The PornLoS Treatment Program: Study protocol of a new psychotherapeutic approach for treating pornography use disorder.

Autor: Stark R; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany.; 2Center of Mind, Brain and Behavior, Universities of Marburg und Giessen, Giessen, Germany.; 3LOEWE Center DYNAMIC, University of Marburg, Marburg, Germany., Markert C; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Golder S; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Psarros R; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Discher JP; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Khatib S; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Metzger J; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Palmer S; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Rechmann J; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Storz F; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany., Walter B; 1Department for Psychotherapy and Systems Neuroscience, Justus-Liebig University of Giessen, Giessen, Germany.; 2Center of Mind, Brain and Behavior, Universities of Marburg und Giessen, Giessen, Germany., Allard S; 4Department of Clinical Psychology and Psychotherapy, Goethe University Frankfurt, Frankfurt, Germany., Antons S; 5General Psychology: Cognition, Faculty of Computer Science, University of Duisburg-Essen, Germany.; 6Center for Behavioral Addiction Research (CeBAR), Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Germany.; 7Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany., Bledzka M; 8AWKV, Cognitive Behavioral Training Center, Kassel, Germany., Brand M; 5General Psychology: Cognition, Faculty of Computer Science, University of Duisburg-Essen, Germany.; 6Center for Behavioral Addiction Research (CeBAR), Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Germany.; 7Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany., Dörrenbächer S; 9Clinical Psychology and Psychotherapy, Saarland University, Saarbruecken, Germany., Englisch J; 10Techniker Krankenkasse Hamburg, Hamburg, Germany., Friehs T; 11Department of Adult Clinical Psychology and Psychotherapy, University of Kaiserslautern-Landau (RPTU), Landau, Germany., Da Cunha Gonçalves K; 12Department of Clinical Psychology and Psychotherapy for Adults, School of Human Sciences, Osnabrück University, Osnabrück, Germany., Haberkamp A; 13Clinical Psychology and Psychotherapy, Marburg University, Marburg, Germany., Hall M; 14Department of Clinical Psychology and Psychotherapy, University of Trier, Trier, Germany., Kananian S; 4Department of Clinical Psychology and Psychotherapy, Goethe University Frankfurt, Frankfurt, Germany., Kemmerer P; 15Department of Psychosomatic Medicine and Psychotherapy, Outpatient Clinic for Behavioral Addictions, University Medical Center Mainz, Germany., Klingelhöfer D; 8AWKV, Cognitive Behavioral Training Center, Kassel, Germany., Lutz W; 14Department of Clinical Psychology and Psychotherapy, University of Trier, Trier, Germany., Melzig CA; 16Clinical Psychology, Experimental Psychopathology and Psychotherapy, Marburg University, Marburg, Germany., Michael T; 9Clinical Psychology and Psychotherapy, Saarland University, Saarbruecken, Germany., Neumann A; 17Institute for Health Care Management and Research, University Duisburg-Essen, Essen, Germany., Neusser S; 17Institute for Health Care Management and Research, University Duisburg-Essen, Essen, Germany., Niemann A; 17Institute for Health Care Management and Research, University Duisburg-Essen, Essen, Germany., Odenthal M; 16Clinical Psychology, Experimental Psychopathology and Psychotherapy, Marburg University, Marburg, Germany., Rubel J; 12Department of Clinical Psychology and Psychotherapy for Adults, School of Human Sciences, Osnabrück University, Osnabrück, Germany., Schlierenkamp S; 18Essener Forschungsinstitut für Medizinmanagement (EsFoMed) GmbH, Essen, Germany., Speckemeier C; 18Essener Forschungsinstitut für Medizinmanagement (EsFoMed) GmbH, Essen, Germany., Ünlü L; 4Department of Clinical Psychology and Psychotherapy, Goethe University Frankfurt, Frankfurt, Germany., Vogt R; 11Department of Adult Clinical Psychology and Psychotherapy, University of Kaiserslautern-Landau (RPTU), Landau, Germany., Wölfling K; 15Department of Psychosomatic Medicine and Psychotherapy, Outpatient Clinic for Behavioral Addictions, University Medical Center Mainz, Germany., Zachariassen W; 19DAK-Gesundheit, Health Services Research, Hamburg, Germany., Zur Hausen G; 20Coordinating Center for Clinical Trials, Philipps-University Marburg, Germany., Heinz C; 20Coordinating Center for Clinical Trials, Philipps-University Marburg, Germany.

Publikováno v: Journal of behavioral addictions [J Behav Addict] 2024 Sep 04; Vol. 13 (3), pp. 854-870. Date of Electronic Publication: 2024 Sep 04 (Print Publication: 2024).

Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis.

Autor: Meder L; Friedrich-Alexander-Universität Erlangen-Nürnberg, Faculty of Medicine, Department of Experimental Medicine 1, Erlangen, Germany.; Mildred Scheel School of Oncology and., Orschel CI; Mildred Scheel School of Oncology and.; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Otto CJ; Mildred Scheel School of Oncology and.; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Koker M; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Brägelmann J; Mildred Scheel School of Oncology and.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.; Department of Translational Genomics and., Ercanoglu MS; Institute of Virology, Laboratory of Experimental Immunology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Dähling S; Institute of Virology, Laboratory of Experimental Immunology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Compes A; Mildred Scheel School of Oncology and.; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Selenz C; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Nill M; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany., Dietlein F; Department of Medical Oncology, Dana-Faber Cancer Institute, Boston, Massachusetts, USA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Florin A; Institute for Pathology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Eich ML; Institute for Pathology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Borchmann S; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Else Kröner Forschungskolleg Clonal Evolution in Cancer, University Hospital Cologne, Cologne, Germany.; German Hodgkin Study Group, Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Odenthal M; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.; Institute for Pathology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Blazquez R; University Hospital Regensburg, Department of Internal Medicine III, Hematology and Medical Oncology, Regensburg, Germany., Hilberg F; Department of Pharmacology, Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria., Klein F; Institute of Virology, Laboratory of Experimental Immunology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Hallek M; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Büttner R; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.; Institute for Pathology, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany., Reinhardt HC; Department of Hematology and Stem Cell Transplantation, West German Cancer Center, University Hospital Essen, German Cancer Consortium (DKTK), Essen, Germany., Ullrich RT; Mildred Scheel School of Oncology and.; Department I of Internal Medicine, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Faculty of Medicine at the University Hospital Cologne, Cologne, Germany.

Publikováno v: JCI insight [JCI Insight] 2024 May 22; Vol. 9 (10). Date of Electronic Publication: 2024 May 22.

CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia.

Autor: Hirani DV; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany.; Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Institute for Lung Health (ILH) and Cardio-Pulmonary Institute (CPI), Gießen, Germany., Thielen F; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Mansouri S; Department of Lung Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Bad Nauheim, Germany., Danopoulos S; Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Vohlen C; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany.; Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Institute for Lung Health (ILH) and Cardio-Pulmonary Institute (CPI), Gießen, Germany.; Department of Pediatric and Adolescent Medicine, Faculty of Medicine, University Hospital Cologne, and University of Cologne, Cologne, Germany., Haznedar-Karakaya P; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Mohr J; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Wilke R; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Selle J; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Grosch T; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Mizik I; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany., Odenthal M; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Faculty of Medicine, and University of Cologne, Cologne, Germany.; Institute for Pathology, University Hospital Cologne, Faculty of Medicine, and University of Cologne, Cologne, Germany., Alvira CM; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA., Kuiper-Makris C; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany.; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Faculty of Medicine, and University of Cologne, Cologne, Germany., Pryhuber GS; Department of Pediatrics, Division of Neonatology, University of Rochester Medical Center, Rochester, NY, USA., Pallasch C; Department I of Internal Medicine, Center for Integrated Oncology (CIO) Köln-Bonn, University of Cologne, Cologne, Germany., van Koningsbruggen-Rietschel S; Department of Pediatric and Adolescent Medicine, Faculty of Medicine, University Hospital Cologne, and University of Cologne, Cologne, Germany., Al-Alam D; Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Seeger W; Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Institute for Lung Health (ILH) and Cardio-Pulmonary Institute (CPI), Gießen, Germany.; Department of Lung Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Bad Nauheim, Germany., Savai R; Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Institute for Lung Health (ILH) and Cardio-Pulmonary Institute (CPI), Gießen, Germany.; Department of Lung Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Bad Nauheim, Germany., Dötsch J; Department of Pediatric and Adolescent Medicine, Faculty of Medicine, University Hospital Cologne, and University of Cologne, Cologne, Germany., Alejandre Alcazar MA; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics, Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, Kerpener Strasse 62, Cologne, 50937, Germany. miguel.alejandre-alcazar@uk-koeln.de.; Universities of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL), Institute for Lung Health (ILH) and Cardio-Pulmonary Institute (CPI), Gießen, Germany. miguel.alejandre-alcazar@uk-koeln.de.; Center for Molecular Medicine Cologne (CMMC), University Hospital Cologne, Faculty of Medicine, and University of Cologne, Cologne, Germany. miguel.alejandre-alcazar@uk-koeln.de.; Cologne Excellence Cluster On Stress Responses in Aging-Associated Diseases (CECAD), University Hospital of Cologne, University of Cologne, Cologne, Germany. miguel.alejandre-alcazar@uk-koeln.de.

Publikováno v: Inflammation and regeneration [Inflamm Regen] 2023 Oct 24; Vol. 43 (1), pp. 52. Date of Electronic Publication: 2023 Oct 24.

E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response.

Autor: Anton V; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany., Buntenbroich I; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany., Simões T; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany., Joaquim M; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), Cologne, Germany., Müller L; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany., Buettner R; Center for Molecular Medicine Cologne (CMMC), Cologne, Germany; Institute of Pathology, Medical Faculty, University Hospital, University of Cologne, Germany., Odenthal M; Center for Molecular Medicine Cologne (CMMC), Cologne, Germany; Institute of Pathology, Medical Faculty, University Hospital, University of Cologne, Germany., Hoppe T; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), Cologne, Germany., Escobar-Henriques M; Institute for Genetics, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Cologne, Germany; Center for Molecular Medicine Cologne (CMMC), Cologne, Germany. Electronic address: mafalda.escobar@uni-koeln.de.

Publikováno v: Molecular cell [Mol Cell] 2023 Aug 17; Vol. 83 (16), pp. 2976-2990.e9.

Differential Role of Aldosterone and Transforming Growth Factor Beta-1 in Cardiac Remodeling.

Autor: Kmieć P; Department of Endocrinology and Internal Medicine, Medical University of Gdańsk, 80214 Gdańsk, Poland., Rosenkranz S; Clinic for Internal Medicine III and Cologne Cardiovascular Research Center, Cologne University Heart Center, 50937 Köln, Germany., Odenthal M; Institute of Pathology, University Hospital of Cologne and Center for Molecular Medicine, University of Cologne, 50937 Köln, Germany., Caglayan E; Department of Cardiology, University-Medicine Rostock, 18057 Rostock, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 31; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 31.