Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Odile Gayet"'
Autor:
Gabriela Reyes-Castellanos, Nadine Abdel Hadi, Scarlett Gallardo-Arriaga, Rawand Masoud, Julie Garcia, Sophie Lac, Abdessamad El Kaoutari, Tristan Gicquel, Mélanie Planque, Sarah-Maria Fendt, Laetitia Karine Linares, Odile Gayet, Fabienne Guillaumond, Nelson Dusetti, Juan Iovanna, Alice Carrier
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106899- (2023)
Summary: Pancreatic ductal adenocarcinoma (PDAC) remains one of the human cancers with the poorest prognosis. Interestingly, we found that mitochondrial respiration in primary human PDAC cells depends mainly on the fatty acid oxidation (FAO) to meet
Externí odkaz:
https://doaj.org/article/a215de16132949808608621f7b7c9ed6
Autor:
Nicolas Alejandro Fraunhoffer, Analía Meilerman Abuelafia, Brice Chanez, Martin Bigonnet, Odile Gayet, Julie Roques, Eduardo Chuluyan, Nelson Dusetti, Juan Iovanna
Publikováno v:
Cancer Communications, Vol 42, Iss 11, Pp 1212-1216 (2022)
Externí odkaz:
https://doaj.org/article/22b06ccf23c24506a8cd3b2ca74690ce
Autor:
Nicolas A. Fraunhoffer, Analía Meilerman Abuelafia, Martin Bigonnet, Odile Gayet, Julie Roques, Remy Nicolle, Gwen Lomberk, Raul Urrutia, Nelson Dusetti, Juan Iovanna
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-16 (2022)
Abstract Pancreatic ductal adenocarcinoma (PDAC), has recently been found to be a heterogeneous disease, although the extension of its diversity remains to be fully understood. Here, we harmonize transcriptomic profiles derived from both PDAC epithel
Externí odkaz:
https://doaj.org/article/a5b3a69ba8654764938ebaff607fad99
Autor:
Juan Liu, Chao Chen, Tuo Wei, Odile Gayet, Céline Loncle, Laurence Borge, Nelson Dusetti, Xiaowei Ma, Domenico Marson, Erik Laurini, Sabrina Pricl, Zhongwei Gu, Juan Iovanna, Ling Peng, Xing‐Jie Liang
Publikováno v:
Exploration, Vol 1, Iss 1, Pp 21-34 (2021)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer with no efficacious treatment. The application of nanomedicine is expected to bring new hope to PDAC treatment. In this study, we report a novel supramolecular dendrimeric nanosystem
Externí odkaz:
https://doaj.org/article/25d176e235ed4690b1b1a9d6ceb43f3d
Autor:
Abdessamad El Kaoutari, Nicolas A. Fraunhoffer, Owen Hoare, Carlos Teyssedou, Philippe Soubeyran, Odile Gayet, Julie Roques, Gwen Lomberk, Raul Urrutia, Nelson Dusetti, Juan Iovanna
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103332- (2021)
Background: Although significant advances have been made recently to characterize the biology of pancreatic ductal adenocarcinoma (PDAC), more efforts are needed to improve our understanding and to face challenges related to the aggressiveness, high
Externí odkaz:
https://doaj.org/article/18428c397ab14a18aa80e64b946ea8a9
Autor:
Consuelo Gajate, Odile Gayet, Nicolas A. Fraunhoffer, Juan Iovanna, Nelson Dusetti, Faustino Mollinedo
Publikováno v:
Cancers, Vol 13, Iss 23, p 6124 (2021)
Pancreatic cancer is one of the most lethal malignancies with a poor and gloomy prognosis and the highest mortality-to-incidence ratio. Pancreatic cancer remains an incurable malignancy, and current therapies are ineffective. We isolated cancer stem
Externí odkaz:
https://doaj.org/article/8a4e7cb1e6a647cca022afa67fc8f534
Autor:
Rémy Nicolle, Yuna Blum, Pauline Duconseil, Charles Vanbrugghe, Nicolas Brandone, Flora Poizat, Julie Roques, Martin Bigonnet, Odile Gayet, Marion Rubis, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Aurélien de Reyniès, Marc Giovannini, Philippe Grandval, Stephane Garcia, Cindy Canivet, Jérôme Cros, Barbara Bournet, Vincent Moutardier, Marine Gilabert, Juan Iovanna, Nelson Dusetti, Louis Buscail
Publikováno v:
EBioMedicine, Vol 57, Iss , Pp 102858- (2020)
Background: A significant gap in pancreatic ductal adenocarcinoma (PDAC) patient's care is the lack of molecular parameters characterizing tumours and allowing a personalized treatment. Methods: Patient-derived xenografts (PDX) were obtained from 76
Externí odkaz:
https://doaj.org/article/8918a4bc9a304a27b1233f14ef9164aa
Autor:
Gwen Lomberk, Yuna Blum, Rémy Nicolle, Asha Nair, Krutika Satish Gaonkar, Laetitia Marisa, Angela Mathison, Zhifu Sun, Huihuang Yan, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Tamas Ordog, Jeong-Heon Lee, Gavin Oliver, Eric Klee, Vincent Moutardier, Odile Gayet, Benjamin Bian, Pauline Duconseil, Marine Gilabert, Martin Bigonnet, Stephane Garcia, Olivier Turrini, Jean-Robert Delpero, Marc Giovannini, Philippe Grandval, Mohamed Gasmi, Veronique Secq, Aurélien De Reyniès, Nelson Dusetti, Juan Iovanna, Raul Urrutia
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pancreatic ductal adenocarcinoma (PDAC) is a complex disease and its underlying epigenomic heterogeneity is not fully understood. Here, the authors utilize patient-derived PDAC xenografts to define the epigenomic landscape of PDAC, highlighting chrom
Externí odkaz:
https://doaj.org/article/ae929c3ce359431a8440a2e7a864fc2f
Autor:
Rémy Nicolle, Yuna Blum, Laetitia Marisa, Celine Loncle, Odile Gayet, Vincent Moutardier, Olivier Turrini, Marc Giovannini, Benjamin Bian, Martin Bigonnet, Marion Rubis, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Pauline Duconseil, Mohamed Gasmi, Mehdi Ouaissi, Aurélie Maignan, Gwen Lomberk, Jean-Marie Boher, Jacques Ewald, Erwan Bories, Jonathan Garnier, Anthony Goncalves, Flora Poizat, Jean-Luc Raoul, Veronique Secq, Stephane Garcia, Philippe Grandval, Marine Barraud-Blanc, Emmanuelle Norguet, Marine Gilabert, Jean-Robert Delpero, Julie Roques, Ezequiel Calvo, Fabienne Guillaumond, Sophie Vasseur, Raul Urrutia, Aurélien de Reyniès, Nelson Dusetti, Juan Iovanna
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2458-2470 (2017)
Preclinical models based on patient-derived xenografts have remarkable specificity in distinguishing transformed human tumor cells from non-transformed murine stromal cells computationally. We obtained 29 pancreatic ductal adenocarcinoma (PDAC) xenog
Externí odkaz:
https://doaj.org/article/1cd281d48e1a47c3af7a5a5caffb63ca
Autor:
Owen Hoare, Nicolas Fraunhoffer, Abdessamad Elkaoutari, Odile Gayet, Martin Bigonnet, Julie Roques, Rémy Nicolle, Colin McGuckin, Nico Forraz, Emilie Sohier, Laurie Tonon, Pauline Wajda, Sandrine Boyault, Valéry Attignon, Séverine Tabone-Eglinger, Sandrine Barbier, Caroline Mignard, Olivier Duchamp, Juan Iovanna, Nelson J. Dusetti
Publikováno v:
Cancers, Vol 13, Iss 10, p 2473 (2021)
Purpose: Compare pancreatic ductal adenocarcinoma (PDAC), preclinical models, by their transcriptome and drug response landscapes to evaluate their complementarity. Experimental Design: Three paired PDAC preclinical models—patient-derived xenograft
Externí odkaz:
https://doaj.org/article/70e80687edfd4561a88c2c6ad681d19d