Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Oded Magger"'
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 9, p e1002690 (2012)
The prioritization of candidate disease-causing genes is a fundamental challenge in the post-genomic era. Current state of the art methods exploit a protein-protein interaction (PPI) network for this task. They are based on the observation that genes
Externí odkaz:
https://doaj.org/article/7834363c24674d03b2bf062a57563271
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 1, p e1000641 (2010)
A fundamental challenge in human health is the identification of disease-causing genes. Recently, several studies have tackled this challenge via a network-based approach, motivated by the observation that genes causing the same or similar diseases t
Externí odkaz:
https://doaj.org/article/1fb9af71822d4806a1326926929094e7
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 8, Iss 9, p e1002690 (2012)
PLoS Computational Biology, Vol 8, Iss 9, p e1002690 (2012)
The prioritization of candidate disease-causing genes is a fundamental challenge in the post-genomic era. Current state of the art methods exploit a protein-protein interaction (PPI) network for this task. They are based on the observation that genes
Publikováno v:
Bioinformatics. 27:3325-3326
Summary: PRINCIPLE is a Java application implemented as a Cytoscape plug-in, based on a previously published algorithm, PRINCE. Given a query disease, it prioritizes disease-related genes based on their closeness in a protein–protein interaction ne
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 1, p e1000641 (2010)
PLoS Computational Biology
PLoS Computational Biology
A fundamental challenge in human health is the identification of disease-causing genes. Recently, several studies have tackled this challenge via a network-based approach, motivated by the observation that genes causing the same or similar diseases t