Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Odaine N. Gordon"'
Autor:
Fumie Nakashima, Takashi Suzuki, Odaine N. Gordon, Dominic Golding, Toshiaki Okuno, Juan A. Giménez-Bastida, Takehiko Yokomizo, Claus Schneider
Publikováno v:
JACS Au, Vol 1, Iss 9, Pp 1380-1388 (2021)
Externí odkaz:
https://doaj.org/article/767303db875b4c539101de30ffc05318
Autor:
Dominic Golding, Toshiaki Okuno, Juan Antonio Giménez-Bastida, Fumie Nakashima, Odaine N. Gordon, Takehiko Yokomizo, Claus Schneider, Takashi Suzuki
Publikováno v:
JACS Au, Vol 1, Iss 9, Pp 1380-1388 (2021)
Biosynthetic crossover of 5-lipoxygenase (5-LOX) and cyclooxygenase-2 (COX-2) enzymatic activities is a productive pathway to convert arachidonic acid into unique eicosanoids. Here we show that COX-2 catalysis with 5-LOX derived 5-hydroxy-eicosatetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5272916b1efaa32f447292c83065c2
https://doaj.org/article/767303db875b4c539101de30ffc05318
https://doaj.org/article/767303db875b4c539101de30ffc05318
Autor:
Odaine N. Gordon, Fumie Nakashima, Akil I. Joseph, Takahiro Shibata, Koji Uchida, Claus Schneider, Paula B. Luis
Publikováno v:
Biochemical Pharmacology. 132:143-149
Conjugation with glucuronic acid is a prevalent metabolic pathway of orally administrated curcumin, the bioactive diphenol of the spice turmeric. The major in vitro degradation reaction of curcumin is autoxidative transformation resulting in oxygenat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fec4232e5d05ab5e4fd4bedc480933f
https://doi.org/10.1016/j.bcp.2017.03.002
https://doi.org/10.1016/j.bcp.2017.03.002
Publikováno v:
Chemical Research in Toxicology. 28:989-996
Extracts from the rhizome of the turmeric plant are widely consumed as anti-inflammatory dietary supplements. Turmeric extract contains the three curcuminoids, curcumin (≈80% relative abundance), demethoxycurcumin (DMC; ≈15%), and bisdemethoxycur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c90c87a101cf38ee38e6578f94cb3c4
https://doi.org/10.1021/acs.chemrestox.5b00009
https://doi.org/10.1021/acs.chemrestox.5b00009
Publikováno v:
Journal of Agricultural and Food Chemistry. 63:7606-7614
Curcumin is the main bioactive ingredient in turmeric extract and widely consumed as part of the spice mix curry or as a dietary supplement. Turmeric has a long history of therapeutic application in traditional Asian medicine. Biomedical studies cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37c0a550c2b71819fafa5daa4c6f491a
https://doi.org/10.1021/acs.jafc.5b00244
https://doi.org/10.1021/acs.jafc.5b00244
Publikováno v:
Journal of Biological Chemistry. 290:4817-4828
Curcumin is a dietary anti-inflammatory and chemopreventive agent consisting of two methoxyphenol rings connected by a conjugated heptadienedione chain. Curcumin is unstable at physiological pH and rapidly degrades in an autoxidation reaction to a ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24ca33e2b1cc876ccc070cb85a5e1de5
https://doi.org/10.1074/jbc.m114.618785
https://doi.org/10.1074/jbc.m114.618785
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 56:696-699
Curcumin is a dietary diphenol with antioxidant, antinflammatory, and antitumor activity. We describe facile procedures for the synthesis of [14C2]curcumin (4 mCi/mmol), [d6]curcumin, [d3]curcumin, [13C5]curcumin, and [d6]bicyclopentadione, the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f139c67fd993dc68a0987f57ec14fc
https://doi.org/10.1002/jlcr.3102
https://doi.org/10.1002/jlcr.3102
Publikováno v:
Biochemistry. 52:221-227
The polyphenol curcumin is the principal flavor and color component of the spice turmeric. Beyond its culinary uses, curcumin is believed to positively impact human health and displays antioxidant, anti-inflammatory, antibacterial, and chemopreventiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e18640e44fb0fdff54a5d3019a6bc25
https://doi.org/10.1021/bi3014455
https://doi.org/10.1021/bi3014455
Autor:
Odaine N. Gordon, Claus Schneider
In a recent Opinion article Shen and Ji discussed the hypothesis that metabolites of curcumin, specifically vanillin and ferulic acid, could account for its striking poly-pharmacology as well as for the enigmatic low levels of curcumin in animal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a01b7ef25bb6daa4ab60ae7a67c342
https://europepmc.org/articles/PMC3739485/
https://europepmc.org/articles/PMC3739485/
Autor:
Odaine N. Gordon, Daniel P. Barry, Katherine A. Denney, Christopher S. Williams, Mohammad Asim, Rupesh Chaturvedi, Xinrui Qian, Keith T. Wilson, Noemi Tejera-Hernandez, Claus Schneider
Publikováno v:
Gastroenterology. 142:S-488
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9826416975ef244042bdf88ce7914b64
https://doi.org/10.1016/s0016-5085(12)61862-9
https://doi.org/10.1016/s0016-5085(12)61862-9