Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Oded Suad"'
Publikováno v:
Biochemical and Biophysical Research Communications. 418:408-413
MyoD is a tissue-specific transcriptional activator that acts as a master switch for muscle development. It activates a broad array of muscle-specific genes, which leads to conversion of proliferating myoblasts into mature myotubes. The ubiquitin pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1bdac43463ee223abeeae4fa732783e
https://doi.org/10.1016/j.bbrc.2012.01.045
https://doi.org/10.1016/j.bbrc.2012.01.045
Autor:
Zippora Shakked, Remo Rohs, Malka Kitayner, Dov Rabinovich, Barry Honig, Haim Rozenberg, Oded Suad
Publikováno v:
Nature Structural & Molecular Biology. 17:423-429
p53 binds as a tetramer to DNA targets consisting of two decameric half-sites separated by a variable spacer. Here we present high-resolution crystal structures of complexes between p53 core-domain tetramers and DNA targets consisting of contiguous h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84792dac89fbaaf7da4d5cd4cddefd98
https://doi.org/10.1038/nsmb.1800
https://doi.org/10.1038/nsmb.1800
Autor:
Naama Kessler, Oded Suad, Ditsa Levanon, Zippora Shakked, Immanuel Blumenzweig, Yoram Groner, Eran Eyal
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 24:343-357
The Runt domain proteins are eukaryotic transcription factors that regulate major developmental pathways. All members of this family contain a highly-conserved sequence-specific DNA binding domain: the Runt domain (RD). Structural and biochemical stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7197a366aecb9a1588c28a6acc9a3069
https://doi.org/10.1080/07391102.2007.10507124
https://doi.org/10.1080/07391102.2007.10507124
Autor:
Zippora Shakked, Ran Brosh, Linda J. W. Shimon, Oded Suad, Atar Liran, Yael Diskin-Posner, Varda Rotter, Felix Frolow, Naama Kessler, Haim Rozenberg
Publikováno v:
Journal of molecular biology. 385(1)
The tumor suppressor protein p53 is mutated in more than 50% of invasive cancers. About 30% of the mutations are found in six major "hot spot" codons located in its DNA binding core domain. To gain structural insight into the deleterious effects of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a63d5b343f77e9ffd2d2b64f7d7fd2
https://pubmed.ncbi.nlm.nih.gov/18996393
https://pubmed.ncbi.nlm.nih.gov/18996393