Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Odetta Antico"'
Autor:
Dipti Ranjan Lenka, Shakti Virendra Dahe, Odetta Antico, Pritiranjan Sahoo, Alan R Prescott, Miratul MK Muqit, Atul Kumar
Publikováno v:
eLife, Vol 13 (2024)
Loss-of-function Parkin mutations lead to early-onset of Parkinson’s disease. Parkin is an auto-inhibited ubiquitin E3 ligase activated by dual phosphorylation of its ubiquitin-like (Ubl) domain and ubiquitin by the PINK1 kinase. Herein, we demonst
Externí odkaz:
https://doaj.org/article/3f29e2a6e59d486a8abd2e720c70fea9
Publikováno v:
Data in Brief, Vol 49, Iss , Pp 109336- (2023)
The functional diversity of neurons is specified through their proteome resulting in elaborate and tightly regulated protein interaction networks and signalling that regulates neuronal processes. Dysregulation of these dynamic networks in development
Externí odkaz:
https://doaj.org/article/7b6b29df5b934ce8a239a22baf5b2808
Autor:
Thomas G. McWilliams, Erica Barini, Risto Pohjolan-Pirhonen, Simon P. Brooks, François Singh, Sophie Burel, Kristin Balk, Atul Kumar, Lambert Montava-Garriga, Alan R. Prescott, Sidi Mohamed Hassoun, François Mouton-Liger, Graeme Ball, Rachel Hills, Axel Knebel, Ayse Ulusoy, Donato A. Di Monte, Jevgenia Tamjar, Odetta Antico, Kyle Fears, Laura Smith, Riccardo Brambilla, Eino Palin, Miko Valori, Johanna Eerola-Rautio, Pentti Tienari, Olga Corti, Stephen B. Dunnett, Ian G. Ganley, Anu Suomalainen, Miratul M. K. Muqit
Publikováno v:
Open Biology, Vol 8, Iss 11 (2018)
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how this dyad orchestrates the elimination of damaged mitocho
Externí odkaz:
https://doaj.org/article/1d714fdf77f7434a8620cf73ff0a6aee
Autor:
Syed Arif Abdul Rehman, Elena Di Nisio, Chiara Cazzaniga, Odetta Antico, Axel Knebel, Clare Johnson, Frederic Lamoliatte, Rodolfo Negri, Miratul Muqit MK, Virginia De Cesare
E2 conjugating enzymes (E2s) play a central role in the enzymatic cascade that leads to the attachment of ubiquitin to a substrate. This process, termed ubiquitylation is fundamental for maintaining cellular homeostasis and impacts almost all cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5213529c293d7dae87454baf4c9f7290
https://doi.org/10.1101/2023.03.05.531151
https://doi.org/10.1101/2023.03.05.531151
Autor:
Michael U Stevens, Nathalie Croteau, Mohamed A Eldeeb, Odetta Antico, Zhi Wei Zeng, Rachel Toth, Thomas M Durcan, Wolfdieter Springer, Edward A Fon, Miratul MK Muqit, Jean-François Trempe
Publikováno v:
Life Science Alliance. 6:e202201419
Autosomal recessive mutations in the Parkin gene cause Parkinson’s disease. Parkin encodes an ubiquitin E3 ligase that functions together with the kinase PINK1 in a mitochondrial quality control pathway. Parkin exists in an inactive conformation me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bef42259c895b5077b144899ed2115
https://doi.org/10.26508/lsa.202201419
https://doi.org/10.26508/lsa.202201419
Autor:
J. Wade Harper, Alan R. Prescott, Michael Stevens, Rachel Toth, François Singh, Mollie L. Rickwood, Alban Ordureau, Erica Barini, Raja Sekhar Nirujogi, Marek Gierlinski, Odetta Antico, Miratul M. K. Muqit, Ian G. Ganley
Publikováno v:
Science Advances
Description
Identification of neuronal targets of PD-linked enzyme Parkin by quantitative ubiquitin-based proteomics.
How activation of PINK1 and Parkin leads to elimination of damaged mitochondria by mitophagy is largely based on cell line
Identification of neuronal targets of PD-linked enzyme Parkin by quantitative ubiquitin-based proteomics.
How activation of PINK1 and Parkin leads to elimination of damaged mitochondria by mitophagy is largely based on cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745faee6e57493e16aced5853e00b6d8
https://pubmed.ncbi.nlm.nih.gov/34767452
https://pubmed.ncbi.nlm.nih.gov/34767452
Autor:
Marek Gierlinski, François Singh, J. Wade Harper, Michael Stevens, Mollie L. Rickwood, Ian G. Ganley, Rachel Toth, Erica Barini, Alban Ordureau, Miratul M. K. Muqit, Odetta Antico, Alan R. Prescott
SUMMARYAutosomal recessive mutations in PINK1 and Parkin cause Parkinson’s disease. How activation of PINK1 and Parkin leads to elimination of damaged mitochondria by mitophagy is largely based on cell culture studies with few molecular studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c803753848da158735bf57b150a4319
https://doi.org/10.1101/2021.04.01.438131
https://doi.org/10.1101/2021.04.01.438131
Autor:
Mathieu Soetens, Satpal Virdee, Nicola T. Wood, Virginia De Cesare, Peter D. Mabbitt, Daniel Carbajo Lopez, Adam J. Fletcher, Odetta Antico
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The reversibility of ubiquitination by the action of deubiquitinating enzymes (DUBs) serves as an important regulatory layer within the ubiquitin system. Approximately 100 DUBs are encoded by the human genome, and many have been implicated with patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9214985f9b35dad7e01f1b8694bd9116
https://doi.org/10.1073/pnas.2006947118
https://doi.org/10.1073/pnas.2006947118
Autor:
Lennart Brandenburg, Gino Nardocci, Renata F. Soares, Francisco Bustos, Anna Segarra-Fas, Joby Varghese, Thomas Macartney, Jennifer Moran, Lindsay Davidson, Andrew Cassidy, Greg M. Findlay, C. James Hastie, Odetta Antico, Robert Gourlay, Rachel Toth, Martin Montecino
Publikováno v:
Developmental Cell
Summary Conserved protein kinases with core cellular functions have been frequently redeployed during metazoan evolution to regulate specialized developmental processes. The Ser/Arg (SR)-rich splicing factor (SRSF) protein kinase (SRPK), which is imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edaaa70d89339305c3046e2743f095e
https://doi.org/10.1016/j.devcel.2020.09.025
https://doi.org/10.1016/j.devcel.2020.09.025
Autor:
Alan R. Prescott, Graeme Ball, Kyle Fears, Miratul M. K. Muqit, Pentti J. Tienari, Axel Knebel, Johanna Eerola-Rautio, Riccardo Brambilla, Sophie Burel, Lambert Montava-Garriga, Simon Philip Brooks, Odetta Antico, Anu Suomalainen, Ayse Ulusoy, Rachel Hills, Olga Corti, François Mouton-Liger, Eino Palin, Ian G. Ganley, Donato A. Di Monte, Kristin Balk, Jevgenia Tamjar, Thomas G. McWilliams, Laura Smith, François Singh, Stephen B. Dunnett, Risto Pohjolan-Pirhonen, Atul Kumar, Sidi Mohamed Hassoun, Erica Barini, Miko Valori
Publikováno v:
Open Biology
'Open Biology ', vol: 8, pages: 180108-1-180108-18 (2018)
Open biology 8(11), 180108 (2018). doi:10.1098/rsob.180108
Open Biology, Vol 8, Iss 11 (2018)
'Open Biology ', vol: 8, pages: 180108-1-180108-18 (2018)
Open biology 8(11), 180108 (2018). doi:10.1098/rsob.180108
Open Biology, Vol 8, Iss 11 (2018)
Mutations in PINK1 and Parkin result in autosomal recessive Parkinson's disease (PD). Cell culture and in vitro studies have elaborated the PINK1-dependent regulation of Parkin and defined how this dyad orchestrates the elimination of damaged mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7baefaa2863884eb308aad3466aa3ab2
http://europepmc.org/articles/PMC6282074
http://europepmc.org/articles/PMC6282074