Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Odette Leiter"'
Autor:
Odette Leiter, David Brici, Stephen J. Fletcher, Xuan Ling Hilary Yong, Jocelyn Widagdo, Nicholas Matigian, Adam B. Schroer, Gregor Bieri, Daniel G. Blackmore, Perry F. Bartlett, Victor Anggono, Saul A. Villeda, Tara L. Walker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract The beneficial effects of physical activity on brain ageing are well recognised, with exerkines, factors that are secreted into the circulation in response to exercise, emerging as likely mediators of this response. However, the source and i
Externí odkaz:
https://doaj.org/article/d8e83ff214284a649830da1f3c2ec9ee
An exercise 'sweet spot' reverses cognitive deficits of aging by growth-hormone-induced neurogenesis
Autor:
Daniel G. Blackmore, Frederik J. Steyn, Alison Carlisle, Imogen O’Keeffe, King-Year Vien, Xiaoqing Zhou, Odette Leiter, Dhanisha Jhaveri, Jana Vukovic, Michael J. Waters, Perry F. Bartlett
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103275- (2021)
Summary: Hippocampal function is critical for spatial and contextual learning, and its decline with age contributes to cognitive impairment. Exercise can improve hippocampal function, however, the amount of exercise and mechanisms mediating improveme
Externí odkaz:
https://doaj.org/article/3047f38d7a0d44598f65f789ccf182a5
Autor:
Odette Leiter, Suse Seidemann, Rupert W. Overall, Beáta Ramasz, Nicole Rund, Sonja Schallenberg, Tatyana Grinenko, Ben Wielockx, Gerd Kempermann, Tara L. Walker
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 667-679 (2019)
Summary: Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved. Here we show that pl
Externí odkaz:
https://doaj.org/article/647ef407cd864a6f801032fdd6a4771a
Autor:
Alexandra Pötzsch, Sara Zocher, Stefanie N. Bernas, Odette Leiter, Annette E. Rünker, Gerd Kempermann
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102126- (2021)
Summary: L-lactate has energetic and signaling properties, and its availability is modulated by activity-dependent stimuli, which also regulate adult hippocampal neurogenesis. Studying the effects of L-lactate on neural precursor cells (NPCs) in vitr
Externí odkaz:
https://doaj.org/article/36cdd62893eb4081aa6a3c4cac2cb190
Autor:
Odette Leiter, Tara L. Walker
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
It is now apparent that platelet function is more diverse than originally thought, shifting the view of platelets from blood cells involved in hemostasis and wound healing to major contributors to numerous regulatory processes across different tissue
Externí odkaz:
https://doaj.org/article/c9147988c056410fb94b3a25349d2dc2
Publikováno v:
Bio-Protocol, Vol 7, Iss 21 (2017)
There are two neurogenic niches in the adult mammalian brain: the subventricular zone of the lateral ventricle and the subgranular zone of the hippocampal dentate gyrus. Cells from these areas can be isolated and maintained in vitro, using two differ
Externí odkaz:
https://doaj.org/article/6b79d6c2b50f4992b8a297951bb07d4e
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Immune regulation of the brain is generally studied in the context of injury or disease. Less is known about how the immune system regulates the brain during normal brain function. Recent work has redefined the field of neuroimmunology and, as long a
Externí odkaz:
https://doaj.org/article/0905724f8aee40339c7e917e34b8ce4c
Delayed and transient increase of adult hippocampal neurogenesis by physical exercise in DBA/2 mice.
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83797 (2013)
This study builds on the findings that physical activity, such as wheel running in mice, enhances cell proliferation and neurogenesis in the adult hippocampus of the common mouse strain C57BL/6, and that the baseline level of neurogenesis varies by s
Externí odkaz:
https://doaj.org/article/92254176b7af4606918c6b3c33dca5c6
Publikováno v:
Neurology, Psychiatry and Brain Research. 32:104-110
Background: Rodent and human studies indicate that testosterone has an antidepressant effect. The mechanisms via which testosterone exerts its antidepressant effect, however, remain to be elucidated. Some studies assume downstream effects of testoste
Autor:
Ben Wielockx, Gerd Kempermann, Tara L. Walker, Suse Seidemann, Sonja Schallenberg, Odette Leiter, Tatyana Grinenko, Beáta Ramasz, Nicole Rund, Rupert W. Overall
Publikováno v:
Stem Cell Reports, Vol 12, Iss 4, Pp 667-679 (2019)
Stem cell reports 12(4), 667-679 (2019). doi:10.1016/j.stemcr.2019.02.009
Stem Cell Reports
Stem cell reports 12(4), 667-679 (2019). doi:10.1016/j.stemcr.2019.02.009
Stem Cell Reports
Summary Physical activity is a strong positive physiological modulator of adult neurogenesis in the hippocampal dentate gyrus. Although the underlying regulatory mechanisms are still unknown, systemic processes must be involved. Here we show that pla