Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Oded Danziger"'
Autor:
Phillip Cohen, Emma J. DeGrace, Oded Danziger, Roosheel S. Patel, Erika A. Barrall, Tesia Bobrowski, Thomas Kehrer, Anastija Cupic, Lisa Miorin, Adolfo García-Sastre, Brad R. Rosenberg
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT Single-cell RNA sequencing (scRNA-Seq) studies have provided critical insight into the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). scRNA-Seq librar
Externí odkaz:
https://doaj.org/article/088328c0e3864ff1a44427541b806e00
Autor:
Christina A. Higgins, Benjamin E. Nilsson-Payant, Boris Bonaventure, Andrew P. Kurland, Chengjin Ye, Tomer M. Yaron, Jared L. Johnson, Prithy Adhikary, Ilona Golynker, Maryline Panis, Oded Danziger, Brad R. Rosenberg, Lewis C. Cantley, Luis Martínez-Sobrido, Benjamin tenOever, Jeffrey R. Johnson
Publikováno v:
mBio, Vol 14, Iss 4 (2023)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, drastically modifies infected cells to optimize virus replication. One such modification is the activation
Externí odkaz:
https://doaj.org/article/f4d8484e81a64893a39af20ce68f7785
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010464 (2022)
Interferons establish an antiviral state through the induction of hundreds of interferon-stimulated genes (ISGs). The mechanisms and viral specificities for most ISGs remain incompletely understood. To enable high-throughput interrogation of ISG anti
Externí odkaz:
https://doaj.org/article/1e935b4c437d4d03ac0378f26c0767c1
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Malignancy-induced alterations to cytokine signaling in tumor cells differentially regulate their interactions with the immune system and oncolytic viruses. The abundance of inflammatory cytokines in the tumor microenvironment suggests that such sign
Externí odkaz:
https://doaj.org/article/e60ef7c58fdf4fd2abcb6d1ed4b6265b
Autor:
Phillip Cohen, Emma J DeGrace, Oded Danziger, Roosheel S Patel, Erika A Barrall, Tesia Bobrowski, Thomas Kehrer, Anastasija Cupic, Lisa Miorin, Adolfo García-Sastre, Brad R Rosenberg
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Single cell RNA sequencing (scRNAseq) studies have provided critical insight into the pathogenesis of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), the causative agent of COronaVIrus Disease 2019 (COVID-19). scRNAseq workflows are gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93590ebd41defd1640c47a49b32832b6
https://doi.org/10.1101/2021.11.22.469642
https://doi.org/10.1101/2021.11.22.469642
Autor:
Christina A. Higgins, Benjamin E. Nilsson-Payant, Andrew P. Kurland, Chengjin Ye, Tomer Yaron, Jared L. Johnson, Boris Bonaventure, Prithy Adhikary, Ilona Golynker, Maryline Panis, Oded Danziger, Brad R. Rosenberg, Lewis C. Cantley, Luis Martinez-Sobrido, Benjamin R. tenOever, Jeffrey R. Johnson
SARS-CoV-2, the causative agent of the COVID-19 pandemic, drastically modifies infected cells in an effort to optimize virus replication. Included is the activation of the host p38 mitogen-activated protein kinase (MAPK) pathway, which plays a major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf25b756c76ccfd4b75371b1616865cb
https://doi.org/10.1101/2021.08.20.457146
https://doi.org/10.1101/2021.08.20.457146
Autor:
Ignacio Mena, Beatriz M. A. Fontoura, Tadashi Makio, Thomas Kehrer, Elena Moreno, Maria Teresa Sánchez-Aparicio, Melissa B. Uccellini, Michael Schotsaert, Teresa Aydillo, Richard W. Wozniak, Sumit K. Chanda, Adolfo García-Sastre, Menghan Mei, Kris M. White, Ke Zhang, Oded Danziger, Brad R. Rosenberg, Xin Yin, Phillip Cohen, Roosheel S. Patel, Anastasija Cupic, Raveen Rathnasinghe, Laura Martin-Sancho, Lisa Miorin, Yi Ren, Nevan J. Krogan, Shengyan Gao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 45
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Significance To successfully establish infection, viral pathogens have to overcome the interferon (IFN)-mediated antiviral response. Previous studies revealed that the viral accessory protein Orf6 of SARS-CoV and SARS-CoV-2 is able to inhibit STAT1 n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555020bad50a2c2b24a24935300a51f0
https://escholarship.org/uc/item/00c2z9b4
https://escholarship.org/uc/item/00c2z9b4
Publikováno v:
Cellular and Molecular Life Sciences. 74:2645-2662
The Type-I bone morphogenetic protein receptors (BMPRs), BMPR1A and BMPR1B, present the highest sequence homology among BMPRs, suggestive of functional similitude. However, sequence elements within their extracellular domain, such as signal sequence
Autor:
Lu Lu, Mateusz Legut, Oded Danziger, Hemali Phatnani, Brad R. Rosenberg, Neville E. Sanjana, Silas Maniatis, Evan T. Geller, Tristan X. Jordan, Silva Kasela, Zharko Daniloski, Tuuli Lappalainen, Eleni P. Mimitou, Benjamin R. tenOever, Hans-Hermann Wessels, Peter Smibert, Daisy A. Hoagland
Publikováno v:
The Journal of Infection
Cell
Cell
To better understand host-virus genetic dependencies and find potential therapeutic targets for COVID-19, we performed a genome-scale CRISPR loss-of-function screen to identify host factors required for SARS-CoV-2 viral infection of human alveolar ep
Publikováno v:
Oncotarget
// Oded Danziger 1, * , Ben Shai 1, * , Yosef Sabo 1 , Eran Bacharach 1 , Marcelo Ehrlich 1 1 Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel * These authors contributed equal