Preclinical/clinical trials of thrice-weekly administration of a combination of tegafur/gimeracil/oteracil (TS-1) and toceranib phosphate in dogs with intranasal tumors.

Autor: Nishiyama Y; Veterinary Teaching Hospital, Azabu University, Kanagawa, Japan., Maruo T; Veterinary Teaching Hospital, Azabu University, Kanagawa, Japan.; School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Fukuyama Y; School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Odaka Y; School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Kawata E; School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Ueno H; School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Kayanuma H; School of Veterinary Medicine, Azabu University, Kanagawa, Japan., Nakayama T; Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Kanagawa, Japan., Takahashi H; Veterinary Teaching Hospital, Azabu University, Kanagawa, Japan.; School of Veterinary Medicine, Azabu University, Kanagawa, Japan.

Publikováno v: The Journal of veterinary medical science [J Vet Med Sci] 2024 Nov 01; Vol. 86 (11), pp. 1129-1135. Date of Electronic Publication: 2024 Oct 03.

MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ.

Autor: Schrenk S; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Bischoff LJ; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Goines J; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Cai Y; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Vemaraju S; Science of Light Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Odaka Y; The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Biology, University of Cincinnati Blue Ash College, Blue Ash, OH, USA., Good SR; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Palumbo JS; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.; Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Szabo S; Department of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA., Reynaud D; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Van Raamsdonk CD; Department of Medical Genetics, University of British Columbia, Vancouver, B.C., Canada., Lang RA; Science of Light Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; The Visual Systems Group, Abrahamson Pediatric Eye Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.; Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Boscolo E; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. elisa.boscolo@cchmc.org.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA. elisa.boscolo@cchmc.org.

Publikováno v: Nature communications [Nat Commun] 2023 Apr 06; Vol. 14 (1), pp. 1929. Date of Electronic Publication: 2023 Apr 06.

Clinical characteristics and long-term prognosis of contemporary patients with vasospastic angina: Ethnic differences detected in an international comparative study

Autor: Sato, K, Takahashi, J, Odaka, Y, Suda, A, Sueda, S, Teragawa, H, Ishii, K, Kiyooka, T, Hirayama, A, Sumiyoshi, T, Tanabe, Y, Kimura, K, Kaikita, K, Ong, P, Sechtem, U, Camici, PG, Kaski, JC, Crea, F, Beltrame, JF, Shimokawa, H, Japanese Coronary Spasm Association

BACKGROUND: Possible ethnic differences in clinical characteristics and long-term prognosis of contemporary patients with vasospastic angina (VSA) remain to be elucidated. METHODS AND RESULTS: The Japanese Coronary Spasm Association (JCSA) conducted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ddfefe57399a843e528f83c4514233f7

A Drosophila Su(H) model of Adams-Oliver Syndrome reveals cofactor titration as a mechanism underlying developmental defects.

Autor: Gagliani EK; Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America., Gutzwiller LM; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America., Kuang Y; Graduate program in Molecular and Developmental Biology, Cincinnati Children's Hospital Research Foundation, Cincinnati, Ohio, United States of America., Odaka Y; Biology Department, University of Cincinnati Blue Ash College, Cincinnati, Ohio, United States of America., Hoffmeister P; University Medical Center Ulm, Center for Internal Medicine, Department of Internal Medicine, Ulm, Germany., Hauff S; University Medical Center Ulm, Center for Internal Medicine, Department of Internal Medicine, Ulm, Germany., Turkiewicz A; Institute of Biochemistry, University of Giessen, Giessen, Germany., Harding-Theobald E; Department of Biology, Dartmouth College, Hanover, New Hampshire, United States of America., Dolph PJ; Department of Biology, Dartmouth College, Hanover, New Hampshire, United States of America., Borggrefe T; Institute of Biochemistry, University of Giessen, Giessen, Germany., Oswald F; University Medical Center Ulm, Center for Internal Medicine, Department of Internal Medicine, Ulm, Germany., Gebelein B; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America., Kovall RA; Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.

Publikováno v: PLoS genetics [PLoS Genet] 2022 Aug 11; Vol. 18 (8), pp. e1010335. Date of Electronic Publication: 2022 Aug 11 (Print Publication: 2022).

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