacology. 45(1)
In heart failure, the renin-angiotensin-aldosterone and the sympathetic systems are overactivated and lead to formation of cardiac fibrosis, which contributes to the aggravation of cardiac function. The aim of the present study was to evaluate the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b175caf7fcdb70d6df7ba74c6222d
https://pubmed.ncbi.nlm.nih.gov/15613973
https://pubmed.ncbi.nlm.nih.gov/15613973
Publikováno v:
Pharmacological research. 51(4)
Anti-hypertensive agents may differently stimulate compensatory neuro-hormonal mechanisms and induce different effects on the cardiovascular remodeling and function. The combination of low doses of the two synergistic drugs may lead to a lesser activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2943044b98872d07388067b0d36d262c
https://pubmed.ncbi.nlm.nih.gov/15683750
https://pubmed.ncbi.nlm.nih.gov/15683750
Autor:
Laurent Findji, Gilles Le Naour, Nathalie Mougenot, Naïma Hanoun, Philippe Lechat, Michel Hamon, Fazia Brouri, Odile Médiani
Publikováno v:
European journal of pharmacology. 456(1-3)
The aim of our study was to analyse the mechanisms underlying cardiac toxicity caused by beta-adrenoceptor stimulation and the relationships with their associated downregulation during heart failure. We used the experimental model of coronary artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbe5625d97458a61b3e9ca83b23491c
https://pubmed.ncbi.nlm.nih.gov/12450571
https://pubmed.ncbi.nlm.nih.gov/12450571