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Autor:
Daniel Zarhin, Refaela Atsmon, Antonella Ruggiero, Halit Baeloha, Shiri Shoob, Oded Scharf, Leore R. Heim, Nadav Buchbinder, Ortal Shinikamin, Ilana Shapira, Boaz Styr, Gabriella Braun, Michal Harel, Anton Sheinin, Nitzan Geva, Yaniv Sela, Takashi Saito, Takaomi Saido, Tamar Geiger, Yuval Nir, Yaniv Ziv, Inna Slutsky
Publikováno v:
Cell Reports
Summary Dysregulated homeostasis of neural activity has been hypothesized to drive Alzheimer’s disease (AD) pathogenesis. AD begins with a decades-long presymptomatic phase, but whether homeostatic mechanisms already begin failing during this silen