Autoantibodies recognizing citrullinated rat filaggrin in an ELISA using citrullinated and non-citrullinated recombinant proteins as antigens are highly diagnostic for rheumatoid arthritis

Autor: Michel Jolivet, B Inçaurgarat, Dominique Rolland, Fabienne Jouen-Beades, X. Le Loët, Alain Daragon, A Gayet, Gaspard Gervasi, J Legoedec, P. Fardellone, Odile Letourneur, François Tron, Jean-François Ménard, Olivier Vittecoq

Publikováno v: Clinical and Experimental Immunology. 135:173-180

SUMMARY The objective of the study was to determine the diagnostic value for rheumatoid arthritis (RA) of anti-filaggrin autoantibodies (autoAb) recognizing citrullinated recombinant rat filaggrin (ACRF) in community cases of very early arthritis. To

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b4a476f6d87226e0f67e695be3cec7
https://doi.org/10.1111/j.1365-2249.2004.02341.x

Characterization and diagnostic potential of hepatitis B virus nucleocapsid expressed in E. coli and P. pastoris

Autor: Bénédicte, Watelet, Martine, Quibriac, Dominique, Rolland, Gaspard, Gervasi, Marie, Gauthier, Michel, Jolivet, Odile, Letourneur

Publikováno v: Journal of Virological Methods. 99:99-114

The hepatitis B core antigen (HBcAg) was expressed in Escherichia coli and in Pichia pastoris. A hexahistidine tag was introduced at the C terminus of the E. coli expressed protein allowing its purification by Ni(2+)-chelate affinity chromatography.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56597d84c2452512e3d21c0262fda549
https://doi.org/10.1016/s0166-0934(01)00385-8

Ligand-Induced Dimerization of the Extracellular Domain of the TGF-β Receptor Type II

Autor: Michel A. Horisberger, Jean-Francois Goetschy, Odile Letourneur, Markus G. Grütter

Publikováno v: Biochemical and Biophysical Research Communications. 224:709-716

Transforming growth factor-beta (TGF-beta) signals by mediating the association of two distinct transmembrane serine/threonine kinase receptors, the type I (T beta RI) and II (T beta RII). Here, we took advantage of recombinant human T beta RII extra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608a178c819fc1031a6c62ee8c9e4386
https://doi.org/10.1006/bbrc.1996.1088

Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor

Autor: Marie-Hélène Jouvin, M Adamczewski, A. Valle, Jean-Pierre Kinet, Odile Letourneur, Robert Numerof

Publikováno v: Journal of Biological Chemistry. 269:5918-5925

Nonreceptor tyrosine kinases such as the newly described 70-kDa (ZAP-70/Syk) and Src-related tyrosine kinases are coupled to a variety of receptors, including the antigen receptors on B- and T-cells and the Fc receptors for IgE (Fc epsilon RI) and Ig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::742d3c6c8646422f6e0d2d8e5cd52b09
https://doi.org/10.1016/s0021-9258(17)37549-x

Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response

Autor: Nicole Battail-Poirot, Geneviève Sibaï, Marie Gauthier, Marc Graille, Marie-Hélène Le Du, Odile Letourneur, Frédéric Ducancel, Dominique Rolland, Bruno H. Muller, Enrico A. Stura, Marc Bossus

Publikováno v: Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2005, 354, pp.447-458. ⟨10.1016/j.jmb.2005.09.028⟩
Journal of Molecular Biology, 2005, 354, pp.447-458. ⟨10.1016/j.jmb.2005.09.028⟩

Toxoplasma gondii, the intracellular parasite responsible for toxoplasmosis infects more than one-third of the world population and can be life-threatening for fetuses and immunocompromised patients. The surface protein SAG1 is an important immune ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f578976f643bb98b38a42200863776a
https://pubmed.ncbi.nlm.nih.gov/16242717