Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Odette Grech-Bélanger"'
Autor:
Jacques Turgeon, Andrew C. G. Uprichard, Dean W.G. Harron, Odette Grech-Bélanger, Pierre M. Bélanger
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:630-635
Resolution of mexiletine enantiomers from the racemic mixture has been achieved by fractional crystallization through the formation of diastereoisomeric p-toluoyl tartrate salts. Following three crystallization steps in methanol, R-(–)- and S-(+)-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63caf3dc855248b78c3b41c5d1586439
https://doi.org/10.1111/j.2042-7158.1991.tb03552.x
https://doi.org/10.1111/j.2042-7158.1991.tb03552.x
Autor:
Jacques Turgeon, P M Bélanger, Liliane Ayotte Ferron, Veronique Michaud, Marcel Gilbert, Line Labbé, Mohamad Samer Mouksassi, Odette Grech-Bélanger
Publikováno v:
Therapeutic drug monitoring. 28(6)
CYP1A2 is involved in the metabolism of both caffeine and propafenone, a class Ic antiarrhythmic agent. Despite the widespread consumption of caffeine, drug-drug interactions with this agent are often overlooked. This study investigated effects of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56ffeaac765a4a97326b8e8d97b7fdc1
https://pubmed.ncbi.nlm.nih.gov/17164694
https://pubmed.ncbi.nlm.nih.gov/17164694
Autor:
Jacques Turgeon, M Mouksassi, P M Bélanger, Marcel Gilbert, Veronique Michaud, Odette Grech-Bélanger, Line Labbé, M Lefebvre
Publikováno v:
Clinical Pharmacology & Therapeutics. 79:P21-P21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab27157a18d5d27c268fc6fc4693ca2
https://doi.org/10.1016/j.clpt.2005.12.074
https://doi.org/10.1016/j.clpt.2005.12.074
Publikováno v:
British Journal of Clinical Pharmacology. 21:481-487
The pharmacokinetics of S-(+)- and R-(-)-mexiletine and of the corresponding conjugates were investigated in six healthy young volunteers after administration of a single 200 mg oral dose of racemic mexiletine hydrochloride. The values for the distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f728255b398bc1ceb87253cc069ca482
https://doi.org/10.1111/j.1365-2125.1986.tb02829.x
https://doi.org/10.1111/j.1365-2125.1986.tb02829.x
Publikováno v:
Analytical Biochemistry. 118:47-52
A colorimetric method is described which can be used for the routine determination of primary and secondary N-hydroxylamino compounds in drug metabolism studies using microsomal preparations. The assay is carried out on the supernatant obtained after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabddf663d07086d48da955f6d074e29
https://doi.org/10.1016/0003-2697(81)90154-8
https://doi.org/10.1016/0003-2697(81)90154-8
Publikováno v:
Journal of chromatography. 337(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b8bd8bc831c6e273d9e2dcd37b3d1d
https://pubmed.ncbi.nlm.nih.gov/3980650
https://pubmed.ncbi.nlm.nih.gov/3980650
Publikováno v:
Journal of clinical pharmacology. 28(5)
The disposition of a single oral dose of diltiazem hydrochloride was studied in six male patients treated by continuous ambulatory peritoneal dialysis. Peak concentrations were obtained 2 to 4 hours postdose. The mean absorption rate constant was 0.9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33283f05e65ba8891fa73fc7fa017deb
https://pubmed.ncbi.nlm.nih.gov/3392246
https://pubmed.ncbi.nlm.nih.gov/3392246
Publikováno v:
Journal of chromatography. 228
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f65c4e6768b1d3affd922141d32701
https://pubmed.ncbi.nlm.nih.gov/7076756
https://pubmed.ncbi.nlm.nih.gov/7076756
Autor:
Elizabeth Leboeuf, Paul Kishka, Gilles Barbeau, M. Blouin, Odette Grech-Bélanger, Céline Fiset
Publikováno v:
Journal of clinical pharmacology. 29(4)
The effect of advancing age on the kinetics of the antiarrhythmic agent mexiletine was studied by comparing various kinetic parameters calculated after administration of a single oral dose of mexiletine hydrochloride to seven elderly and eight young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163008fd27dc5c77e3b1814bc1395917
https://pubmed.ncbi.nlm.nih.gov/2723119
https://pubmed.ncbi.nlm.nih.gov/2723119
Publikováno v:
Clinical pharmacology and therapeutics. 37(6)
The effect of cigarette smoking on the kinetics of a single, 200 mg, oral dose of the antiarrhythmic drug mexiletine was investigated in healthy subjects. Cigarette smoking had no effect on absorption or distribution of the drug, but it significantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add16f24ecaf8ef863d6763a8e9a0285
https://pubmed.ncbi.nlm.nih.gov/4006363
https://pubmed.ncbi.nlm.nih.gov/4006363